Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nico Lakenberg"'
Autor:
Rodrigo Coutinho de Almeida, Margo Tuerlings, Marcella van Hoolwerff, H. Eka D. Suchiman, Ingrid Meulenbelt, Davy Cats, Hailiang Mei, Demien Broekhuis, Rob G H H Nelissen, Yolande F M Ramos, Nico Lakenberg, Paula P.I. Metselaar
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis and Rheumatology, 72(11), 1845-1854. WILEY
Arthritis and Rheumatology, 72(11), 1845-1854. WILEY
OBJECTIVE To identify robustly differentially expressed long noncoding RNAs (lncRNAs) with osteoarthritis (OA) pathophysiology in cartilage and to explore potential target messenger RNA (mRNA) by establishing coexpression networks, followed by functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19b73b4d8a3d9c920a440ee513e4f85
https://hdl.handle.net/1887/3182204
https://hdl.handle.net/1887/3182204
Autor:
Jenny van Dongen, Nuno R. Zilhão, Karen Sugden, Eilis J. Hannon, Jonathan Mill, Avshalom Caspi, Jessica Agnew-Blais, Louise Arseneault, David L. Corcoran, Terrie E. Moffitt, Richie Poulton, Barbara Franke, Dorret I. Boomsma, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce van Meurs, Aaron Isaacs, Rick Jansen, Lude Franke, René Pool, Jouke J. Hottenga, Marleen M.J. van Greevenbroek, Coen D.A. Stehouwer, Carla J.H. van der Kallen, Casper G. Schalkwijk, Cisca Wijmenga, Sasha Zhernakova, Ettje F. Tigchelaar, P. Eline Slagboom, Marian Beekman, Joris Deelen, Diana van Heemst, Jan H. Veldink, Leonard H. van den Berg, Cornelia M. van Duijn, Bert A. Hofman, André G. Uitterlinden, P. Mila Jhamai, Michael Verbiest, H. Eka D. Suchiman, Marijn Verkerk, Ruud van der Breggen, Jeroen van Rooij, Nico Lakenberg, Hailiang Mei, Maarten van Iterson, Michiel van Galen, Jan Bot, Dasha V. Zhernakova, Peter van ’t Hof, Patrick Deelen, Irene Nooren, Matthijs Moed, Martijn Vermaat, René Luijk, Marc Jan Bonder, Freerk van Dijk, Wibowo Arindrarto, Szymon M. Kielbasa, Morris A. Swertz, Erik. W. van Zwet, Peter-Bram ’t Hoen
Publikováno v:
Biological Psychiatry, 86(8), 599-607. Elsevier Inc.
Biological Psychiatry, 86(8), 599-607. ELSEVIER SCIENCE INC
Biological Psychiatry, 86(8), 599-607
Biological Psychiatry, 86(8), 599-607. Elsevier Science
Biological Psychiatry, 86(8), 599-607. Elsevier USA
van Dongen, J, Zilhão, N R, Sugden, K, Heijmans, B T, ’t Hoen, P A C, van Meurs, J, Isaacs, A, Jansen, R, Franke, L, Boomsma, D I, Pool, R, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Slagboom, P E, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Iterson, M, van Galen, M, Bot, J, Zhernakova, D V, Hof, P V, Deelen, P, Nooren, I, Matthijs, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, BIOS Consortium, Kielbasa, S M, Swertz, M A, van Zwet, E W, ’t Hoen, P-B, Hannon, E, Mill, J, Caspi, A, Arseneault, L, Corcoran, D L, Moffitt, TE, Poulton, R, Franke, B & Boomsma, D I 2019, ' Epigenome-wide association study of Attention-Deficit/Hyperactivity Disorder symptoms in adults ', Biological Psychiatry, vol. 86, no. 8, pp. 599-607 . https://doi.org/10.1016/j.biopsych.2019.02.016
Biological Psychiatry, 86, 599-607
Biological Psychiatry, 86, 8, pp. 599-607
van Dongen, J, Zilhão, N R, Sugden, K, Hannon, E J, Mill, J, Caspi, A, Agnew-Blais, J, Arseneault, L, Corcoran, D L, Moffitt, T E, Poulton, R, Franke, B, Boomsma, D I & BIOS Consortium 2019, ' Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults ', Biological Psychiatry, vol. 86, no. 8, pp. 599-607 . https://doi.org/10.1016/j.biopsych.2019.02.016
Biological Psychiatry, 86(8), 599-607. ELSEVIER SCIENCE INC
Biological Psychiatry, 86(8), 599-607
