Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Valmik Bhargava"'
Publikováno v:
Neurogastroenterology & Motility. 26:1122-1130
Background Esophageal multiple intraluminal impedance (MII) measurement has been used to detect gastro-esophageal reflux and bolus transport. It is not clear if MII can detect changes in luminal cross sectional area (CSA) during bolus transport. Intr
Publikováno v:
Journal of Neurogastroenterology and Motility
Muscularis propria of the esophagus is organized into circular and longitudinal muscle layers. Goal of this review is to summarize the role of longitudinal muscle in physiology and pathophysiology of esophageal sensory and motor function. Simultaneou
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 303:G529-G535
We recently reported that esophageal contraction reduces esophageal wall perfusion in an animal study. Our aim was to determine esophageal wall blood perfusion (EWBP) during esophageal contraction and transient lower esophageal sphincter relaxations
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G542-G547
A subthreshold pharyngeal stimulus induces lower esophageal sphincter (LES) relaxation and inhibits progression of ongoing peristaltic contraction in the esophagus. Recent studies show that longitudinal muscle contraction of the esophagus may play a
Publikováno v:
Gastroenterology. 140:442-449
Surgical fundoplication is an effective treatment for gastroesophageal reflux disease. One of the proposed mechanisms for its antireflux action is that it reduces lower esophageal sphincter (LES) relaxation. We investigated whether fundoplication wor
Publikováno v:
Gastroenterology. 139:102-111
Background & Aims Achalasia esophagus is characterized by loss of peristalsis and incomplete esophagogastric junction (EGJ) relaxation. We studied mechanisms of esophageal emptying in patients with achalasia using simultaneous high-resolution manomet
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G927-G933
Multipeaked waves (MPW) in the distal esophagus occur frequently in patients with esophageal spastic motor disorders and diabetes mellitus and are thought to represent repetitive esophageal contractions. We aimed to investigate whether the relative m
Mechanism of stretch-activated excitatory and inhibitory responses in the lower esophageal sphincter
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G397-G405
We recently found that an orally directed stretch of the esophagus activates a neurally mediated relaxation of the lower esophageal sphincter (LES). Goals of our study were to characterize the neural mechanisms responsible for axial and transverse st
Autor:
Ranjan Dohil, Alissa McClure Quin, Ravinder K. Mittal, Valmik Bhargava, Hariprasad R. Korsapati, Arash Babaei
Publikováno v:
Gut. 58:1056-1062
Background: Esophageal motility, as measured by manometry, is normal in the majority of patients with eosinophilic esophagitis (EoE). However, manometry measures only the circular muscle function of esophagus. The goal of our study was to assess circ
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 292:G329-G334
Axial stretch: a novel mechanism of the lower esophageal sphincter relaxation. Am J Physiol Gastrointest Liver Physiol 292: G329-G334, 2007. First published October 5, 2006; doi:10.1152/ajpgi.00351.2006.-Swallow and esophageal distension-induced rela