Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Iulian Pruteanu-Malinici"'
Autor:
Zheng Yan, Raphael Thierry, Antoine deWeck, Claire Fabre, Felipe Correa Geyer, Joel Wagner, Oleg Iartchouk, Jeffrey A. Engelman, Beverly Nguyen, Rohan Diwanji, James Deeds, Julie Chen, Quincey Simmons, Naiyan Chen, Viviana Cremasco, Jonathan Chang, Joseph X. Zhou, Matt Hims, Yenyen Yu, Shaobu Weng, Pushpa Jayaraman, Stephanie Schwartz, David A. Ruddy, Michelle Piquet, Vera M. Ruda, Nathaniel D. Kirkpatrick, Pavitra Chikkegowda, Mirek Dostalek, Iulian Pruteanu-Malinici, Brian Minie, Glenn Dranoff, Markus Riester, Marc Pelletier, Alina Raza, Angelo Grauel, Kenzie MacIsaac, Jincheng Wu, Tyler Laszewski
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Despite the increasing interest in targeting stromal elements of the tumor microenvironment, we still face tremendous challenges in developing adequate therapeutics to modify the tumor stromal landscape. A major obstacle to this is our poor understan
Autor:
Iulian Pruteanu-Malinici, Patricia Greninger, Wilhelm Haas, Cyril H. Benes, John D. Lapek, Robert Morris, Arnaud Amzallag
Publikováno v:
Nature biotechnology
The formation of protein complexes and the co-regulation of the cellular concentrations of proteins are essential mechanisms for cellular signaling and for maintaining homeostasis. Here we use isobaric-labeling multiplexed proteomics to analyze prote
Autor:
Simon F. Lacey, Eric Lancaster, Fang Chen, Edward A. Stadtmauer, Don L. Siegel, J. Joseph Melenhorst, Iulian Pruteanu-Malinici, Regina M. Young, Dan T. Vogl, Karen Dengel, Annemarie Nelson, Wei-Ting Hwang, Brendan M. Weiss, Adam D. Cohen, Bruce L. Levine, Alfred L. Garfall, Michael C. Milone, Carl H. June, Megan M. Davis, Jennifer Brogdon, Randi Isaacs, Gabriela Plesa
Publikováno v:
J Clin Invest
BACKGROUND. CAR T cells are a promising therapy for hematologic malignancies. B cell maturation antigen (BCMA) is a rational target in multiple myeloma (MM). METHODS. We conducted a phase I study of autologous T cells lentivirally transduced with a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5624fbd7933095116425e48e29e0cca6
https://europepmc.org/articles/PMC6546468/
https://europepmc.org/articles/PMC6546468/
Autor:
Lifeng Tian, Joseph A. Fraietta, Jun Xu, Hans Bitter, Carl H. June, Iulian Pruteanu-Malinici, Edward Pequignot, Alina C. Boesteanu, Roddy S. O’Connor, Changfeng Zhang, Noelle V. Frey, Corin L. Dorfmeier, F. Brad Johnson, Simon F. Lacey, Nicholas Wilcox, Bruce L. Levine, Sadik H. Kassim, Stefan Lundh, Harit Parakandi, E. John Wherry, Megan M. Davis, J. Joseph Melenhorst, Regina M. Young, David L. Porter, Wei-Ting Hwang, Yan Wang, Felipe Bedoya, Alexander C. Huang, David E Ambrose, Li Liu, Mercy Gohil, Jennifer Brogdon, Elena Orlando, Don L. Siegel, Fang Chen, Irina Kulikovskaya, Minnal Gupta
Tolerance to self-antigens prevents the elimination of cancer by the immune system1,2. We used synthetic chimeric antigen receptors (CARs) to overcome immunological tolerance and mediate tumor rejection in patients with chronic lymphocytic leukemia (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eab21abca5e0308fecf5fa6ee68f9d55
https://europepmc.org/articles/PMC6117613/
https://europepmc.org/articles/PMC6117613/
Autor:
Anthony R. Mato, Simon F. Lacey, Vijay Bhoj, Mariusz A. Wasik, Bruce L. Levine, David L. Porter, Stephen J. Schuster, Jennifer Brogdon, Daniel J. Landsburg, J. Joseph Melenhorst, Özlem Anak, Carl H. June, Elise A. Chong, Sunita D. Nasta, Jakub Svoboda, Iulian Pruteanu-Malinici
Patients with diffuse large B-cell lymphoma or follicular lymphoma that is refractory to or that relapses after immunochemotherapy and transplantation have a poor prognosis. High response rates have been reported with the use of T cells modified by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff5996afe498892576e3870afb19920
https://europepmc.org/articles/PMC5788566/
https://europepmc.org/articles/PMC5788566/