Biological Psychiatry, 86(8), 599-607. Elsevier Science
Biological Psychiatry, 86(8), 599-607. Elsevier USA
van Dongen, J, Zilhão, N R, Sugden, K, Heijmans, B T, ’t Hoen, P A C, van Meurs, J, Isaacs, A, Jansen, R, Franke, L, Boomsma, D I, Pool, R, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Slagboom, P E, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Iterson, M, van Galen, M, Bot, J, Zhernakova, D V, Hof, P V, Deelen, P, Nooren, I, Matthijs, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, BIOS Consortium, Kielbasa, S M, Swertz, M A, van Zwet, E W, ’t Hoen, P-B, Hannon, E, Mill, J, Caspi, A, Arseneault, L, Corcoran, D L, Moffitt, TE, Poulton, R, Franke, B & Boomsma, D I 2019, ' Epigenome-wide association study of Attention-Deficit/Hyperactivity Disorder symptoms in adults ', Biological Psychiatry, vol. 86, no. 8, pp. 599-607 . https://doi.org/10.1016/j.biopsych.2019.02.016
Biological Psychiatry, 86, 599-607
Biological Psychiatry, 86, 8, pp. 599-607
van Dongen, J, Zilhão, N R, Sugden, K, Hannon, E J, Mill, J, Caspi, A, Agnew-Blais, J, Arseneault, L, Corcoran, D L, Moffitt, T E, Poulton, R, Franke, B, Boomsma, D I & BIOS Consortium 2019, ' Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults ', Biological Psychiatry, vol. 86, no. 8, pp. 599-607 . https://doi.org/10.1016/j.biopsych.2019.02.016
Contains fulltext : 209008.pdf (Publisher’s version ) (Open Access) BACKGROUND: Previous studies have reported associations between attention-deficit/hyperactivity disorder symptoms and DNA methylation in children. We report the first epigenome-wid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11873a019ce25df0fa87e8d37a996e29
https://pure.eur.nl/en/publications/67b92a1a-561a-42ea-8fae-6f9d8cb68e2c
https://pure.eur.nl/en/publications/67b92a1a-561a-42ea-8fae-6f9d8cb68e2c
Autor:
Marleen M.J. van Greevenbroek, Erik W. van Zwet, Jeroen van Rooij, Wibowo Arindrarto, Tianxiao Huan, Marijn Verkerk, Allan C. Just, Cisca Wijmenga, Coen D.A. Stehouwer, Cornelia M. van Duijn, Coleen M. Damcott, Symen Ligthart, Dorret I. Boomsma, Cristina Menni, Hailiang Mei, Guosheng Zhang, Eric Boerwinkle, Diana van Heemst, Albert Hofman, Casper G. Schalkwijk, Jordana T. Bell, Carla J.H. van der Kallen, John M. Starr, Yucheng Jia, Andrea A. Baccarelli, Jeffrey R. O'Connell, Joyce B. C van Meurs, Steve Horvath, Allan F. McRae, Leonard H. van den Berg, Walter Palmas, Szymon M. Kielbasa, Freerk van Dijk, Stephen Turner, Sharon L.R. Kardia, Donna K. Arnett, Devin Absher, James D. Stewart, Jerome I. Rotter, Jouke J. Hottenga, Rahul Gondalia, Jan Bot, Joris Deelen, René Pool, Tomáš Paus, Yii-Der Ida Chen, Peter A.C. ’t Hoen, Thomas H. Mosley, René Luijk, Zdenka Pausova, Ettje F. Tigchelaar, Bastiaan T. Heijmans, André G. Uitterlinden, P. Mila Jhamai, Eric A. Whitsel, Alanna C. Morrison, Patrick Deelen, Lude Franke, Riccardo E. Marioni, Chunyu Liu, Rick Jansen, Marc Jan Bonder, J. H. Veldink, Xiuqing Guo, Oscar H. Franco, Yongmei Liu, Nona Sotoodehnia, Nico Lakenberg, Joel Schwartz, Daniel Levy, Catriona Syme, May E. Montasser, Irene Nooren, Elias Salfati, Michael M. Mendelson, Abbas Dehghan, Tim D. Spector, Jan Bressler, Jennifer A. Smith, Matthijs Moed, H. Eka D. Suchiman, Martijn Vermaat, Alan R. Shuldiner, Michael M. P. J. Verbiest, A Isaacs, Dasha V. Zhernakova, Jennifer A. Brody, Alexandra Zhernakova, Wei Zhao, Marian Beekman, Ian J. Deary, Maarten van Iterson, Min A. Jhun, Michiel van Galen, Weihua Guan, Jincheng Shen, Stella Aslibekyan, Myriam Fornage, Joyce B. J. van Meurs, Pantel S. Vokonas, Bruce M. Psaty, Melissa A. Richard, Peter Van ‘t Hof, Yun Li, Morris A. Swertz, Themistocles L. Assimes, P. Eline Slagboom, Jenny van Dongen, Pei-Chien Tsai, Lifang Hou, Ruud van der Breggen, Marguerite R. Irvin, Joshua C. Bis
