Zobrazeno 1 - 10
of 1 684
pro vyhledávání: '"35"'
Autor:
Masakazu Kinoshita, J. Javier Meana, Toshio Ota, Luis F. Callado, Yuji Odagaki, Jesús A. García-Sevilla
Publikováno v:
European journal of pharmacology. 764
By means of guanosine-5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS) binding assay combined with immunoprecipitation using anti-Gα subunit antibody, we recently reported 5-HT2A receptor- and M1 muscarinic acetylcholine receptor-mediated Gαq activ
Autor:
David Finkelstein, Kenneth E. Thummel, Amarjit S. Chaudhry, Sarah C. Sim, Eleni Aklillu, Shuoguo Wang, Alison E. Fohner, Bhagwat Prasad, Yoshiyuki Shirasaka, Erin G. Schuetz, Gang Wu, Yiping Fan
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 43(8)
CYP2C19 rs12769205 alters an intron 2 branch point adenine leading to an alternative mRNA in human liver with complete inclusion of intron 2 (exon 2B). rs12769205 changes the mRNA reading frame, introduces 87 amino acids, and leads to a premature sto
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 34:193-200
The pharmacokinetics of Tramadol and Promethazine after a single dose of 40, 80 and 120 mg intramuscular injecting CTHI was evaluated in healthy volunteers. Physical exam, vital signs, clinical laboratory tests and electrocardiogram measurements were
Autor:
Sang Joon Shin, Jae Kyung Roh, Sung Hoon Noh, Sun Young Rha, Hyun Cheol Chung, Hei Cheul Jeung, Joong Bae Ahn
Publikováno v:
Japanese Journal of Clinical Oncology
Objective: In this study, we compared the pharmacokinetic profiles of 5-fluorouracil (5-FU), tegafur, 5-chloro-2,4-dihydroxypyridine (CDHP) and potassium oxonate (Oxo) after administration of S-1 at 35 or 40 mg/m 2 bid for 28 consecutive days, in Cyc
Publikováno v:
Psychopharmacology
Rationale Previous research suggests that sleep polysomnography and EEG endpoints can be used to assess GABAergic activity; however, the impact of GABAB receptor positive allosteric modulators on sleep endpoints remains unclear. Objectives This phase
Publikováno v:
Fundamental & Clinical Pharmacology
Fundamental & Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2021, 35 (4), pp.645-649. ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
Fundamental and Clinical Pharmacology, Wiley, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, 2020, Online ahead of print. ⟨10.1111/fcp.12639⟩
Fundamental & Clinical Pharmacology, Wiley, 2020, ⟨10.1111/fcp.12639⟩
International audience; Rodent models of depression are useful for the investigation of cellular and neuronal mechanisms of antidepressant drugs and for the discovery of potential new targets. In this study, we examined the antidepressant-like effect
Autor:
Carol J. Boyd, Sean Esteban McCabe, Philip Veliz, Vita V. McCabe, Ty S. Schepis, John E. Schulenberg
Publikováno v:
Drug and Alcohol Dependence. 194:377-385
Background This longitudinal study assesses characteristics associated with adolescents’ nonmedical use of prescription opioids (NMUPO) including: frequency, co-ingestion, motives, specific opioid type; sequence of initiation of medical use of pres
Autor:
Mao-Mao Shi, Tian-Pu Cheng, Ying-Qi Xu, Michael J. Quon, Zhi-Jun Ou, Xi Zhang, Chen Liu, Chun-Xiang Zhang, Yu-Peng Jian, Hua-Ming Li, Zhi-Ping Wang, Zhe Xu, Xiang Liu, Yan Li, Zhen-Qing Wang, Jing-Song Ou, Li Zhou, Wen Zhang
Publikováno v:
Journal of Cardiovascular Pharmacology. 72:176-185
Simvastatin treatment is cardioprotective in patients undergoing noncoronary artery cardiac surgery. However, the mechanisms by which simvastatin treatment protects the myocardium under these conditions are not fully understood. Seventy patients unde
Publikováno v:
Journal of Psychopharmacology, 35(12), 1449-1463. Sage Publications Ltd
Journal of Psychopharmacology (Oxford, England)
Journal of Psychopharmacology, 35(12):02698811211044679, 1449-1463. SAGE Publications Ltd
Journal of Psychopharmacology (Oxford, England)
Journal of Psychopharmacology, 35(12):02698811211044679, 1449-1463. SAGE Publications Ltd
Background: Acute stress is thought to reduce goal-directed behaviour, an effect purportedly associated with stress-induced release of catecholamines. In contrast, experimentally increased systemic catecholamine levels have been shown to increase goa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a79756d0a64820c767828e2714ddef
https://research.tilburguniversity.edu/en/publications/46a1e6c6-3347-43aa-b047-bc843c226d35
https://research.tilburguniversity.edu/en/publications/46a1e6c6-3347-43aa-b047-bc843c226d35
Autor:
Keji Chen, Yan-Ming Xie, Yan Chai, Junxia Li, Jun Li, Ping Yao, Lian-Xin Wang, Yumiao Gong, Zehuai Wen, Mei Xue, Yanling Zhang, Weihui Lyu, Jian Lyu
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 81
Salvia Miltiorrhiza Depside Salt (SMDS) was extracted from Salvia miltiorrhiza with high-quality control of active principles. In 2005, China's FDA approved the use of SMDS for stable angina pectoris (SAP), but the evidence of SMDS combined with aspi