Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Morris, D."'
Autor:
Anna Skakodub, Lisa M. DeAngelis, Morris D. Groves, Adrienne Boire, Jeffrey Raizer, Michelle E. Melisko, Suriya Jeyapalan, Rachna Malani, Priya Kumthekar, Andrew D. Seidman, Elena Pentsova, Andrew B. Lassman, Xuling Lin, Antonio Omuro, Nan Lin, Marc K. Rosenblum, Martin Fleisher
Publikováno v:
Journal of Neuro-Oncology
Purpose The CellSearch® system has been used to identify circulating tumor cells (CTCs) in cerebrospinal fluid (CSF) to diagnose leptomeningeal metastasis (LM) in patients with epithelial cancers. Using this system, we prospectively explored sequent
Autor:
Monica Loghin, W. K. Alfred Yung, Stefania Maraka, Marta Penas-Prado, Charles A. Conrad, John de Groot, Erik P. Sulman, Kenneth Aldape, Barbara O’Brien, Ivo W. Tremont-Lukats, Mark R. Gilbert, Kenneth R. Hess, Morris D. Groves, Aaron Mammoser, Vinay K. Puduvalli, Isaac Melguizo-Gavilanes
Publikováno v:
Cancer. 125:424-433
BACKGROUND: Repurposed memantine, mefloquine, and metformin have putative anticancer activity. The objective of this phase 1 study was to determine the maximum tolerated doses (MTDs) of combinations of these agents with temozolomide (TMZ). METHODS: A
Autor:
Steve Rosenfeld, Xiaolin Wang, Betty Lawrence, Mona Shing, Robert M. Fielding, Jean Paul Castaigne, Patrick Y. Wen, Christina A. Meyers, April F. Eichler, Eric T. Wong, Andrew Brenner, David Schiff, John Sarantopoulos, Jan Drappatz, Tom Mikkelsen, Morris D. Groves, Stephen M. Kelsey, Kelly Elian
Publikováno v:
Clinical Cancer Research. 19:1567-1576
Purpose: GRN1005 is a peptide–drug conjugate with the ability to penetrate the blood–brain barrier (BBB) and tumor cells by targeting the low-density lipoprotein receptor–related protein-1. We conducted a first-in-human phase I trial of GRN1005
Autor:
van Scheltinga, Af, Bakker, Sc, van Haren, Ne, Derks, Em, Buizer Voskamp, Je, Cahn, W, Ripke, S, Sanders, A, Kendler, K, Levinson, D, Sklar, P, Holmans, P, Lin, D., Duan, J, Ophoff, R, Andreassen, O, Scolnick, E, Cichon, S, St Clair, D, Corvin, A, Gurling, H, Werge, T, Rujescu, D, Blackwood, D, Pato, C, Malhotra, A, Purcell, S, Dudbridge, F, Neale, B, Rossin, L, Visscher, P, Posthuma, D, Ruderfer, D, Fanous, A, Stefansson, H, Steinberg, S, Mowry, B, Golimbet, V, Hert, De, M, Jonsson, E, Bitter, I, Pietilainen, O, Collier, D, Tosato, Sarah, Agartz, I, Albus, M, Alexander, M, Amdur, R, Amin, F, Bass, N, Bergen, S, Black, D, Børglum, A, Brown, M, Bruggeman, R, Buccola, N, Byerley, W, Cantor, R, Carr, V, Catts, S, Choudhury, K, Cloninger, C, Cormican, P, Craddock, N, Danoy, P, Datta, S, Haan, De, L, Demontis, D, Dikeos, D, Djurovic, S, Donnelly, P, Donohoe, G, Duong, L, Dwyer, S, Fink Jensen, A, Freedman, R, Freimer, N, Friedl, M, Georgieva, L, Giegling, I, Gill, M, Glenthøj, B, Godard, S, Hamshere, M, Hansen, M, Hansen, T, Hartmann, A, Henskens, F, Hougaard, D, Hultman, C, Ingason, A, Jablensky, A, Jakobsen, K, Jay, M, Jurgens, G, Kahn, R, Keller, M, Kenis, G, Kenny, E, Kim, Y, Kirov, G, Konnerth, H, Konte, B, Krabbendam, L, Krasucki, R, Lasseter, V, Laurent, C, Lawrence, J, Lencz, T, Lerer, F, Liang, K, Lichtenstein, P, Lieberman, J, Linszen, D, Lonnqvist, J, Loughland, C, Maclean, A, Maher, B, Maier, W, Mallet, J, Malloy, P, Mattheisen, M, Mattingsdal, M, Mcghee, K, Mcgrath, J, Mcintosh, A, Mclean, D, Mcquillin, A, Melle, I, Michie, P, Milanova, V, Morris, D, Mors, O, Mortensen, P, Moskvina, V, Muglia, P, Myin