Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wendie N. Marks"'
Autor:
John G. Howland, Stuart M. Cain, Terrance P. Snutch, Quentin Greba, Wendie N. Marks, Nadine K. Zabder
Publikováno v:
The European journal of neuroscienceREFERENCES. 50(6)
Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are a rodent model of childhood absence epilepsy (CAE) that display a gain-of-function mutation in the gene encoding the Cav3.2 T-type calcium channel. GAERS demonstrate heightened learning and de
T-type calcium channels regulate the acquisition and recall of conditioned fear in male, Wistar rats
Publikováno v:
Behavioural Brain Research. 393:112747
The T-type calcium channel blocker, Z944, has been used as a pharmacological tool to assess T-type calcium channel function and examined for use as an anti-epileptic. As Z944 affects fear learning and memory in a rodent model of absence epilepsy, it
Autor:
Wendie N. Marks, Lisa E. Kalynchuk
Publikováno v:
Physiologybehavior. 182
Repeated exposure to high levels of stress hormones can enhance contextual and discrete fear conditioning in rats. A common belief is that this enhanced fear memory is largely mediated by the amygdala because both contextual and discrete fear conditi
Autor:
Quentin Greba, Wendie N. Marks, Terrance P. Snutch, Stuart M. Cain, John G. Howland, Mary E. Cavanagh
Publikováno v:
The European journal of neuroscience. 43(1)
Behavioural, neurological, and genetic similarities exist in epilepsies, their psychiatric comorbidities, and various psychiatric illnesses, suggesting common aetiological factors. Rodent models of epilepsy are used to characterize the comorbid sympt
Publikováno v:
Neuroscience. 289
Chronic exposure to the stress hormone corticosterone (CORT) is known to alter plasticity within hippocampal and amygdalar circuits that mediate fear learning and memory. The purpose of this experiment was to clarify the effects of chronic CORT on Pa
Autor:
Axel Guskjolen, April L. Lussier, Justin J. Botterill, Neil M. Fournier, Lisa E. Kalynchuk, Wendie N. Marks
Publikováno v:
Neuroscience. 265
Amygdala kindling is well known to increase unconditioned fear and anxiety. However, relatively little is known about whether this form of kindling causes functional changes within the neural circuitry that mediates fear learning and the retrieval of
Publikováno v:
Experimental neurology. 244
Epileptic seizures increase the birth of new neurons in the adult hippocampus. Although the consequences of aberrant neurogenesis on behavior are not fully understood, one hypothesis is that seizure-generated neurons might form faulty circuits that d