Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mizue Terai"'
A Prospective Phase II Trial of Radioembolization for Treatment of Uveal Melanoma Hepatic Metastasis
Autor:
Misung Yi, Inna Chervoneva, David J. Eschelman, Takami Sato, P. Rani Anne, Carin F. Gonsalves, Robert D. Adamo, Marlana Orloff, Anthony N. Hage, Mizue Terai
Publikováno v:
Radiology
BACKGROUND: Overall survival (OS) for patients with uveal melanoma (UM) hepatic metastases is extremely poor. Therefore, stabilization of hepatic metastases is essential to prolonging OS. PURPOSE: To assess the safety and effectiveness of radioemboli
Autor:
Lihong Zhang, Mizue Terai, Eduardo F. Farias, Julio A. Aguirre-Ghiso, Clinita E. Randolph, Naiming Zhou, Takami Sato, Timothy J. Purwin, Philip B. Wedegaertner, Andrew E. Aplin, Gregory G. Tall, Shihua Wu, Dougan McGrath, Thomas H. Charpentier, Dominic Lapadula, Jeffrey L. Benovic
Publikováno v:
Molecular Cancer Research. 17:963-973
Uveal melanoma is the most common intraocular tumor in adults and often metastasizes to the liver, leaving patients with few options. Recurrent activating mutations in the G proteins, Gαq and Gα11, are observed in approximately 93% of all uveal mel
Publikováno v:
Cancers
Cancers, Vol 13, Iss 5457, p 5457 (2021)
Cancers, Vol 13, Iss 5457, p 5457 (2021)
Simple Summary Hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (MET) signaling plays an important role in the metastatic formation and therapeutic resistance to uveal melanoma. Here, we review the various functions of MET sign
Autor:
Inna Chervoneva, Jerry A. Shields, Carin F. Gonsalves, Michael J. Mastrangelo, Akira Yamamoto, MaryAnn Laudadio, Carol L. Shields, Takami Sato, David Berd, Kevin L. Sullivan, Mizue Terai, David J. Eschelman, Matias E. Valsecchi
Publikováno v:
Journal of Vascular and Interventional Radiology. 26:523-532.e2
To investigate the effects of immunoembolization with granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with uveal melanoma (UM) with liver-only metastasis.In this double-blind phase II clinical trial, patients were randomized to
Autor:
M. Laudadio, Mizue Terai, Kevin L. Sullivan, Takami Sato, Carin F. Gonsalves, Michael J. Mastrangelo, David J. Eschelman
Publikováno v:
Journal of Clinical Oncology. 29:8577-8577
8577 Background: Immunoembolization of the hepatic artery with GM-CSF (IE) demonstrated potential efficacy in uveal melanoma (UM) patients with hepatic metastasis in a dose-escalating phase I study...
Publikováno v:
Cancer Research. 70:359-359
Uveal melanoma is the most common primary intraocular malignant tumor in adults; 30% to 50% of patients ultimately succumb to metastatic disease, predominantly to hepatic metastasis. Despite new diagnostic and therapeutic tools, the survival rate for