Germeys, I, Nertney, D, Nestadt, G, Nielsen, J, Nikolov, I, Nordentoft, M, Norton, N, Nothen, M, O'Dushlaine, C, Olincy, A, Olsen, L, O'Neill, F, Ørntoft, T, Owen, M, Pantelis, C, Papadimitriou, G, Pato, M, Peltonen, L, Petursson, H, Pickard, B, Pimm, J, Pulver, A, Puri, V, Quested, D, Quinn, E, Rasmussen, H, Rethelyi, Jm, Ribble, R, Rietschel, M, Riley, B, Ruggeri, Mirella, Schall, U, Schulze, T, Schwab, S, Scott, R, Shi, J, Sigurdsson, E, Silverman, J, Spencer, C, Stefansson, K, Strange, A, Strengman, E, Stroup, T, Suvisaari, J, Terenius, L, Thirumalai, S, Thygesen, J, Timm, S, Toncheva, D, van den Oord, E, van Os, J, van Winkel, R, Veldink, J, Walsh, D, Wang, A, Wiersma, D, Wildenauer, D, Williams, H, Williams, N, Wormley, B, Zammit, S, Sullivan, P, O'Donovan, M, Daly, M, Gejman, P), Ophoff, Ra, Kahn, Rs
Publikováno v:
Psychological Medicine, 43(12), 2563-2570. Cambridge University Press
Terwisscha van Scheltinga, A F, Bakker, S C, van Haren, N E, Derks, E M, Buizer-Voskamp, J E, Cahn, W, Ripke, S, Ophoff, R A, Posthuma, D & Kahn, R S 2013, ' Schizophrenia genetic variants are not associated with intelligence ', Psychological Medicine, vol. 43, no. 12, pp. 2563-2570 . https://doi.org/10.1017/S0033291713000196
BASE-Bielefeld Academic Search Engine
Van Scheltinga, A F T, Bakker, S C, Van Haren, N E M, Derks, E M, Buizer-Voskamp, J E, Cahn, W, Ripke, S, Ophoff, R A, Kahn, R S, Ripke, S, Sanders, A R, Kendler, K S, Levinson, D F, Sklar, P, Holmans, P A, Lin, D-Y, Duan, J, Ophoff, R A, Andreassen, O A, Scolnick, E, Cichon, S, St Clair, D, Corvin, A, Gurling, H, Werge, T, Rujescu, D, Blackwood, D H R, Pato, C N, Malhotra, A K, Purcell, S, Dudbridge, F, Neale, B M, Rossin, L, Visscher, P M, Posthuma, D, Ruderfer, D M, Fanous, A, Stefansson, H, Steinberg, S, Mowry, B J, Golimbet, V, De Hert, M, Jönsson, E G, Bitter, I, Pietiläinen, O P H, Collier, D A, Tosato, S, Agartz, I, Albus, M, Alexander, M, Amdur, R L, Amin, F, Bass, N, Bergen, S E, Black, D W, Børglum, A D, Brown, M A, Bruggeman, R, Buccola, N G, Byerley, W F, Cahn, W, Cantor, R M, Carr, V J, Catts, S V, Choudhury, K, Cloninger, C R, Cormican, P, Craddock, N, Danoy, P A, Datta, S, De Haan, L, Demontis, D, Dikeos, D, Djurovic, S, Donnelly, P, Donohoe, G, Duong, L T T, Dwyer, S, Fink-Jensen, A, Freedman, R, Freimer, N B, Friedl, M, Georgieva, L, Giegling, I, Gill, M, Glenthøj, B Y, Godard, S, Hamshere, M, Hansen, M, Hansen, T, Hartmann, A M, Henskens, F A, Hougaard, D M, Hultman, C M, Ingason, A, Jablensky, A V, Jakobsen, K D, Jay, M, Jürgens, G, Kahn, R S, Keller, M C, Kenis, G, Kenny, E, Kim, Y, Kirov, G K, Konnerth, H, Konte, B, Krabbendam, L, Krasucki, R, Lasseter, V K, Laurent, C, Lawrence, J, Lencz, T, Lerer, F B, Liang, K-Y, Lichtenstein, P, Lieberman, J A, Linszen, D H, Lönnqvist, J, Loughland, C M, Maclean, A W, Maher, B S, Maier, W, Mallet, J, Malloy, P, Mattheisen, M, Mattingsdal, M, McGhee, K A, McGrath, J J, McIntosh, A, McLean, D E, McQuillin, A, Melle, I, Michie, P T, Milanova, V, Morris, D W, Mors, O, Mortensen, P B, Moskvina, V, Muglia, P, Myin-Germeys, I, Nertney, D A, Nestadt, G, Nielsen, J, Nikolov, I, Nordentoft, M, Norton, N, Nöthen, M M, O'Dushlaine, C T, Olincy, A, Olsen, L, O'Neill, F A, Ørntoft, T F, Owen, M J, Pantelis, C, Papadimitriou, G, Pato, M T, Peltonen, L, Petursson, H, Pickard, B, Pimm, J, Pulver, A E, Puri, V, Quested, D, Quinn, E M, Rasmussen, H B, Réthelyi, J M, Ribble, R, Rietschel, M, Riley, B