Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David F. Claxton"'
Autor:
Elisabeth Paietta, Zhuoxin Sun, Martin S. Tallman, Neil E. Kay, Natalie S. Callander, Sanford Kempin, Rhett P. Ketterling, Gordan Srkalovic, David F. Claxton, Gerald Gross, Joseph J. Mazza, Olga Frankfurt, Joel N. Saltzman
Publikováno v:
Acta Haematol
Patients with relapsed/refractory (R/R) chronic lymphocytic leukemia (CLL) may benefit from salvage chemoimmunotherapy (CIT). To explore further the use of CIT in the pre-novel agent era, ECOG-ACRIN undertook a phase 2 trial (E2903) for R/R CLL utili
Autor:
Amit Verma, Selina M. Luger, Zhuoxin Sun, Puneet S. Cheema, Jaroslaw P. Maciejewski, Martin S. Tallman, Mark R. Litzow, David F. Claxton, Jessica K. Altman, Rami S. Komrokji, John M. Bennett, Alan F. List, Kathy L. McGraw, Ryan J. Mattison, Charles A. Schiffer, Andrew S. Artz, Timothy R. Wassenaar
Publikováno v:
J Clin Oncol
PURPOSE Impaired response to erythropoietin underlies ineffective erythropoiesis and anemia in myelodysplastic syndromes (MDS). We investigated whether treatment with lenalidomide (LEN), which augments erythropoietin receptor signaling in vitro, can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b527e937e93c76976bde4e0ca2a12342
https://europepmc.org/articles/PMC8274743/
https://europepmc.org/articles/PMC8274743/
Autor:
Todd E. Fox, Mark Kester, Hong Gang Wang, Shantu Amin, Charyguly Annageldiyev, Gemma Fabriàs, Jennifer M. Pearson, David J. Feith, Dhimant Desai, Thomas P. Loughran, José Luis Abad, Su Fern Tan, Myles C. Cabot, David F. Claxton, Arati Sharma
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Mol Cancer Res
instname
Mol Cancer Res
Acute myeloid leukemia (AML) is a disease characterized by uncontrolled proliferation of immature myeloid cells in the blood and bone marrow. The 5-year survival rate is approximately 25%, and recent therapeutic developments have yielded little survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1bdd7205bbbd915f8f5818c777254c
http://hdl.handle.net/10261/212229
http://hdl.handle.net/10261/212229
Autor:
Raoul Tibes, Stan Gill, Chaofeng Liu, Christoph Röllig, Stephen A. Strickland, Joseph G. Jurcic, Stuart L. Goldberg, Maria R. Baer, Alexander E. Perl, Alexander I. Spira, Andreas Neubauer, Gary J. Schiller, Mark R. Litzow, Richard A. Larson, Catherine C. Smith, Jessica K. Altman, Harry P. Erba, Mark J. Levis, Erkut Bahceci, Giovanni Martinelli, Robert K. Stuart, Eunice S. Wang, Jorge E. Cortes, David F. Claxton, Celalettin Ustun, Ellen K. Ritchie
Publikováno v:
The Lancet. Oncology, vol 18, iss 8
The Lancet. Oncology
The Lancet. Oncology
Summary Background Internal tandem duplication mutations in FLT3 are common in acute myeloid leukaemia and are associated with rapid relapse and short overall survival. The clinical benefit of FLT3 inhibitors in patients with acute myeloid leukaemia
Publikováno v:
Leukemialymphoma. 59(10)
Acute respiratory complications occur frequently during the early phase of acute myeloid leukemia (AML) but information on the most severe form, acute respiratory distress syndrome (ARDS), is lacking. We retrospectively analyzed 280 patients with new
Autor:
Hong Gang Wang, Christopher M. Dower, Kenichiro Doi, Qiang Liu, Shen Shu Sung, Krishne Gowda, David F. Claxton, Shantu Amin, Jyh Ming Lin, Thomas P. Loughran
Publikováno v:
Cancer Biology & Therapy. 15:1688-1699
Mcl-1, a pro-survival member of the Bcl-2 protein family, is an attractive target for cancer therapy. We have recently identified the natural product marinopyrrole A (maritoclax) as a novel small molecule Mcl-1 inhibitor. Here, we describe the struct
Autor:
Jong K. Yun, Dhimant Desai, Brian M. Barth, Thomas P. Loughran, Andy Awwad, Mark Kester, Hong Gang Wang, Stephen D. Turner, Xin Liu, Samy A.F. Morad, Edward H. Schuchman, Kenichiro Doi, David J. Feith, Arati Sharma, Ross L. Levine, Junjia Zhu, Todd E. Fox, Su Fern Tan, Alden Dewey, Myles C. Cabot, David F. Claxton, Barbara Spitzer, Mithun Vinod Shah, Shantu Amin, Jason Liao
Publikováno v:
Oncotarget
// Su-Fern Tan 1 , Xin Liu 2 , Todd E. Fox 3 , Brian M. Barth 4 , Arati Sharma 2 , Stephen D. Turner 5 , Andy Awwad 2 , Alden Dewey 2 , Kenichiro Doi 6 , Barbara Spitzer 7 , Mithun Vinod Shah 8 , Samy A.F. Morad 9, 10 , Dhimant Desai 11 , Shantu Amin
Autor:
Sriram S. Shanmugavelandy, Brian M. Barth, Thomas P. Loughran, James M. Kaiser, Trevor M. Goff, Nicole A. DiVittore, David F. Claxton, Christopher O. McGovern, James H. Adair, Erhan I. Altinoglu, Mark Kester, Daniza Crespo-Gonzalez, Nicole R. Keasey
Publikováno v:
ACS Nano. 5:5325-5337
Leukemia is one of the most common and aggressive adult cancers, as well as the most prevalent childhood cancer. Leukemia is a cancer of the hematological system and can be divided into a diversity of unique malignancies based on the onset of the dis
Autor:
Dima Abi-Said, Sergio Giralt, Ira Braunschweig, Michael Andreeff, Issa F. Khouri, Naoto T. Ueno, Richard E. Champlin, Paolo Anderlini, Samer Bibawi, Borje S. Andersson, Elihu H. Estey, Luis Fayad, Koen van Besien, David F. Claxton, M. Donato, Rakesh Mehra, Donna Przepiorka, James Gajewski
Publikováno v:
American Journal of Hematology. 67:227-233
Sixty-two adults underwent marrow or blood stem cell transplantation from an HLA-matched related donor using high-dose thiotepa, busulfan, and cyclophosphamide (TBC) as the preparative regimen for treatment of advanced myelodysplastic syndrome (MDS)
Autor:
Martin H. Nguyen, Saroj Vadhan-Raj, L. Jeffrey Medeiros, Hagop M. Kantarjian, David F. Claxton, Carlos E. Bueso-Ramos, Di Lu, Weiqiang Zhao
Publikováno v:
The American journal of surgical pathology. 30(11)
The inv(16)(p13q22) or, less commonly the t(16;16)(p13;q22), is characteristic of acute myeloid leukemia (AML) with abnormal bone marrow eosinophils, also known as AML-M4Eo. This abnormality creates a fusion gene, 5' core binding factor beta (CBF-bet