Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Archana Thakur"'
Publikováno v:
Indian Pediatrics. 59:636-642
The biggest-ever outbreak of monkeypox disease in non-endemic countries started in May, 2022. Though no monkeypox case has been reported from India, till mid-June, 2022, yet, considering the rate of spread to the non-endemic countries, there is an ur
Autor:
Jeffrey M. Sturek, Tania A. Thomas, James D. Gorham, Chelsea A. Sheppard, Allison H. Raymond, Kristen Petros De Guex, William B. Harrington, Andrew J. Barros, Gregory R. Madden, Yosra M. Alkabab, David Y. Lu, Qin Liu, Melinda D. Poulter, Amy J. Mathers, Archana Thakur, Dana L. Schalk, Ewa M. Kubicka, Lawrence G. Lum, Scott K. Heysell
Publikováno v:
medRxiv
RationaleThe COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an unprecedented event requiring rapid adaptation to changing clinical circumstances. Convalescent immune plasma (CIP) is a promising treatme
Autor:
Mien Sho, Sun K. Ho, Josue Samayoa, Hamsell M. Alvarez, Archana Thakur, Belinda Cairns, Mengli Xiong, Diane Hollenbaugh, Debra Chao, Yoshiko Akamatsu, Li Zhou, Enrico L. Digiammarino, Charles M. Forsyth, Melvin Fox, Siu sze Tan, Vivian Zhao, Zhenghai Xu, David B. Powers
Publikováno v:
Molecular Cancer Therapeutics. 19:1040-1051
CD137 (TNFRSF9, 4-1BB) agonist antibodies (mAb) have demonstrated potent antitumor activity with memory response while causing hepatotoxicity in mouse models. In clinical trials, the degrees of liver toxicity of anti-CD137 vary from grade 4 transamin
Autor:
Max S. Wicha, Runming Jin, Shiang Huang, Lawrence G. Lum, Qiao Li, Alfred E. Chang, Yalei Zhang, Ming Lin, Yangyang Hu, Elaine M. Hurt, Wenlong Shao, Archana Thakur, Yong Zhu, Shasha Ruan
Publikováno v:
Cancer Res
Integrin β4 (ITGB4) has been shown to play an important role in the regulation of cancer stem cells (CSC). Immune targeting of ITGB4 represents a novel approach to target this cell population, with potential clinical benefit. We developed two immuno
Autor:
John Scholler, Dana L Schalk, Lawrence G. Lum, Archana Thakur, Edwin T. Bliemeister, Ewa Kubicka, Carl H. June
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Adoptive T cell therapies for solid tumors is challenging. We generated metabolically enhanced co-activated-T cells by transducing intracellular co-stimulatory (41BB, ICOS or ICOS-27) and CD3ζ T cell receptor signaling domains followed by arming wit
Autor:
Anu Gulati, Aditi Das, Sandip Ray, Harish K Pemde, Ravitanya Sodani, Archana Thakur, Kaveri Pandit, Virendra Kumar, Abhijeet Saha, Sanya Chopra, Ankita Sharma, Preeti Singh, Dipti Kapoor
Publikováno v:
Journal of Tropical Pediatrics
Background Acute kidney injury (AKI) has been recognized as a significant risk factor for mortality among adults with severe acute respiratory syndrome coronavirus infection. Aim The aim of this study is to assess the prevalence and risk factors for
Autor:
Melissa Giroux, Vidya Kondadasula, Archana Thakur, Dana L Schalk, Zaid S. Al-Kadhimi, Kristie Fields, Patricia A. Steele, Abhinav Deol, Elyse Tomashewski, Lawrence E. Flaherty, Lawrence G. Lum, Qin Liu, Michael S. Simon
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundMetastatic human epidermal growth receptor II (HER2) negative breast cancer remains incurable. Our phase I study showed that anti-CD3 × anti-HER2 bispecific antibody armed activated T cells (HER2 BATs) may be effective against HER2-tumors.
Autor:
David A. Sieber, Marshall E. Kadin, William P. Adams, Lawrence G. Lum, Mark W. Clemens, Haiying Xu, John Morgan, Pat McGuire, Archana Thakur, Caroline A Glicksman
Publikováno v:
Aesthetic surgery journal. 41(12)
Background Granzyme B (GrB) is a serine protease secreted, along with pore-forming perforin, by cytotoxic lymphocytes to mediate apoptosis in target cells. GrB has been detected in tumor cells associated with systemic and breast implant–associated
Publikováno v:
The Journal of the Association of Physicians of India. 67(10)
Diabetes is one of the expensive diseases due to its chronic nature and gradual involvement of multiple organs, Moreover loss of economic productivity further enhances the cost of care. Several factors were reported to have impact on overall economic
Reduced susceptibility of carbapenem-resistant Klebsiella pneumoniae to biocides: An emerging threat
Publikováno v:
Indian Journal of Medical Microbiology, Vol 34, Iss 3, Pp 355-358 (2016)
Dealing with carbapenem-resistant Klebsiella pneumoniae (CR-Kp) strains, which are generally pan-drug resistant, is an uphill task for health care professionals. Owing to limited therapeutic options and the possibility of development of resistance to