Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lorenzo Trippa"'
Autor:
Michael Constantine, Romualdo Barroso-Sousa, Tianyu Li, Eric P. Winer, Meredith Faggen, Antonio Di Meglio, Nabihah Tayob, Harold J. Burstein, Caroline Block, Natalie Faye Sinclair, Rebecca Rees, Nan Lin, Ann H. Partridge, Ines Vaz-Luis, Sara M. Tolaney, Jiani Hu, Michael J. Hassett, Jose Pablo Leone, Lindsey Milisits, Frederick Briccetti, Lorenzo Trippa, Adrienne G. Waks
Publikováno v:
The Oncologist
Background In early trials, hypersensitivity reactions (HSRs) to paclitaxel were common, thus prompting the administration of antihistamines and corticosteroids before every paclitaxel dose. We tested the safety of omitting corticosteroids after cycl
Autor:
Yoshinobu Konishi, Romanos Sklavenitis-Pistofidis, Hong Yue, Federico Ferrari, Robert A. Redd, Elizabeth D. Lightbody, Massimiliano Russo, Jacqueline Perry, Erica Horowitz, Anna V. Justis, Nader A. Shayegh, Alexandra Savell, Julia Prescott, Shohreh Varmeh, Radosław P. Nowak, Mark Hamilton, Daniel Auclair, Catherine R. Marinac, Lorenzo Trippa, Eric S. Fischer, Irene M. Ghobrial
Publikováno v:
Cancer Cell
Autor:
Habib El-Khoury, David J Lee, Jean-Baptiste Alberge, Robert Redd, Christian J Cea-Curry, Jacqueline Perry, Hadley Barr, Ciara Murphy, Dhananjay Sakrikar, David Barnidge, Mark Bustoros, Houry Leblebjian, Anna Cowan, Maya I Davis, Julia Amstutz, Cody J Boehner, Elizabeth D Lightbody, Romanos Sklavenitis-Pistofidis, Mark C Perkins, Stephen Harding, Clifton C Mo, Prashant Kapoor, Joseph Mikhael, Ivan M Borrello, Rafael Fonseca, Scott T Weiss, Elizabeth Karlson, Lorenzo Trippa, Timothy R Rebbeck, Gad Getz, Catherine R Marinac, Irene M Ghobrial
Publikováno v:
Lancet Haematol
Prevalence estimates for monoclonal gammopathy of undetermined significance (MGUS) are based on predominantly White study populations screened by serum protein electrophoresis supplemented with immunofixation electrophoresis. A prevalence of 3% is re
Autor:
Jose Pablo Leone, Michael J. Hassett, Caroline Block, Sara M. Tolaney, Jiani Hu, Meredith Faggen, Lindsey Milisits, Ines Vaz-Luis, Adrienne G. Waks, Natalie Faye Sinclair, Michael Constantine, Frederick Briccetti, Kelly O'Neil, Lorenzo Trippa, Rebecca Rees, Nan Lin, Antonio Di Meglio, Harold J. Burstein, Eric P. Winer, Romualdo Barroso-Sousa, Ann H. Partridge
Publikováno v:
Journal of Clinical Oncology
PURPOSE The use of growth factors adds considerable expense and some toxicity to adjuvant breast cancer chemotherapy. We tested the feasibility and safety of omitting routine peg-filgrastim use during the paclitaxel portion of the dose-dense doxorubi
Autor:
Justin Cha, Cody J. Boehner, Nikhil C. Munshi, Romanos Sklavenitis-Pistofidis, Kwee Yong, Chip Stewart, Karma Salem, Eliezer M. Van Allen, Jihye Park, Yu-Tzu Tai, Andrew Dunford, Shankara Anand, Lorenzo Trippa, Amaro Taylor-Weiner, Jacob P. Laubach, Mark Bustoros, Benny Zhitomirsky, Robert A. Redd, Selina J Chavda, Irene M. Ghobrial, Shaji Kumar, Paul G. Richardson, Kenneth C. Anderson, François Aguet, Tarek H. Mouhieddine, P. Leif Bergsagel, Gad Getz, Mahshid Rahmat, Tineke Casneuf, Meletios A. Dimopoulos, Liudmila Elagina, Carl Jannes Neuse, Salomon Manier, Elizabeth A. Morgan, Ignaty Leshchiner, Efstathis Kastritis
Publikováno v:
J Clin Oncol
PURPOSE Smoldering multiple myeloma (SMM) is a precursor condition of multiple myeloma (MM) with a 10% annual risk of progression. Various prognostic models exist for risk stratification; however, those are based on solely clinical metrics. The disco
