Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Chihiro Morishima"'
Autor:
Kunle Odunsi, Feng Qian, Amit A. Lugade, Han Yu, Melissa A. Geller, Steven P. Fling, Judith C. Kaiser, Andreanne M. Lacroix, Leonard D’Amico, Nirasha Ramchurren, Chihiro Morishima, Mary L. Disis, Lucas Dennis, Patrick Danaher, Sarah Warren, Van Anh Nguyen, Sudharshan Ravi, Takemasa Tsuji, Spencer Rosario, Wenjuan Zha, Alan Hutson, Song Liu, Shashikant Lele, Emese Zsiros, A. J. Robert McGray, Jessie Chiello, Richard Koya, Thinle Chodon, Carl D. Morrison, Vasanta Putluri, Nagireddy Putluri, Donald E. Mager, Rudiyanto Gunawan, Martin A. Cheever, Sebastiano Battaglia, Junko Matsuzaki
Publikováno v:
Sci Transl Med
To uncover underlying mechanisms associated with failure of indoleamine 2,3-dioxygenase 1 (IDO1) blockade in clinical trials, we conducted a pilot, window-of-opportunity clinical study in 17 patients with newly diagnosed advanced high-grade serous ov
Autor:
Jack O. Egan, Jeffrey S. Miller, Ann W. Silk, Martin A. Cheever, Hing C. Wong, Sylvia Lee, Steven P. Fling, Peter R. Rhode, Chihiro Morishima, Shernan G. Holtan, Andreanne M. Lacroix, Kim Margolin, Judith C Kaiser, Monica Brown Jones, Marc S. Ernstoff, Amy Rock, Vamsidhar Velcheti
Publikováno v:
Clinical Cancer Research. 24:5552-5561
Purpose: IL15 induces the activation and proliferation of natural killer (NK) and memory CD8+ T cells and has preclinical antitumor activity. Given the superior activity and favorable kinetics of ALT-803 (IL15N72D:IL15RαSu/IgG1 Fc complex) over reco
Autor:
Anu Chaudhary, Chihiro Morishima, Kimberly van Leuven, Anna Wald, Mark H. Wener, Tess Hendelman, Susan L. Fink, Erwin Berthier, Andrew N. Hoofnagle, Emily J. Welch, Brook A Quist, Jacqueline Chee, Angela Leclair
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0255841 (2021)
PLoS ONE
PLoS ONE
Background Efforts to minimize COVID-19 exposure during the current SARS-CoV-2 pandemic have led to limitations in access to medical care and testing. The Tasso-SST kit includes all of the components necessary for remote, capillary blood self-collect
Autor:
Michael R. Holbrook, Andrew Bryan, Christopher L. McClurkan, David M. Koelle, Anna Wald, Mark H. Wener, Lichen Jing, Janie Liang, Susan L. Fink, Stacy Selke, Chihiro Morishima, Elena Postnikova, Sarah A. McGuffin, Danniel Zamora, Adrienne E Shapiro, Marie K. Das, Anu Chaudhary, Alexander L. Greninger, Steven Mazur, Terry Gernsheimer, Vladimir V. Lukin, Jim Boonyaratanakornkit, Robin Gross, Victoria L. Campbell, Keith R. Jerome
Publikováno v:
The Journal of clinical investigation. 131(3)
BACKGROUNDSARS-CoV-2-specific antibodies may protect from reinfection and disease, providing rationale for administration of plasma containing SARS-CoV-2-neutralizing antibodies (nAbs) as a treatment for COVID-19. Clinical factors and laboratory assa
Autor:
Stephen A. Rawlings, Jeffrey R Strich, Richard T. Davey, Chihiro Morishima, Daniel S. Chertow, Sanchita Das, Jeffrey I. Cohen, Davey M. Smith, Peter D. Burbelo, Francis X. Riedo
Publikováno v:
medRxiv
medRxiv : the preprint server for health sciences, vol 1, iss 05-20
medRxiv : the preprint server for health sciences, vol 1, iss 05-20
BackgroundSARS-CoV-2, the cause of coronavirus disease 2019 (COVID-19), is associated with respiratory-related morbidity and mortality. Assays to detect virus-specific antibodies are important to understand the prevalence of infection and the course
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d9a76a5e56d98713aeab720bbf6338
Autor:
Chihiro Morishima, Lei Yu, Minjun C. Apodaca, Amy Wright, William P. Harris, Raymond S. Yeung, Angela M. Riggins
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Background Myeloid-derived suppressor cells (MDSC) have been found to play an important role in limiting immune responses in cancer. Higher circulating MDSC levels have been associated with greater tumor burden, poorer response to immunotherapy, and
Autor:
Carolyn Zanis, Gaelen K. Dwyer, Brenna C. Simons, Philip R. Spradling, Tammy L. Choromanski, Mary Snowball, Minjun C. Apodaca, Chihiro Morishima, Samantha Case, Cindy Knall, Michael G. Bruce, Dana J. T. Bruden, Susan Negus, Hazel D. Brogdon, Brian J. McMahon
Publikováno v:
Journal of Infectious Diseases. 214:273-280
Background. Long-lasting protection resulting from hepatitis B vaccine, despite loss of antibody against hepatitis B virus (HBV) surface antigen (anti-HBs), is undetermined. Methods. We recruited persons from a cohort vaccinated with plasma-derived h
Autor:
Chihiro Morishima, Gyongyi Szabo, Jules L. Dienstag, Deepa Naishadham, Elizabeth C. Wright, Anna S.F. Lok, Adrian M. Di Bisceglie, Marc G. Ghany, Karen L. Lindsay, Gregory T. Everson, Mitchell L. Shiffman, Timothy R. Morgan
Publikováno v:
American Journal of Gastroenterology. 107:1388-1398
During the Hepatitis C Antiviral Long-term Treatment against Cirrhosis Trial, 3.5 years of maintenance peginterferon-alfa-2a therapy did not affect liver fibrosis progression or clinical outcomes among 1,050 previous interferon nonresponders with adv
Autor:
Laura Q.M. Chow, Leslie N. Anderson, Mary L. Disis, Robert M. Hershberg, James Kyle Bryan, Keith D. Eaton, Bernardo H. L. Goulart, Kristi Manjarrez, Christina S. Baik, Renato G. Martins, Chihiro Morishima, Gregory N. Dietsch
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(10)
Purpose: As Toll-like receptors (TLR) are key mediators of immune responses, TLR agonists may be important for augmenting the efficacy of therapies for squamous cell carcinoma of the head and neck (SCCHN). Motolimod (VTX-2337), a selective small-mole
Autor:
Kelly G, Paulson, Christopher W, Lewis, Mary W, Redman, William T, Simonson, Aaron, Lisberg, Deborah, Ritter, Chihiro, Morishima, Kathleen, Hutchinson, Lola, Mudgistratova, Astrid, Blom, Jayasri, Iyer, Ata S, Moshiri, Erica S, Tarabadkar, Joseph J, Carter, Shailender, Bhatia, Masaoki, Kawasumi, Denise A, Galloway, Mark H, Wener, Paul, Nghiem
Publikováno v:
Cancer. 123(8)
Merkel cell carcinoma (MCC) is an aggressive skin cancer with a recurrence rate of40%. Of the 2000 MCC cases per year in the United States, most are caused by the Merkel cell polyomavirus (MCPyV). Antibodies to MCPyV oncoprotein (T-antigens) have bee