Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michael A. Portelli"'
Publikováno v:
Frontiers in Allergy, Vol 2 (2021)
Asthma affects more than 300 million people globally and is both under diagnosed and under treated. The most recent and largest genome-wide association study investigating moderate to severe asthma to date was carried out in 2019 and identified 25 in
Externí odkaz:
https://doaj.org/article/a8b1f2f2ce564bd298a06dd51d171aed
Autor:
David O. Bates, Vincent Pang, Judith M. Vonk, Charlote K. Billington, John W. Holloway, Sangita Bhaker, Cornelis J. Vermeulen, Don D. Sin, Ian Sayers, Martin D. Tobin, Peter H. Howarth, F. Nicole Dijk, David C. Nickle, Ian P. Hall, Yohan Bossé, Louise V. Wain, Dominick E. Shaw, John D Blakey, Andrew M. Fogarty, Amisha Singapuri, Michael A. Portelli, Martijn C. Nawijn, Cheng J. Xu, Andrew V. Benest, Ma'en Obeidat, Liam G Heaney, Jenny Hankinson, Maarten van den Berge, Rekha Chaudhuri, Angela Simpson, Tricia M. McKeever, Simon R. Johnson, Adel H. Mansur, Robert Niven, Zara Pogson, Gabrielle A. Lockett, Christopher E. Brightling, Amanda P. Henry, Neil C. Thomson, Nick Shrine, Gerard H. Koppelman, Maria Ketelaar, Alen Faiz
Publikováno v:
Journal of Allergy and Clinical Immunology, 147(1), 144-157. MOSBY-ELSEVIER
Background: Asthma is a complex disease with multiple phenotypes that may differ in disease pathobiology and treatment response. IL33 single nucleotide polymorphisms (SNPs) have been reproducibly associated with asthma. IL33 levels are elevated in sp