Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Amanda B. Muir"'
Publikováno v:
Pediatric clinics of North America. 68(6)
Eosinophilic esophagitis is an immune-mediated allergic disease of the esophagus that affects pediatric patients of all ages. The diagnosis is made by esophagogastroduodenoscopy demonstrating eosinophilic infiltrate of the esophagus. Approaches to tr
Publikováno v:
Clinical and Experimental Gastroenterology. 12:391-399
Eosinophilic esophagitis (EoE) is a disorder which affects all ages, from infancy through adulthood. It typically affects atopic individuals (Table 1) and is a chronic allergic disorder, with foods ubiquitous in the diet being the most described trig
Autor:
Gary W. Falk, Amanda B. Muir
Publikováno v:
JAMA
IMPORTANCE: Eosinophilic esophagitis (EoE) is a chronic immune mediated inflammatory disease of the esophagus, that affects an estimated approximately 150,000 people in the United States. EoE affects both children and adults and causes dysphagia, foo
Autor:
Amanda B. Muir, Jozef Madzo, Karami A, Hugh H. Huang, Kelsey Keith, Kathryn E. Hamilton, Murray Mg, Klochkova A, Mu A, Marie Pier Tetreault, Tatiana A. Karakasheva, Kelly A. Whelan, Jaroslav Jelinek, Kabir Mf, Saxena R, Cruz-Acuna R
Stratified squamous epithelium of the esophagus is comprised of basal keratinocytes that execute a terminal differentiation program in overlying suprabasal and superficial cell layers. Although morphologic progression coupled with expression of speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466a58736079a723cc38ac10bcd95315
https://doi.org/10.1101/2021.02.08.430312
https://doi.org/10.1101/2021.02.08.430312
Autor:
Mohammad Faujul Kabir, Adam L. Karami, Ricardo Cruz-Acuña, Alena Klochkova, Reshu Saxena, Anbin Mu, Mary Grace Murray, Jasmine Cruz, Annie D. Fuller, Margarette H. Clevenger, Kumaraswamy Naidu Chitrala, Yinfei Tan, Kelsey Keith, Jozef Madzo, Hugh Huang, Jaroslav Jelinek, Tatiana Karakasheva, Kathryn E. Hamilton, Amanda B. Muir, Marie-Pier Tétreault, Kelly A. Whelan
Publikováno v:
Nature communications. 13(1)
Although morphologic progression coupled with expression of specific molecular markers has been characterized along the esophageal squamous differentiation gradient, the molecular heterogeneity within cell types along this trajectory has yet to be cl
Autor:
Bailey Aaron, Masataka Shimonosono, Dominique Bailey, Takeo Hara, Julian A. Abrams, Kathryn E. Hamilton, Yuta Kasagi, Veronique Giroux, Hiroshi Nakagawa, Jonathan M. Spergel, Gary W. Falk, Amanda B. Muir, Tatiana A. Karakasheva, Seema S. Aceves, Kelly A. Whelan, Takashi Kijima, Benjamin J. Wilkins
Publikováno v:
Curr Protoc Stem Cell Biol
The homeostatic proliferation-differentiation gradient in the esophageal epithelium is perturbed under inflammatory disease conditions such as gastroesophageal reflux disease and eosinophilic esophagitis. Herein we describe the protocols for rapid ge
Autor:
Kelly A. Whelan, Benjamin J. Wilkins, Okan U. Elci, Evan S. Dellon, Gary W. Falk, Jonathan Gross, Bridget Godwin, Andres J. Klein-Szanto, Hiroshi Nakagawa, Jonathan M. Spergel, Maureen DeMarshall, Amanda B. Muir, Medha Sharma, Alain Benitez, Chris A. Liacouras
Publikováno v:
Clin Gastroenterol Hepatol
Background & Aims Although eosinophil count is the standard used to monitor disease activity in patients with eosinophilic esophagitis (EoE), there are often disparities between patient-reported symptoms and eosinophil counts. We examined the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9caf01105763de1fa0d9d57e16578429
https://europepmc.org/articles/PMC7058491/
https://europepmc.org/articles/PMC7058491/
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 461-478 (2018)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The stratified squamous epithelium of the esophagus shows a proliferative basal layer of keratinocytes that undergo terminal differentiation in overlying suprabasal layers. Esophageal pathologies, including eosinophilic esophagitis, gastroesophageal
Autor:
Amanda B, Muir
Publikováno v:
Current Problems in Pediatric and Adolescent Health Care. 48:99-101
Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease of the esophagus that effects children and adults. Typical symptoms of EoE typically involve failure to thrive and vomiting in small children, and dysphagia and food impaction
Autor:
Dorottya Laczkó, Divya Rao, Khvaramze Shaverdashvili, Kelly A. Whelan, Amanda B. Muir, Daniel Weinblatt, Wenpeng Jiang, Jennie Padlo, Jonathan P. Katz, Yang Jia, John P. Lynch
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215746 (2019)
Understanding the regulatory mechanisms within esophageal epithelia is essential to gain insight into the pathogenesis of esophageal diseases, which are among the leading causes of morbidity and mortality throughout the world. The zinc-finger transcr