Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Richard Appleton"'
Autor:
Elizabeth Lee, Anand Iyer, Amy Humphreys, Carrol Gamble, Richard Appleton, Helen Hickey, Joanne Noblet, Mark D Lyttle, Shrouk Messahel, Louise Roper, Naomi Rainford, Kerry Woolfall
Publikováno v:
EMERGENCY MEDICINE JOURNAL
Emergency Medicine Journal : EMJ
Emergency Medicine Journal : EMJ
BackgroundAlternatives to prospective informed consent enable the conduct of paediatric emergency and critical care trials. Research without prior consent (RWPC) involves practitioners approaching parents after an intervention has been given and seek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a727f999e78c76003e129ffed6ea530
Autor:
Mark D Lyttle, Amy Humphreys, Shrouk Messahel, Joanne Noblet, Helen Hickey, Anand Iyer, Richard Appleton, Elizabeth Lee, Naomi Rainford, Kerry Woolfall, Carrol Gamble, Louise Roper
Publikováno v:
Emergency Medicine Journal : EMJ
Emergency Medicine Journal
Emergency Medicine Journal
BackgroundKey challenges to the successful conduct of The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE) trial were identified at the pre-trial stage. These included practitioner anxieties about conduc
Autor:
Richard Appleton, Lyttle, Louise Roper, Kerry Woolfall, Helen Hickey, Amy Humphreys, Shrouk Messahel, Carrol Gamble
Publikováno v:
ASSOCIATION OF PAEDIATRIC EMERGENCY MEDICINE.
Aims Challenges to the success of ‘The Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children (EcLiPSE)’ trial included: practitioner anxieties about research without prior consent (‘deferred consent’), includin
Autor:
Helen Hickey, Amy Humphreys, Elizabeth Lee, Anand Iyer, Joanne Noblet, Shrouk Messahel, Mark D Lyttle, Carrol Gamble, Richard Appleton, Louise Roper, Naomi Rainford, Kerry Woolfall
Publikováno v:
TRIALS
Trials, Vol 20, Iss 1, Pp 1-14 (2019)
Trials
Trials, Vol 20, Iss 1, Pp 1-14 (2019)
Trials
Background EcLiPSE (Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus in children) is a randomised controlled trial (RCT) in the United Kingdom. Challenges to success include the need to immediately administer an intervention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c55a6f7e1fa04acad553ac77f796ad7
Autor:
Angus Dawson, Frances C Sherratt, Bridget Young, Paul S. McNamara, Carrol Gamble, Richard Appleton, Esther Crawley, Kerry Woolfall, Lucy Frith, Louise Roper
Publikováno v:
Association of Paediatric Emergency Medicine.
Aims Variations from informed consent (known as deferred consent or research without prior consent-RWPC) enable paediatric critical care research to proceed by allowing consent to be sought after a child has received an investigational intervention.
Autor:
Thomas Jaki, Timothy Martland, Anthony G Marson, J. Helen Cross, Lisa V. Hampson, Graeme J. Sills, Ian Wadsworth, Richard Appleton, Ailsa McLellan, John M. Pellock, Philip E. M. Smith
Publikováno v:
CNS Drugs
CNS DRUGS
CNS DRUGS
Data from clinical trials in adults, extrapolated to predict benefits in paediatric patients, could result in fewer or smaller trials being required to obtain a new drug licence for paediatrics. This article outlines the place of such extrapolation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05990a6246b7fbfa34af895f4050c6e1
https://eprints.gla.ac.uk/177176/1/177176.pdf
https://eprints.gla.ac.uk/177176/1/177176.pdf
Autor:
Richard Appleton, Anand Iyer
Publikováno v:
Seizure. 22:433-437
Purpose To survey the current transitional epilepsy services in tertiary paediatric neurology centres in the UK within the principles of transitional care for young people with epilepsy. Methods An online web-based questionnaire was sent to the lead
Publikováno v:
Anaesthesia. 66:409-414
Publikováno v:
Seizure. 15:307-312
Summary Objective Guidelines have been published recently on when an electroencephalogram (EEG) should be undertaken and the expected waiting time for a routine EEG, but have not included recommendations on how an EEG should be undertaken or who shou
Publikováno v:
Epilepsia. 55
Summary Transition is a purposeful, planned process that addresses the medical, psychosocial, educational, and vocational needs of adolescents and young adults with chronic medical conditions, as they advance from a pediatric and family-centered to a