Autor:
Robert A. Redd, Matthew Leventhal, Irene M. Ghobrial, Nikhil C. Munshi, Christopher J. Gibson, Jerome Ritz, Amin Nassar, Chip Stewart, Jihye Park, Romanos Sklavenitis-Pistofidis, Marzia Capelletti, Cody J. Boehner, David P. Steensma, Saud H. AlDubayan, Daniel Auclair, Lorenzo Trippa, Muhieddine M. Itani, Benjamin L. Ebert, Kalvis Hornburg, Shaadi Mehr, Mark Bustoros, Robert L. Schlossman, Henry Dumke, Jacob P. Laubach, Adam S. Sperling, Gad Getz, Salomon Manier, Paul G. Richardson, Eliezer M. Van Allen, Tarek H. Mouhieddine, Sabrin Tahri, Kenneth C. Anderson, Robert J. Soiffer, Daisy Huynh, Donna Neuberg, Brendan Reardon, Chia Jen Liu, Jonathan J Keats
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Nature Communications, 2020, 11 (1), pp.2996. ⟨10.1038/s41467-020-16805-5⟩
Multiple myeloma (MM) is a plasma-cell neoplasm that is treated with high-dose chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. The presence of somatic mutations in the peripheral blood is t
Autor:
Sara M. Tolaney, Eric P. Winer, Rebecca Rees, William T. Barry, Shom Goel, Lorenzo Trippa, Laura Spring, Sonia Pernas, Rie K. Tahara, Erica L. Mayer, Chelsea Andrews, Zhenying Tan-Wasielewski, Aditya Bardia
Publikováno v:
Clinical Breast Cancer. 19:399-404
Background Signaling through the cyclin-dependent kinase 4 and 6 (CDK4/6) pathway can mediate therapeutic resistance in HER2-positive breast cancer. Preclinical studies have demonstrated that CDK4/6 inhibitors can resensitize resistant HER2-positive
Autor:
Edie Weller, Kaitlen Reyes, James J. Vredenburgh, Adam Boruchov, Kimberly Noonan, Paul G. Richardson, Rachid Baz, Jacob P. Laubach, Abdel Kareem Azab, Houry Leblebjian, Robert L. Schlossman, Irene M. Ghobrial, Frank G. Basile, Pamela A. Crilley, Kenneth C. Anderson, Patrick Henrick, Michael Constantine, Stacey Chuma, Nikhil C. Munshi, Kenneth H. Shain, Kalvis Hornburg, Claudia E. Paba-Prada, Philippe Armand, Diane Warren, Yuji Mishima, Lorenzo Trippa, Chia Jen Liu, Oksana Zavidij
Publikováno v:
American Journal of Hematology. 94:1244-1253
We tested the hypothesis that using CXCR4 inhibition to target the interaction between the tumor cells and the microenvironment leads to sensitization of the tumor cells to apoptosis. Eligibility criteria included multiple myeloma (MM) patients with
Autor:
Shyam K. Tanguturi, Steffen Ventz, Jennifer R. Bellon, Shervin Tabrizi, Anthony V. D'Amico, Rifaquat Rahman, Daphne A. Haas-Kogan, Ayal A. Aizer, Brian M. Alexander, Geoffrey Fell, Lorenzo Trippa, Harvey J. Mamon, Daniel N. Cagney, Paul L. Nguyen
Publikováno v:
JAMA Network Open
Key Points Question How is the COVID-19 pandemic associated with risks and benefits of standard cancer therapy? Findings In this comparative effectiveness study reanalyzing data from 8 randomized trials across oncology, radiation fractionation was no
Autor:
Mark Bustoros, Daisy Huynh, Jorge J. Castillo, Steven P. Treon, Irene M. Ghobrial, Patrick Henrick, Bradley Rivotto, Adriana Perilla-Glen, Mairead Reidy, Chia Jen Liu, Oksana Zavidij, Romanos Sklavenitis-Pistofidis, Lorenzo Trippa, Alexandra Savell, Marzia Capelletti, Kaitlen Reyes
Publikováno v:
Blood. 132:2608-2612
TO THE EDITOR: Waldenstrom macroglobulinemia (WM) is a rare lymphoplasmacytic lymphoma associated with immunoglobulin M monoclonal gammopathy.[1][1] The majority of patients carry the L265P mutation in MYD88,[2][2] whereas 40% of patients carry mutat