P, Ruggeri, M, Schall, U, Schulze, T G, Schwab, S G, Scott, R J, Shi, J, Sigurdsson, E, Silverman, J M, Spencer, C C A, Stefansson, K, Strange, A, Strengman, E, Stroup, T S, Suvisaari, J, Terenius, L T, Thirumalai, S, Thygesen, J H, Timm, S, Toncheva, D, Van Den Oord, E, Van Os, J, Van Winkel, R, Veldink, J, Walsh, D, Wang, A G, Wiersma, D, Wildenauer, D B, Williams, H J, Williams, N M A, Wormley, B, Zammit, S, Sullivan, P F, O'Donovan, M C, Daly, M J & Gejman, P V 2013, ' Schizophrenia genetic variants are not associated with intelligence ', Psychological Medicine, vol. 43, no. 12, pp. 2563-2570 . https://doi.org/10.1017/S0033291713000196
Psychological medicine, 43(12), 2563-2570. Cambridge University Press
Terwisscha van Scheltinga, A F, Bakker, S C, van Haren, N E, Derks, E M, Buizer-Voskamp, J E, Cahn, W, Ripke, S, Ophoff, R A, Posthuma, D & Kahn, R S 2013, ' Schizophrenia genetic variants are not associated with intelligence ', Psychological Medicine, vol. 43, no. 12, pp. 2563-2570 . https://doi.org/10.1017/S0033291713000196
BASE-Bielefeld Academic Search Engine
Van Scheltinga, A F T, Bakker, S C, Van Haren, N E M, Derks, E M, Buizer-Voskamp, J E, Cahn, W, Ripke, S, Ophoff, R A, Kahn, R S, Ripke, S, Sanders, A R, Kendler, K S, Levinson, D F, Sklar, P, Holmans, P A, Lin, D-Y, Duan, J, Ophoff, R A, Andreassen, O A, Scolnick, E, Cichon, S, St Clair, D, Corvin, A, Gurling, H, Werge, T, Rujescu, D, Blackwood, D H R, Pato, C N, Malhotra, A K, Purcell, S, Dudbridge, F, Neale, B M, Rossin, L, Visscher, P M, Posthuma, D, Ruderfer, D M, Fanous, A, Stefansson, H, Steinberg, S, Mowry, B J, Golimbet, V, De Hert, M, Jönsson, E G, Bitter, I, Pietiläinen, O P H, Collier, D A, Tosato, S, Agartz, I, Albus, M, Alexander, M, Amdur, R L, Amin, F, Bass, N, Bergen, S E, Black, D W, Børglum, A D, Brown, M A, Bruggeman, R, Buccola, N G, Byerley, W F, Cahn, W, Cantor, R M, Carr, V J, Catts, S V, Choudhury, K, Cloninger, C R, Cormican, P, Craddock, N, Danoy, P A, Datta, S, De Haan, L, Demontis, D, Dikeos, D, Djurovic, S, Donnelly, P, Donohoe, G, Duong, L T T, Dwyer, S, Fink-Jensen, A, Freedman, R, Freimer, N B, Friedl, M, Georgieva, L, Giegling, I, Gill, M, Glenthøj, B Y, Godard, S, Hamshere, M, Hansen, M, Hansen, T, Hartmann, A M, Henskens, F A, Hougaard, D M, Hultman, C M, Ingason, A, Jablensky, A V, Jakobsen, K D, Jay, M, Jürgens, G, Kahn, R S, Keller, M C, Kenis, G, Kenny, E, Kim, Y, Kirov, G K, Konnerth, H, Konte, B, Krabbendam, L, Krasucki, R, Lasseter, V K, Laurent, C, Lawrence, J, Lencz, T, Lerer, F B, Liang, K-Y, Lichtenstein, P, Lieberman, J A, Linszen, D H, Lönnqvist, J, Loughland, C M, Maclean, A W, Maher, B S, Maier, W, Mallet, J, Malloy, P, Mattheisen, M, Mattingsdal, M, McGhee, K A, McGrath, J J, McIntosh, A, McLean, D E, McQuillin, A, Melle, I, Michie, P T, Milanova, V, Morris, D W, Mors, O, Mortensen, P B, Moskvina, V, Muglia, P, Myin-Germeys, I, Nertney, D A, Nestadt, G, Nielsen, J, Nikolov, I, Nordentoft, M, Norton, N, Nöthen, M M, O'Dushlaine, C T, Olincy, A, Olsen, L, O'Neill, F A, Ørntoft, T F, Owen, M J, Pantelis, C, Papadimitriou, G, Pato, M T, Peltonen, L, Petursson, H, Pickard, B, Pimm, J, Pulver, A E, Puri, V, Quested, D, Quinn, E M, Rasmussen, H B, Réthelyi, J M, Ribble, R, Rietschel, M, Riley, B P, Ruggeri, M, Schall, U, Schulze, T G, Schwab, S G, Scott, R J, Shi, J, Sigurdsson, E, Silverman, J M, Spencer, C C A, Stefansson, K, Strange, A, Strengman, E, Stroup, T S, Suvisaari, J, Terenius, L T, Thirumalai, S, Thygesen, J H, Timm, S, Toncheva, D, Van Den Oord, E, Van Os, J, Van Winkel, R, Veldink, J, Walsh, D, Wang, A G, Wiersma, D, Wildenauer, D B, Williams, H J, Williams, N M A, Wormley, B, Zammit, S, Sullivan, P F, O'Donovan, M C, Daly, M J & Gejman, P V 2013, ' Schizophrenia genetic variants are not associated with intelligence ', Psychological Medicine, vol. 43, no. 12, pp. 2563-2570 . https://doi.org/10.1017/S0033291713000196