Publikováno v:
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, BIOS Consortium, Boomsma, D I, Pool, R, van Dongen, J & Hottenga, J J 2017, ' DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
American Journal of Human Genetics, 101(6), 888-902. Cell Press
American journal of human genetics, vol 101, iss 6
American Journal of Human Genetics, 101(6), 888-902
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, Palmas, W, Liu, Y & Smith, J A & Deary, I J 2017, ' DNA methylation analysis identifies loci for blood pressure regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
American Journal of Human Genetics, 101(6), 888-902. Cell Press
American journal of human genetics, vol 101, iss 6
American Journal of Human Genetics, 101(6), 888-902
Richard, M A, Huan, T, Ligthart, S, Gondalia, R, Jhun, M A, Brody, J A, Irvin, M R, Marioni, R, Shen, J, Tsai, P-C, Montasser, M E, Jia, Y, Syme, C, Salfati, E L, Boerwinkle, E, Guan, W, Mosley, T H, Bressler, J, Morrison, A C, Liu, C, Mendelson, M M, Uitterlinden, A G, van Meurs, J B, Franco, O H, Zhang, G, Li, Y, Stewart, J D, Bis, J C, Psaty, B M, Chen, Y-D I, Kardia, S L R, Zhao, W, Turner, S T, Absher, D, Aslibekyan, S, Starr, J M, McRae, A F, Hou, L, Just, A C, Schwartz, J D, Vokonas, P S, Menni, C, Spector, T D, Shuldiner, A, Damcott, C M, Rotter, J I, Palmas, W, Liu, Y & Smith, J A & Deary, I J 2017, ' DNA methylation analysis identifies loci for blood pressure regulation ', American Journal of Human Genetics, vol. 101, no. 6, pp. 888-902 . https://doi.org/10.1016/j.ajhg.2017.09.028
Genome-wide association studies have identified hundreds of genetic variants associated with blood pressure (BP), but sequence variation accounts for a small fraction of the phenotypic variance. Epigenetic changes may alter the expression of genes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f9a42b3b8c7e77be3a72983127a651
https://hdl.handle.net/1871.1/51b0b3db-be77-422d-8855-2ee913d5b802
https://hdl.handle.net/1871.1/51b0b3db-be77-422d-8855-2ee913d5b802
Autor:
Peter Van ‘t Hof, Erik W. van Zwet, Matthijs Moed, Jeroen van Rooij, Joris Deelen, Freerk van Dijk, Nico Lakenberg, Cisca Wijmenga, André G. Uitterlinden, Rick Jansen, Maarten van Iterson, Dasha V. Zhernakova, Szymon M. Kielbasa, Martijn Vermaat, Marleen J. van Greevenbroek, Hailiang Mei, Cornelia M. van Duijn, René Pool, Jan Bot, Lude Franke, Sasha Zhernakova, Michiel van Galen, H. Eka D. Suchiman, Morris A. Swertz, Marc Jan Bonder, Bert A. Hofman, Wibowo Arindrarto, Joyce B. J. van Meurs, Jouke J. Hottenga, Coen D.A. Stehouwer, Jenny van Dongen, Michael M. P. J. Verbiest, René Luijk, P. Eline Slagboom, Patrick Deelen, Dorret I. Boomsma, Jan H. Veldink, Leonard H. van den Berg, Diana van Heemst, Aaron Isaacs, Marijn Verkerk, Peter A C 't Hoen, Ruud van der Breggen, Casper G. Schalkwijk, Ettje F. Tigchelaar, Peter Bram 't Hoen, Marian Beekman, Carla J.H. van der Kallen, Bastiaan T. Heijmans, P. Mila Jhamai, Irene Nooren
Publikováno v:
Genome Biology, 18(1):19. Springer Verlag
Genome Biology, 18(1):19. BioMed Central Ltd.
van Iterson, M, van Zwet, E W, Heijmans, B T, ’t Hoen, P A C, van Meurs, J B J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Van Greevenbroek, M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology, 18
van Iterson, M, van Zwet, E W, Heijmans, B T, 't Hoen, P A C, van Meurs, J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology
Genome Biology, 18(1):19. BioMed Central Ltd.
