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pro vyhledávání: '"Thomas C. Foster"'
Autor:
Linda A. Bean, Pedro E. Cruz, Asha Rani, Awilda M. Rosario, Thomas C. Foster, Mike Guidi, Todd E. Golde, Ashok Kumar
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(49)
A decline in estradiol (E2)-mediated cognitive benefits denotes a critical window for the therapeutic effects of E2, but the mechanism for closing of the critical window is unknown. We hypothesized that upregulating the expression of estrogen recepto
Publikováno v:
Hormones and Behavior. 34:163-170
This study investigated the role of the estrogen receptor alpha (ERalpha) in mediating performance on a spatial discrimination task, the Morris water maze. Spatial discrimination on this water escape task was examined in eight groups of gonadectomize
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 16(9)
Estrogen, which influences both classical genomic and rapid membrane-associated signaling cascades, has been implicated in the regulation of hippocampal function, including spatial learning. Gene mutation studies suggest that estrogen effects are med