Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bryan Au"'
Autor:
Caren Furlonger, Alexandra Berger, Jessa Trentadue, Joshua M. Moreau, Christopher J. Paige, Jeffrey A. Medin, Makoto Yoshimitsu, Bryan Au, Shaalee Dworski
Publikováno v:
Haematologica. 100:e162-e165
Acid ceramidase (ACDase) is ubiquitous and catalyzes the degradation of ceramide. ACDase and ceramides have been implicated in many disorders, including cancer, obesity, diabetes, inflammation, and neurodegenerative diseases.[1][1]–[3][2] Deficienc
Autor:
Stéphane Carpentier, Virginie Garcia, Bryan Au, Josefina Casas, Thierry Levade, Razqallah Hakem, James C.M. Wang, Gemma Fabriàs, Kevin N. Kirouac, Calogera M. Simonaro, Patricia V. Turner, Mathilde J. Exertier, Zi Jian Xiong, Samah El‐Ghamrasni, Jeffrey A. Medin, Abdulfatah Alayoubi, Edward H. Schuchman, Gilbert G. Privé, Shaalee Dworski
Publikováno v:
EMBO Molecular Medicine
Farber disease (FD) is a severe inherited disorder of lipid metabolism characterized by deficient lysosomal acid ceramidase (ACDase) activity, resulting in ceramide accumulation. Ceramide and metabolites have roles in cell apoptosis and proliferation
Autor:
Toshihiro Takenaka, Makoto Yoshimitsu, Alexandra Berger, Shaalee Dworski, Bryan Au, Jessa Forster, James C.M. Wang, Caren Furlonger, Jeffrey A. Medin, Christopher J. Paige, Abdulfatah Alayoubi
Publikováno v:
Molecular Genetics and Metabolism. 108:S36
Autor:
Stéphane Carpentier, Shaalee Dworski, Thierry Levade, James C.M. Wang, Virginie Garcia, Jeffrey A. Medin, Razq Hakem, Abdu Alayoubi, Bryan Au, Samah El-Ghmrsni
Publikováno v:
Molecular Genetics and Metabolism. 105:S16
these two groups, those with HCT did better than ERT. Conclusion: With the exception of slight increased risk for hydrocephalus/shunt in the attenuated group, similar patterns of disease were found. Adaptive functions were better in the HCT group. Ea