Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hariharan Easwaran"'
Autor:
Ken Kang Hsin Wang, Zhihao Lu, John Wrangle, Charles M. Rudin, Michelle Vaz, Michael J. Topper, Yuping Mei, Stephen R. Broderick, Drew M. Pardoll, Ray Whay Chiu Yen, Hariharan Easwaran, Rosalyn A. Juergens, Stephen M. Cattaneo, Cynthia A. Zahnow, Joseph B. Margolick, Beverly Lee, Hao Zhang, Yi Cai, Richard J. Battafarano, Yujiao Wang, Kristen Rodgers, Barry D. Nelkin, Patrick M. Forde, Wenbing Xie, Ki Bem Kim, Malcolm V. Brock, Xi Jiao, Jianling Zou, Shuang Li, Yong Tao, Stephen B. Baylin, Stephen C. Yang, Chi-Ping Day, Joanne Riemer, Lin Shen, Errol L. Bush, Yanni Wang, Ying Cui, Huili Li, Young J. Kim, Alicia Hulbert, Peng Huang, Franck Housseau, Weiqiang Zhang, Limin Xia, Bin Zhang, Julie R. Brahmer, Xiangqian Kong
Publikováno v:
Nature. 579:284-290
Cancer recurrence after surgery remains an unresolved clinical problem1–3. Myeloid cells derived from bone marrow contribute to the formation of the premetastatic microenvironment, which is required for disseminating tumour cells to engraft distant
Autor:
Dylan Conklin, Victor E. Velculescu, Doreen N. Palsgrove, Daniel C. Bruhm, Gottfried E. Konecny, Michaël Noë, Hariharan Easwaran, Michael F. Press, Ioannis Kagiampakis, Yasuto Kinose, Dorothy Hallberg, James R. White, Ronny Drapkin, Eniko Papp, Stephen B. Baylin, Dennis J. Slamon, Robert B. Scharpf, Vilmos Adleff
Publikováno v:
Cell reports
SUMMARY To improve our understanding of ovarian cancer, we performed genome-wide analyses of 45 ovarian cancer cell lines. Given the challenges of genomic analyses of tumors without matched normal samples, we developed approaches for detection of som
Autor:
Steve Baylin, Hariharan Easwaran, Vinod Krishna, Kurtis E. Bachman, Sehej Parmar, Yuba R. Bhandari, Rachael Powers
Publikováno v:
Cancer Research. 81:2107-2107
Colorectal cancer (CRC) is classified into distinct subtypes based on genetic, epigenetic and/or transcriptional subtypes. The underlying mechanisms that drive these subtypes are unknown. By integrating whole genome DNA methylation, gene expression,
Autor:
Nilofer S. Azad, Stephen B. Baylin, Joel Picus, Charles Erlichman, Ross C. Donehower, Ann L. Oberg, Peter W. Laird, Patrick J. Flynn, Prakriti Medvari, Hariharan Easwaran, Anthony B. El-Khoueiry, Nathan Bahary, Ihab R. Kamel, Thomas M. Brown, Daniel J. Weisenberger, Jun Yin, Peter A. Jones, Hui Shen, Anup Sharma, Henry C. Pitot, George P. Kim, Nita Ahuja, Douglas Adkins, Richard Piekarz
Publikováno v:
Oncotarget
// Nilofer S. Azad 1 , Anthony el-Khoueiry 2 , Jun Yin 3 , Ann L. Oberg 3 , Patrick Flynn 4 , Douglas Adkins 5 , Anup Sharma 1 , Daniel J. Weisenberger 2 , Thomas Brown 1 , Prakriti Medvari 1 , Peter A. Jones 6 , Hariharan Easwaran 1 , Ihab Kamel 1 ,
Autor:
Miguel A. Peinado, Xiangqian Kong, Shinji Maegawa, Nicholas C. Zachos, Yong Tao, Yuba R. Bhandari, Byunghak Kang, Elana J. Fertig, Jean Pierre J. Issa, Yi Cai, Wenbing Xie, Stephen B. Baylin, Daniel A. Petkovich, Izaskun Mallona, Genevieve Stein-O’Brien, Ray Whay Chiu Yen, Yuezheng Zhang, Hariharan Easwaran, Nita Ahuja, Stephen M. Brown, Cynthia A. Zahnow, Xiaojian Shao, Jai Thakor, Himani Vaidya, Zhihao Lu, Julie In
Publikováno v:
Cancer Cell
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
We addressed the precursor role of aging-like spontaneous promoter DNA hypermethylation in initiating tumorigenesis. Using mouse colon-derived organoids, we show that promoter hypermethylation spontaneously arises in cells mimicking the human aging-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726d795dd960279d63396d9c2016bc01
https://europepmc.org/articles/PMC6636642/
https://europepmc.org/articles/PMC6636642/
Autor:
Hariharan Easwaran, Stephen B. Baylin
Publikováno v:
RNA Technologies ISBN: 9783030147914
DNA methylation is a key epigenetic mark in the heritable regulation of gene expression, with important roles in normal development and disease. Genomewide alterations in DNA methylation patterns are universal feature across cancers. Studies in the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d02ffe5617a20f976c86d6b371e80c2
https://doi.org/10.1007/978-3-030-14792-1_2
https://doi.org/10.1007/978-3-030-14792-1_2
Publikováno v:
Oncoscience
Publikováno v:
Cancer Research. 80:A36-A36
Background: Tumor initiation and development occur not necessarily by genetic changes alone, but in the context of the epigenome and cell microenvironment. Growing evidence indicate that cancer risk factors, such as aging and inflammation, may primar
Autor:
Fabian M. Johnston, Yen-Yi Juo, Nita Ahuja, Emmanouil P. Pappou, M. van Engeland, Tsung Yu, Hariharan Easwaran, Han Wang, Steve Baylin, H. H. Juo, Dongyu Zhang
Publikováno v:
Annals of Oncology, 25(12), 2314-2327. Oxford University Press
Background Divergent findings regarding the prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) patients exist in current literature. We aim to review data from published studies in order to examine the association b
Autor:
Jiang Qian, Dylan Z. Kelley, Daria A. Gaykalova, Alexander V. Favorov, Emily Flam, Heather C. Wick, Luciane T. Kagohara, Elana J. Fertig, Hariharan Easwaran, Genevieve Stein-O’Brien, Ludmila Danilova
Publikováno v:
Briefings in Functional Genomics
Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in even individual malignant cells. Epigenetic changes are critical mediators of these functional changes that drive and maintain the malignant phenotype. Changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d0b13ef7dbd8bde9336bce36fde098