Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karel Souček"'
Autor:
Stanislav Drápela, Miroslav Boudny, Josef Jaroš, Michaela Špunarová, Jan Verner, Prashant Khirsariya, Zuzana Jašková, Kamil Paruch, Yvona Brychtová, Marie Kasparkova, Jana Zemanová, Jiri Mayer, Marek Borsky, Václav Šeda, Jana Černá, Martin Trbušek, Alexandra Oltová, Marek Mráz, Karel Souček
Publikováno v:
Haematologica
Introduction of small-molecule inhibitors of B-cell receptor signaling and BCL2 protein significantly improves therapeutic options in chronic lymphocytic leukemia. However, some patients suffer from adverse effects mandating treatment discontinuation
Autor:
Vladimír Velebný, Matěj Šimek, Tereza Foglová, Lucia Binó, Karel Souček, Daniela Šmejkalová, Martina Hermannová
Publikováno v:
Carbohydrate Polymers. 209:181-189
A better understanding of in vivo behavior of nanocarriers is necessary for further improvement in their development. Here we present a novel approach, where both the matrix and the drug can be analyzed by LC MS/MS after one sample handling. The deve
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplasti
Autor:
Petr Dzubak, Zuzana Kahounová, Jiri Navratil, Dana Simkova, Gabriela Korinkova, Adéla Galandáková, Tereza Suchankova-Kleplova, Karel Souček, Tomáš Soukup, Jan Bouchal, Tomas Ozdian, Gvantsa Kharaishvili, Maria Janikova, Michal Krupka
Publikováno v:
Oncotarget
Asporin has been reported as a tumor suppressor in breast cancer, while asporin-activated invasion has been described in gastric cancer. According to our in silico search, high asporin expresion associates with significantly better relapse free survi
Autor:
Stanislav Lerch, Ján Remšík, Alois Kozubík, Monika Smějová, Jan Bouchal, Eva Slabáková, Gvantsa Kharaishvili, Zoran Culig, Milan Král, Zuzana Pernicová, Nicol Straková, Tereza Suchankova, Karel Souček
Publikováno v:
Oncotarget
// Eva Slabakova 1, 2 , Gvantsa Kharaishvili 3 , Monika Smějova 1, 4 , Zuzana Pernicova 1, 2 , Tereza Suchankova 1 , Jan Remsik 1, 2, 5 , Stanislav Lerch 1, 5 , Nicol Strakova 1, 2 , Jan Bouchal 3 , Milan Kral 6 , Zoran Culig 2, 7 , Alois Kozubik 1,
Autor:
Ladislav Dušek, Jiří Kohoutek, Jiřina Procházková, Michal Hofer, Ján Remšík, Marie Nováková, Radek Fedr, Aleš Hampl, Zuzana Hoferová, Karel Souček
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Several members of the TGF-ß family are known to effectively regulate the fate of hematopoietic progenitor cells in a complex and context-dependent manner. Growth differentiation factor-15 (GDF15) is a divergent member of the TGF-ß family. This str
Autor:
Sára Lenárt, Šárka Šimečková, Radek Fedr, Zuzana Kahounová, Jan Bouchal, Petr Beneš, Gvantsa Kharaishvili, Lucia Binó, Eva Slabáková, Milan Král, Tereza Kučírková, Ján Remšík, Lucia Knopfová, Karel Souček, Ximena Maria Muresan
Publikováno v:
Carcinogenesis. 39(11)
The cell surface glycoprotein Trop-2 is commonly overexpressed in carcinomas and represents an exceptional antigen for targeted therapy. Here, we provide evidence that surface Trop-2 expression is functionally connected with an epithelial phenotype i
Autor:
Tereza Suchankova, Karel Souček, Tomáš Soukup, Zuzana Kahounová, Alice Malenovská, Eva Slabáková, Ján Remšík, Jan Bouchal, Daniela Kurfürstová, Aleš Hampl, Zuzana Holubcová
Publikováno v:
Journal of assisted reproduction and genetics. 35(8)
PURPOSE: The purpose of the study was to determine whether the GDF-15 is present in follicular fluid; to evaluate if there is a relation between follicular and serum levels of GDF-15 and fertility status of study subjects; and to test whether granulo
Autor:
Radek Fedr, Jiří Navrátil, Pavel Fabian, Marek Svoboda, Eva Slabáková, Ján Remšík, Lucia Binó, Karel Souček
Publikováno v:
British Journal of Cancer
Background: The intratumoural heterogeneity, often driven by epithelial-to-mesenchymal transition (EMT), significantly contributes to chemoresistance and disease progression in adenocarcinomas. Methods: We introduced a high-throughput screening platf
Autor:
Zuzana, Kahounová, Daniela, Kurfürstová, Jan, Bouchal, Gvantsa, Kharaishvili, Jiří, Navrátil, Ján, Remšík, Šárka, Šimečková, Vladimír, Študent, Alois, Kozubík, Karel, Souček
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 93(9)
The identification of fibroblasts and cancer-associated fibroblasts from human cancer tissue using surface markers is difficult, especially because the markers used currently are usually not expressed solely by fibroblasts, and the identification of