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Autor:
Sonia Christian, Pritesh R. Patel, Karen Sweiss, Damiano Rondelli, John G. Quigley, Annie Lee Oh, Santosh L. Saraf, Ardaman Shergill, Arkadiusz Z. Dudek, Kelley Elizabeth Kozma, Irum Khan, Stephanie Barath, David Peace
Publikováno v:
Blood. 132:5218-5218
Background: Omacetaxine mepesuccinate (OM) is a semi-synthetic form of Homoharringtonine (HH), a cephalotaxine alkaloid. OM induces cell apoptosis by inhibiting peptide bond formation during mRNA translation, with rapid loss of short-lived proteins,