Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hariharan Easwaran"'
Autor:
Fabian M. Johnston, Yen-Yi Juo, Nita Ahuja, Emmanouil P. Pappou, M. van Engeland, Tsung Yu, Hariharan Easwaran, Han Wang, Steve Baylin, H. H. Juo, Dongyu Zhang
Publikováno v:
Annals of Oncology, 25(12), 2314-2327. Oxford University Press
Background Divergent findings regarding the prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) patients exist in current literature. We aim to review data from published studies in order to examine the association b
Autor:
Jiang Qian, Dylan Z. Kelley, Daria A. Gaykalova, Alexander V. Favorov, Emily Flam, Heather C. Wick, Luciane T. Kagohara, Elana J. Fertig, Hariharan Easwaran, Genevieve Stein-O’Brien, Ludmila Danilova
Publikováno v:
Briefings in Functional Genomics
Cancer is a complex disease, driven by aberrant activity in numerous signaling pathways in even individual malignant cells. Epigenetic changes are critical mediators of these functional changes that drive and maintain the malignant phenotype. Changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d0b13ef7dbd8bde9336bce36fde098
Publikováno v:
Molecular Cell. 54:716-727
The existence of subpopulations of cells in cancers with increased tumor-initiating capacities and self-renewal potential, often termed "cancer stem cells," is a much discussed and key area of cancer biology. Such cellular heterogeneity is very impor
Autor:
Roisin M. Connolly, Angela A. Guzzetta, Stephen B. Baylin, Vered Stearns, Nancy E. Davidson, Cynthia A. Zahnow, Dennis J. Slamon, Nilofer S. Azad, Rajita Vatapalli, Huili Li, Jianjun Luo, Nita Ahuja, Katherine B. Chiappinelli, Michael J. Topper, Peter A. Jones, Drew M. Pardoll, Ray Whay Chiu Yen, Hariharan Easwaran
Publikováno v:
Oncotarget
// Huili Li 1,* , Katherine B. Chiappinelli 1,* , Angela A. Guzzetta 1,* , Hariharan Easwaran 1 , Ray-Whay Chiu Yen 1 , Rajita Vatapalli 1 , Michael J. Topper 1 , Jianjun Luo 1 , Roisin M. Connolly 1,2 , Nilofer S. Azad 1 , Vered Stearns 1,2 , Drew M
Autor:
Helai P. Mohammad, Heather M. O'Hagan, Stephen B. Baylin, Joyce E. Ohm, Yi Cai, Hariharan Easwaran, Leander Van Neste, Kelly M. McGarvey
Publikováno v:
Cancer Research. 69:6322-6330
Epigenetic silencing of genes in association with aberrant promoter DNA hypermethylation has emerged as a significant mechanism in the development of human cancers. Such genes are also often targets of the polycomb group repressive complexes in embry
Epigenetic therapies may play a prominent role in the future management of solid tumors. This possibility is based on the clinical efficacy of existing drugs in treating defined hematopoietic neoplasms, paired with promising new data from preclinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ffff45104be949a1387b6ef8aaa565
https://europepmc.org/articles/PMC3871229/
https://europepmc.org/articles/PMC3871229/