Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Josee Gauthier"'
Autor:
Anna H. Owings, George E. Abraham, Haley B. Williams, Christian Jobin, Rachel C. Newsome, Sarah C. Glover, Raad Z. Gharaibeh, Maria C. Hernandez, Adam M. Parker, Meredith Sloan, Mohammad H. Hasan, Tanya O. Robinson, Michal Senitko, Josee Gauthier, Kenneth J. Wilson, Taylor Christian, Hannah Laird, Yilianys Pride
Publikováno v:
Gut Microbes
article-version (VoR) Version of Record
Gut Microbes, Vol 13, Iss 1 (2021)
article-version (VoR) Version of Record
Gut Microbes, Vol 13, Iss 1 (2021)
To investigate the relationship between intestinal microbiota and SARS-CoV-2-mediated pathogenicity in a United States, majority African American cohort. We prospectively collected fecal samples from 50 SARS-CoV-2 infected patients, 9 SARS-CoV-2 reco
Autor:
Tanya O. Robinson, Meredith Sloan, Raad Z. Gharaibeh, George E Abraham, Krishna K. Ayyalasomayajula, Bruce H. Horwitz, Christian Jobin, Brian Claggett, Sarah C. Glover, Julia J. Liu, Gill Diamond, Haley B. Williams, Fremel J. Backus, Michal Senitko, Josee Gauthier, Robert M. Adelman, Erika L. Figgins, Campbell B Sindel, Anna H. Owings, Adam M. Parker
Publikováno v:
The American journal of gastroenterology. 116(8)
INTRODUCTION: Proton pump inhibitor (PPI) use was recently reported to be associated with increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and worse clinical outcomes The underlying mechanism(s) for this association ar
Autor:
Mary K. Reinhard, Maria V. Guijarro, Steven J. Hughes, Anthony A. Fodor, Jillian L. Pope, Maria Zajac-Kaye, Christian Jobin, Raad Z. Gharaibeh, Rachel C. Newsome, Qin Yu, Kathryn Winglee, Jose G. Trevino, Ryan M. Thomas, Josee Gauthier, Mark Beveridge, Zhen He, Christina L. Ohland
Publikováno v:
Carcinogenesis
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death in the United States yet data are scant regarding host factors influencing pancreatic carcinogenesis. Increasing evidence support the role of the host microbiota in ca
Autor:
Michael Sioda, Sarah Bajorek, Anthony A. Fodor, Leslie A. Parker, James Johnson, Kathryn Winglee, Nan Li, Michael T. Weaver, Josee Gauthier, Dominick J. Lemas, Christian Jobin, Josef Neu, Graciela L. Lorca
Publikováno v:
Gut microbes. 10(3)
The purpose of this prospective cross-sectional cohort pilot study is to explore the initial microbial community of gastric aspirate fluid as collected immediately after birth and its relationships with mode of delivery and preterm birth. Twenty-nine
Autor:
Richard Ohrbach, Célia Marisa Rizzatti-Barbosa, Shad B. Smith, Samantha K. Segall, William Maixner, Roger B. Fillingim, Charles Knott, Pekka T. Männistö, Marc Parisien, Douglas Tsao, Josee Gauthier, Joel D. Greenspan, Marjo Piltonen, Carolina B. Meloto, Marino Convertino, Dmitri V. Zaykin, Luda Diatchenko, Ilkka Reenilä, Svetlana A. Shabalina, Nikolay V. Dokholyan, Gary D. Slade
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. A catechol-O-methyltransferase genetic marker of pain led to the discovery of an alternative enzyme that acts through dopamine rather than epinephrine, characteristic of reference catechol-O-meth
Autor:
Tim Wiltshire, Danielle Cunningham, Samantha K. Segall, Xia Wen, Carolina B. Meloto, Lisa M. Tarantino, Jeffrey S. Mogil, Svetlana A. Shabalina, Josee Gauthier, Sarasa Tohyama, Loren J. Martin, Luda Diatchenko
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. A functional mouse Comt allele, associated with pain behaviour, increases Comt expression by inserting an early polyadenylation signal and removing naturally occurring regulatory microRNA signals
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice
Autor:
Laura Grabowski-Boase, Samantha K. Segall, J. S. Marron, Lisa M. Tarantino, Tim Wiltshire, Andrea G. Nackley, William R. Lariviere, Gary D. Slade, Luda Diatchenko, Josee Gauthier, Thomas M. Maynard, Janice S. Bailey, Brian M. Steffy, X. Lu, J. R. Walker
Publikováno v:
Genes, Brain and Behavior. 9:933-946
Catechol-O-methyltransferase (COMT) is an ubiquitously expressed enzyme that maintains basic biologic functions by inactivating catechol substrates. In humans, polymorphic variance at the COMT locus has been associated with modulation of pain sensiti
Autor:
Luda Diatchenko, Nikolay V. Dokholyan, Erinn L. Acland, William Maixner, Loren J. Martin, Josee Gauthier, Marjo Piltonen, Marino Convertino, Jeffrey S. Mogil
Publikováno v:
The journal of pain. 16(12)
Recent efforts have suggested that the β-adrenergic receptor (β-AR) system may be a novel and viable therapeutic target for pain reduction; however, most of the work to date has focused on the β 2 -adrenergic receptor (AR). Here, we compared the a
Autor:
Inna E. Tchivileva, Svetlana A. Shabalina, Kyoko Shibata, Roland Staud, Inna Belfer, Margaret R. Wallace, Nikolay A. Spiridonov, Dmitri V. Zaykin, Aleksey Y. Ogurtsov, Carly Kiselycznyk, Luda Diatchenko, Pavel Gris, Mitchell B. Max, Josee Gauthier, William Maixner, Roger B. Fillingim, David Goldman, Bikashkumar Mishra
Publikováno v:
Human Molecular Genetics
The mu-opioid receptor (OPRM1) is the principal receptor target for both endogenous and exogenous opioid analgesics. There are substantial individual differences in human responses to painful stimuli and to opiate drugs that are attributed to genetic
Autor:
Yoon Park, Lynn D. Condreay, Marc G. Ghany, M. Farooq Khokhar, Mary C. Kuhns, Jay H. Hoofnagle, David Herion, D. Lau, David E. Kleiner, Josee Gauthier, T. Jake Liang, Edward Doo, Peter Schmid
Publikováno v:
Scopus-Elsevier
Lamivudine therapy induces improvements in chronic hepatitis B in a high proportion of patients, but prolonged therapy is limited by the development of viral resistance. We analyzed clinical responses and virologic resistance in 27 patients treated c