van Iterson, M, van Zwet, E W, Heijmans, B T, ’t Hoen, P A C, van Meurs, J B J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, Van Greevenbroek, M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology, 18
van Iterson, M, van Zwet, E W, Heijmans, B T, 't Hoen, P A C, van Meurs, J, Jansen, R, Franke, L, Boomsma, D I, Pool, R, van Dongen, J, Hottenga, J J, van Greevenbroek, M M J, Stehouwer, C D A, van der Kallen, C J H, Schalkwijk, C G, Wijmenga, C, Zhernakova, S, Tigchelaar, E F, Eline Slagboom, P, Beekman, M, Deelen, J, van Heemst, D, Veldink, J H, van den Berg, L H, van Duijn, C M, Hofman, B A, Isaacs, A, Uitterlinden, A G, Jhamai, P M, Verbiest, M, Suchiman, H E D, Verkerk, M, van der Breggen, R, van Rooij, J, Lakenberg, N, Mei, H, van Galen, M, Bot, J, Zhernakova, D V, van 't Hof, P, Deelen, P, Nooren, I, Moed, M, Vermaat, M, Luijk, R, Bonder, M J, van Dijk, F, Arindrarto, W, Kielbasa, S M, Swertz, M A & 't Hoen, P B 2017, ' Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution ', Genome Biology, vol. 18, no. 1, 19 . https://doi.org/10.1186/s13059-016-1131-9
Genome Biology
We show that epigenome- and transcriptome-wide association studies (EWAS and TWAS) are prone to significant inflation and bias of test statistics, an unrecognized phenomenon introducing spurious findings if left unaddressed. Neither GWAS-based method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c64cec6e93f81a6586330768430c9b
https://hdl.handle.net/1887/114294
https://hdl.handle.net/1887/114294
Autor:
Ruud van der Breggen, Annelies E van Eeden, Nico Lakenberg, Steffan D. Bos, Ingrid Meulenbelt, Nils Bomer, Arash Darvishan, Willeke M. C. van Roon-Mom, Barry A. Pepers, Rob G H H Nelissen, Fons J. Verbeek, Bastiaan T. Heijmans, Yolande F. M. Ramos, P. Eline Slagboom, Elmar W. Tobi, Wouter den Hollander, B.J. Duijnisveld, Gerjo J.V.M. van Osch, Erik B. van den Akker
Publikováno v:
Annals of the Rheumatic Diseases: 74 (8), 2015
Annals of the Rheumatic Diseases, 74(8), 1571-1579. BMJ Publishing Group
Annals of the Rheumatic Diseases, 74(8), 1571-1579
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 74(8), 1571-1579. BMJ Publishing Group
Annals of the Rheumatic Diseases, 74(8), 1571-1579
Annals of the Rheumatic Diseases
Objectives To investigate how the genetic susceptibility gene DIO2 confers risk to osteoarthritis (OA) onset in humans and to explore whether counteracting the deleterious effect could contribute to novel therapeutic approaches. Methods Epigeneticall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c22b9d9968f753cebedfac205d6d725
https://hdl.handle.net/1887/107198
https://hdl.handle.net/1887/107198
Autor:
W. den Hollander, R. van der Breggen, Ingrid Meulenbelt, Steffan D. Bos, Yolande F. M. Ramos, Nico Lakenberg, Nils Bomer, W.J. de Dijcker, Rob G H H Nelissen, P.E. Slagboom, B.J. Duijnisveld
Publikováno v:
Annals of the Rheumatic Diseases, 73(12), 2208-2212
Objectives To elucidate the functional epigenomic landscape of articular cartilage in osteoarthritis (OA) affected knee and hip joints in relation to gene expression. Methods Using Illumina Infinium HumanMethylation450 BeadChip arrays, genome-wide DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defeba55a1aefad4ac4375549f983681
http://hdl.handle.net/1887/102889
http://hdl.handle.net/1887/102889
Autor:
Wouter, den Hollander, Yolande F M, Ramos, Nils, Bomer, Stefan, Elzinga, Ruud, van der Breggen, Nico, Lakenberg, Wesley J, de Dijcker, H Eka D, Suchiman, Bouke J, Duijnisveld, Jeanine J, Houwing-Duistermaat, P Eline, Slagboom, Steffan D, Bos, Rob G H H, Nelissen, Ingrid, Meulenbelt
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 67(8)
To identify osteoarthritis (OA) progression-modulating pathways in articular cartilage and their respective regulatory epigenetic and genetic determinants in end-stage disease.Transcriptional activity of CpG was assessed using gene expression data an