Psychological medicine, 43(12), 2563-2570. Cambridge University Press
BackgroundSchizophrenia is associated with lower pre-morbid intelligence (IQ) in addition to (pre-morbid) cognitive decline. Both schizophrenia and IQ are highly heritable traits. Therefore, we hypothesized that genetic variants associated with schiz
Autor:
Ava B. Plummer, Morris D. Groves
Publikováno v:
CONTINUUM: Lifelong Learning in Neurology. 18:421-425
Outcomes for patients with glioblastoma have improved with the addition of temozolomide (TMZ) chemotherapy to radiation therapy followed by adjuvant TMZ for up to 1 year. Patients often wish to continue chemotherapy after the standard 1-year course.
Autor:
Charles A. Conrad, Eric L. Chang, W. K. Alfred Yung, Kathy Hunter, John de Groot, Mark R. Gilbert, Morris D. Groves, Vinay K. Puduvalli, Howard Colman, S.Y. Woo, Kenneth R. Hess, Anita Mahajan, Victor A. Levin, Pierre Giglio, Javier Gonzalez
Publikováno v:
Neuro-Oncology
External beam radiation therapy (XRT) with concomitant temozolomide and 6 cycles of adjuvant temozolomide (5/28-day schedule) improves survival in patients with newly diagnosed glioblastoma compared with XRT alone. Studies suggest that dose-dense tem
Autor:
Christina A. Meyers, Victor A. Levin, W. K. Alfred Yung, Vivien Liu, Charles A. Conrad, Morris D. Groves, V. K. Puduvalli, Kathy Hunter, Kenneth R. Hess, Mark R. Gilbert
Publikováno v:
British Journal of Cancer
Background: Because of the poor outcomes for patients with recurrent glioblastoma multiforme (GBM), and some laboratory and clinical evidence of efficacy using interferon in GBM, we assessed the toxicity and efficacy of temozolomide (TMZ) combined wi
Autor:
Morris D. Groves, W. K. Alfred Yung, Vinay K. Puduvalli, Jeffrey S. Weinberg, Ta Jen Liu, Massimo Cristofanilli, Kenneth R. Hess, Charles A. Conrad, Howard Colman, Mark R. Gilbert
Publikováno v:
Journal of Neuro-Oncology. 94:229-234
Breast cancer, lung cancer and melanoma metastasize to the meninges in 5-15% of patients. The identification of specific biomarkers of disease may allow for earlier diagnosis and treatment. Preclinical evidence suggests the possible relevance of SDF-
Publikováno v:
Neuro-Oncology. 10:1010-1018
The purpose of this study was to describe a cohort of patients with leptomeningeal melanomatosis (LM) and to determine prognostic factors for outcomes in these patients. The primary hypothesis was that more extensive burden of CNS metastasis at the t
Autor:
Sandra Ictech, Charles A. Conrad, Edward F. Jackson, Victor A. Levin, Vinay K. Puduvalli, John de Groot, Pierre Giglio, Sigmund Hsu, Howard Colman, Kenneth R. Hess, Morris D. Groves, Srikanth Mahankali, Melesa G. Ritterhouse, Mark R. Gilbert, W. K. Alfred Yung
Publikováno v:
Neuro-Oncology. 10:216-222
Glioblastoma multiforme (GBM) is associated with significant morbidity and a disproportionately high rate of mortality. For patients with newly diagnosed GBM, chemoradiation therapy followed by adjuvant treatment with temozolomide provides a survival