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Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Autor:
Sanjiv Lakhanpal, Zoe K. Deol, Peter J. Pappas, Theresa Soto, Richard Kennedy, Gaurav Lakhanpal
Publikováno v:
Journal of Vascular Surgery: Venous and Lymphatic Disorders. 10:342-347
Background The use of iliac vein stenting for the treatment of pelvic pain secondary to pelvic venous insufficiency has significantly increased. In women of childbearing age, the effect of the gravid uterus on stent function and patency is unclear. T
Autor:
Luisa Castro-Laria, Ana M. Sánchez-Migallón, David Busquets, Ana Echarri, Maria Esteve, Federico Argüelles-Arias, R. Vicente, José María Huguet, María Dolores Martín-Arranz, D Ceballos, Francesc Casellas, Jordina Llaó, for Rapida trial investigators, M Navarro-Llavat, Ignacio Marín-Jiménez, Manuel Barreiro-de Acosta, Santiago García-López, José Miguel Boudet, Gema Díaz
Publikováno v:
Gastroenterología y Hepatología (English Edition). 45:165-176
No studies evaluating the rapidity of response to biological therapies are available for Crohn's disease (CD). The aim of this study was to evaluate rapidity of onset of clinical response and impact on quality of life (QoL) of adalimumab therapy in a
Publikováno v:
J Vasc Surg
OBJECTIVE: Opioid use is common among patients with peripheral arterial disease (PAD), given that pain is a defining symptom. Unfortunately, long-term opioid use places patients at dramatically increased risk of overdose and death. Although surgical
Autor:
Ichiro Kajiwara, Naritsugu Sakaino, Yasuhiro Izumiya, Kenichi Tsujita, Koichi Kaikita, Yasuhiro Nagayoshi, Kenji Sakamoto, Kazuteru Fujimoto, Jun Hokamaki, Shuichi Oshima, Takuhiro Shirakawa, Hideki Maruyama, Eiichiro Yamamoto, Nobuyasu Yamamoto, Koichi Kikuta, Ryusuke Tsunoda, Hideki Shimomura, Toshiyuki Matsumura, Koichiro Fujisue, Shunichi Koide, Nobutaka Hirai, Toyoki Hirose, Tomohiro Sakamoto, Shinichi Nakamura, Hisao Ogawa, Koichi Nakao, Shinji Tayama, Seiji Hokimoto, Invitation study investigators
Publikováno v:
Journal of Atherosclerosis and Thrombosis. 29:229-241
Aim Matrix metalloproteinases (MMPs) play critical roles in acute myocardial infarction (AMI). This trial was conducted to determine the potential effects of higher-dose rosuvastatin on circulating MMP levels in patients with AMI. Methods This was a
Publikováno v:
American Journal of Roentgenology. 218:351-358
Please see the Editorial Comment by Javier Villanueva-Meyer discussing this article. Background: Pegfilgrastim administration after chemotherapy increases bone marrow and spleen FDG uptake. Consens...
Autor:
Masayuki Takeda, Tomohide Tamura, Kohei Akiyoshi, Masahiro Morise, Naofumi Shinagawa, Toshiaki Saeki, Naoki Inui, Morihito Okada, Shunichi Sugawara, Kaoru Kubota, Yasutaka Watanabe, Akito Hata, Isamu Okamoto
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(2)
PURPOSE We evaluated the efficacy and safety of fosnetupitant (FosNTP) versus fosaprepitant (FosAPR) for preventing highly emetogenic chemotherapy-induced nausea and vomiting. This phase III study was the first head-to-head comparison between two dif
Autor:
Guofan Xu, Lei Feng, Hun Ju Lee, Michelle Avellaneda, Preetesh Jain, Linghua Wang, Luis Fayad, Omar Moghrabi, L. Jeffrey Medeiros, Cezar Iliescu, Nathan Fowler, Shuangtao Zhao, Yang Liu, Selvi Thirumurthi, Michael L. Wang, Chi Young Ok, Maria Badillo, Lucy Navsaria, Graciela M. Nogueras González, David Santos, Christopher R. Flowers, Francisco Vega, Guilin Tang, Holly Hill, Rashmi Kanagal-Shamanna, Fredrick B. Hagemeister, Yixin Yao
Publikováno v:
J Clin Oncol
PURPOSE Most patients with mantle cell lymphoma (MCL) are older. In this study, we investigated the efficacy and safety of a chemotherapy-free combination with ibrutinib and rituximab (IR) in previously untreated older patients with MCL (age ≥ 65 y
Autor:
Jerry A. Shields, Maura Di Nicola, Basil K. Williams, Jing Hua, Arman Mashayekhi, Carol L. Shields, Vladislav P. Bekerman
Publikováno v:
Ophthalmology Retina. 6:80-88
Purpose To report the efficacy of photodynamic therapy (PDT) for management of retinal hemangioblastoma. Design Retrospective case series. Participants Seventeen patients with retinal hemangioblastoma treated with PDT. Methods The medical records of
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Scientific Reports
Scientific Reports
Real-world data comparing the effectiveness of various glucagon-like peptide 1 receptor agonists (GLP-1 RAs) in type 2 diabetes mellitus (T2DM) are limited. We investigated the clinical effectiveness of liraglutide and dulaglutide in Japanese T2DM in