Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kathy Medvik"'
Autor:
Michael M. Lederman, M. R. Sandhya Rani, Benigno Rodriguez, Kathy Medvik, Sara J. Conry, Johan K. Sandberg, Alan L. Landay, Ronald E. Blanton, Yngve Falck-Ytter, Donald D. Anthony
Publikováno v:
The Journal of Infectious Diseases. 206:969-973
Disease progression of human immunodeficiency virus type 1 (HIV-1) is associated with immune activation. Activation indices are higher during coinfection of hepatitis C virus (HCV) and HIV. The effect of immune activation on interferon α (IFN-α) th
Autor:
Grace A, McComsey, Ulrich A, Walker, Chakra B, Budhathoki, Zhaohui, Su, Judith S, Currier, Lisa, Kosmiski, Linda G, Naini, Stéphannie, Charles, Kathy, Medvik, Judith A, Aberg, Jolene, Noel-Connor
Publikováno v:
AIDS. 24:2507-2515
Lipoatrophy is prevalent on thymidine nucleoside reverse transcriptase inhibitors (tNRTIs). A pilot trial showed that uridine (NucleomaxX) increased limb fat.A5229 was a multicenter trial in which HIV-infected individuals with lipoatrophy on tNRTI re
Publikováno v:
Clinical Immunology. 136:400-408
Immune reconstitution after HAART is incomplete, but no widely accepted method to quantify subclinical immune deficiency is available. We immunized 9 HIV-negative subjects and 29 HIV-infected patients with CD4>/=450 cells/microL and undetectable HIV
Autor:
John Spritzler, Angela Malaspina, Savita Pahwa, Evgenia Aga, Kathy Medvik, Catherine A. Battaglia, Alan L. Landay, Irini Sereti, Margaret A. Fischl, Richard M. Dunham, Michael A. Proschan, David M. Asmuth, Lawrence Fox, Michel Morre, Michael M. Lederman, John D. Altman, Allan R. Tenorio, Guido Silvestri, Susan Moir, Renaud Buffet
Publikováno v:
Blood. 113:6304-6314
Interleukin 7 (IL-7) is a common gamma chain receptor cytokine implicated in thymopoiesis and in peripheral expansion and survival of T lymphocytes. The safety and activity of recombinant human IL-7 (rhIL-7) administration were therefore examined in
Autor:
Kim Y. Smith, Pablo Tebas, Benigno Rodriguez, David M. Margolis, Hildegund C.J. Ertl, Anne Sevin, Kathy Medvik, Hernan Valdez, Hongying Wang, Laura M. Smeaton, Scott F. Sieg, Richard B. Pollard, Michael M. Lederman, Minya Pu
Publikováno v:
The Journal of Infectious Diseases. 194:1677-1685
Background. Although the determinants of immune deficiency and immune restoration in chronic human immunodeficiency virus (HIV)-1 infection are not well understood, immune activation has been proposed as being central to the pathogenesis of HIV. Meth
Autor:
Michael M. Lederman, Kathy Medvik, Christoph Lange, Mary Wild, Robert Asaad, Robert C. Kalayjian, Hernan Valdez
Publikováno v:
AIDS. 17:2015-2023
OBJECTIVE To ascertain whether delaying the initiation of highly active antiretroviral therapy (HAART) compromises functional immune reconstitution in HIV-1 infection in persons who regain 'normal' CD4 T-cell counts after suppressive antiretroviral t
Publikováno v:
Clinical Immunology. 102:154-161
To evaluate the effects of the timing of highly active antiretroviral therapy (HAART) on immune reconstitution, we compared lymphocyte subpopulations and lymphocyte proliferation (LP) in response to Candida albicans, cytomegalovirus, HIV p24, Mycobac
Autor:
Robert C. Kalayjian, Robert Asaad, Grace A. McComsey, Alan J. Taege, Robert A. Salata, Hector Bonilla, Elizabeth Kirchner, Benigno Rodriguez, Nicholas T. Funderburg, Carey L. Shive, Brian Clagett, Michael M. Lederman, Barbara Gripshover, Leonard H. Calabrese, Michelle V. Lisgaris, Jane E. Baum, Scott F. Sieg, Kathy Medvik
Background. Failure to normalize CD4+ T-cell numbers despite effective antiretroviral therapy is an important problem in human immunodeficiency virus (HIV) infection. Methods. To evaluate potential determinants of immune failure in this setting, we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317dedcd304381182bdd64941a0bbbc0
https://europepmc.org/articles/PMC3218674/
https://europepmc.org/articles/PMC3218674/
Autor:
Michael M. Lederman, Judith A. Aberg, Kathy Medvik, Marion G. Peters, Margaret James Koziel, Edgar T. Overton, Minhee Kang, Triin Umbleja, Donald D. Anthony
Publikováno v:
Vaccine. 29(19)
We evaluated immunologic predictors of response to HBV vaccine administered in the presence or absence of GM-CSF in HIV infected individuals. We measured peripheral blood hematopoietic progenitor, monocyte and myeloid-derived suppressor cell (MDSC) f
Autor:
Rajesh T Gandhi, Lu Zheng, Ronald J Bosch, Ellen S Chan, David M Margolis, Sarah Read, Beatrice Kallungal, Sarah Palmer, Kathy Medvik, Michael M Lederman, Nadia Alatrakchi, Jeffrey M Jacobson, Ann Wiegand, Mary Kearney, John M Coffin, John W Mellors, Joseph J Eron, AIDS Clinical Trials Group A5244 team
Publikováno v:
PLoS Medicine, Vol 7, Iss 8 (2010)
PLoS Medicine
PLoS Medicine
In a double-blind trial, Rajesh Gandhi and colleagues detect no significant reduction in viral load after people with low-level HIV viremia added an integrase inhibitor to their treatment regimen.
Background Most HIV-1-infected patients on effec
Background Most HIV-1-infected patients on effec