Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sock Hoai Chan"'
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rend
Externí odkaz:
https://doaj.org/article/c63732b2d27a4a86a9c0d7a20529368c
Autor:
Sonia Davila, Sylvia Kam, Saumya Shekhar Jamuar, Khung Keong Yeo, Jyn Ling Kuan, Nicolas Bertin, Patrick Tan, Steve Rozen, Bin Tean Teh, Geoffrey S. Ginsburg, Jing Xian Teo, Cheng Xi Yang, Koei Wan Tham, Stuart A. Cook, Lori A. Orlando, Weng Khong Lim, Yasmin Bylstra, Sock Hoai Chan, R. Ryanne Wu
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Genome Medicine
Genome Medicine
Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rendering the
Autor:
Soo-Chin Lee, Weng Khong Lim, Zoe Li Ting Ang, Arun Mouli Kolinjivadi, Diana Ishak, Jianbang Chiang, Sock Hoai Chan, Haresh Sankar, Tarryn Shaw, Jing Xian Teo, Eliza Courtney, Siao Ting Chong, Marie Loh, Hui-Yuan Yeh, Joanne Ngeow, Li Zhou, Shao-Tzu Li
Publikováno v:
International journal of cancerREFERENCES. 148(3)
Identification of ancestry-specific pathogenic variants is imperative for diagnostic, treatment, management and prevention strategies, and to understand penetrance/modifiers on risk. Our study aimed to determine the clinical significance of a recurre
Autor:
Michaela Su-Fern Seng, Prasad Iyer, Mei Yoke Chan, Kenneth Tou En Chang, Nur Diana Binte Ishak, Joanne Ngeow, Tarryn Shaw, Enrica Ee Kar Tan, Jing Xian Teo, Weng Khong Lim, Sheng Hui Tan, Shao-Tzu Li, Ah Moy Tan, Yong Chen, Sharon Y.Y. Low, Sock Hoai Chan, Amos Hong Pheng Loh, Winston Chew, Shui Yen Soh
Publikováno v:
NPJ Genomic Medicine
npj Genomic Medicine, Vol 3, Iss 1, Pp 1-8 (2018)
npj Genomic Medicine, Vol 3, Iss 1, Pp 1-8 (2018)
Assessment of cancer predisposition syndromes (CPS) in childhood tumours is challenging to paediatric oncologists due to inconsistent recognizable clinical phenotypes and family histories, especially in cohorts with unknown prevalence of germline mut
Autor:
Stephen E Lincoln, Jennifer Fulbright, Scott T. Michalski, Joseph Wee, Marie Met-Domestici, Cedric Ng Chuan Young, Karen Vikstrom, Bin Tean Teh, Weng Khong Lim, Edward D. Esplin, Kesavan Sittampalam, Mohamad Farid, Sock Hoai Chan, Jing Quan Lim, Nur Diana Binte Ishak, Mei Kim Ang, Koji Itahana, Joanne Ngeow, S M Abdullah
Publikováno v:
NPJ Genomic Medicine
Li–Fraumeni syndrome (LFS) is a rare cancer predisposition syndrome usually associated with TP53 germline alterations. Its genetic basis in TP53 wild-type pedigrees is less understood. Using whole-genome sequencing, we identified a germline hemizyg