Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Edurne San José-Enériz"'
Autor:
Antonio Garcia-Gomez, Laura San-Segundo, Laura Ciudad, Manel Esteller, Xabier Morales, Esteban Ballestar, Javier Rodríguez-Ubreva, Carlos Ortiz-de-Solorzano, Julen Oyarzabal, Felipe Prosper, Mercedes Garayoa, Tianlu Li, Sandra Muntión, Montserrat Martín-Sánchez, Xabier Agirre, Edurne San José-Enériz, Carlos de la Calle-Fabregat, Gerard Godoy-Tena, Francesc Català-Moll
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digital.CSIC. Repositorio Institucional del CSIC
Universidad de Barcelona
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Digital.CSIC. Repositorio Institucional del CSIC
© The Author(s) 2021.
Multiple myeloma (MM) progression and myeloma-associated bone disease (MBD) are highly dependent on bone marrow mesenchymal stromal cells (MSCs). MM-MSCs exhibit abnormal transcriptomes, suggesting the involvement of epige
Multiple myeloma (MM) progression and myeloma-associated bone disease (MBD) are highly dependent on bone marrow mesenchymal stromal cells (MSCs). MM-MSCs exhibit abnormal transcriptomes, suggesting the involvement of epige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe16b4cd0ce50169152c027ce7ca5a9
http://hdl.handle.net/2445/174307
http://hdl.handle.net/2445/174307
Autor:
Elias Campo, Renée Beekman, Raquel Ordoñez, Cem Meydan, Teresa Ezponda, Stella Charalampopoulou, Guillem Clot, Ari Melnick, Bruno Paiva, Constantine S. Mitsiades, Ruba Y. Taha, Vicente Chapaprieta, Jesus San Miguel, Hendrik G. Stunnenberg, Beatriz García-Torre, Arantxa Carrasco-Leon, Felipe Prosper, Nuria Russiñol, Leire Garate, Halima El-Omri, Edurne San José-Enériz, José I. Martín-Subero, Joost H.A. Martens, Roser Vilarrasa-Blasi, Jonathan D. Licht, Amaia Vilas-Zornoza, Daphné Dupéré-Richer, Marta Kulis, Juan R. Rodriguez-Madoz, Ivo Gut, David Lara-Astiaso, Xabier Agirre, Paula Soler-Vila, Paul Flicek, Rebeca Martínez-Turrilas, Núria Verdaguer-Dot, Estíbaliz Miranda, Martí Duran-Ferrer, Maria J. Calasanz
Publikováno v:
Genome Research, 30, 9, pp. 1217-1227
Genome Res
Genome Research, 30, 1217-1227
Genome Res
Genome Research, 30, 1217-1227
Multiple myeloma (MM) is a plasma cell neoplasm associated with a broad variety of genetic lesions. In spite of this genetic heterogeneity, MMs share a characteristic malignant phenotype whose underlying molecular basis remains poorly characterized.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58806fdc212870e982fcf594422e8812
https://doi.org/10.1101/740027
https://doi.org/10.1101/740027
Autor:
Nicolás, Martínez-Calle, Marien, Pascual, Raquel, Ordoñez, Edurne San José, Enériz, Marta, Kulis, Estíbaliz, Miranda, Elisabeth, Guruceaga, Víctor, Segura, María José, Larráyoz, Beatriz, Bellosillo, María José, Calasanz, Carles, Besses, José, Rifón, José I, Martín-Subero, Xabier, Agirre, Felipe, Prosper
Publikováno v:
Haematologica
In this study we interrogated the DNA methylome of myelofibrosis patients using high-density DNA methylation arrays. We detected 35,215 differentially methylated CpG, corresponding to 10,253 genes, between myelofibrosis patients and healthy controls.
Autor:
José Manuel García-Verdugo, Lidia Agueda, Avik Datta, Ana C. Queirós, Ivo Gut, Marien Pascual, Paul Flicek, Julie Blanc, Giancarlo Castellano, Xabier Agirre, José I. Martín-Subero, Norma C. Gutiérrez, Simon Heath, Anna Esteve, Emanuele Raineri, Michael I. Robson, Reiner Siebert, Elias Campo, Renée Beekman, David S. Richardson, María José Calasanz, Joost H.A. Martens, Eric C. Schirmer, Fang Fang, Jesús F. San Miguel, Marta Gut, Marta Kulis, Anke K. Bergmann, Elisabeth Guruceaga, Nuria Russiñol, Hendrik G. Stunnenberg, Ari Melnick, Laura Clarke, Edurne San José-Enériz, Juan R. Rodriguez-Madoz, Victor Segura, Angelika Merkel, Felipe Prosper
Publikováno v:
Genome Research, 25, 478-487
Genome Research, 25, 4, pp. 478-487
BLOOD
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
ResearcherID
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
GENOME RESEARCH
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona
Agirre, X, Castellano, G, Pascual, M, Heath, S, Kulis, M, Segura, V, Bergmann, A, Esteve, A, Merkel, A, Raineri, E, Agueda, L, Blanc, J, Richardson, D, Clarke, L, Datta, A, Russiñol, N, Queirós, A C, Beekman, R, Rodríguez-Madoz, J R, José-Enériz, E S, Fang, F, Gutiérrez, N C, García-Verdugo, J M, Robson, M I, Schirmer, E C, Guruceaga, E, Martens, J H A, Gut, M, Calasanz, M J, Flicek, P, Siebert, R, Campo, E, San Miguel, J F, Melnick, A, Stunnenberg, H G, Gut, I G, Prosper, F & Martín-Subero, J I 2015, ' Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers ', Genome Research, vol. 25, no. 4, pp. 478-487 . https://doi.org/10.1101/gr.180240.114
Genome Research, 25, 4, pp. 478-487
BLOOD
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
instname
ResearcherID
r-CIPF: Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Centro de Investigación Principe Felipe (CIPF)
GENOME RESEARCH
Recercat. Dipósit de la Recerca de Catalunya
Dipòsit Digital de la UB
Universidad de Barcelona
Agirre, X, Castellano, G, Pascual, M, Heath, S, Kulis, M, Segura, V, Bergmann, A, Esteve, A, Merkel, A, Raineri, E, Agueda, L, Blanc, J, Richardson, D, Clarke, L, Datta, A, Russiñol, N, Queirós, A C, Beekman, R, Rodríguez-Madoz, J R, José-Enériz, E S, Fang, F, Gutiérrez, N C, García-Verdugo, J M, Robson, M I, Schirmer, E C, Guruceaga, E, Martens, J H A, Gut, M, Calasanz, M J, Flicek, P, Siebert, R, Campo, E, San Miguel, J F, Melnick, A, Stunnenberg, H G, Gut, I G, Prosper, F & Martín-Subero, J I 2015, ' Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers ', Genome Research, vol. 25, no. 4, pp. 478-487 . https://doi.org/10.1101/gr.180240.114
Analyzing the DNA methylome of multiple myeloma (MM), a plasma cell neoplasm, by whole-genome bisulfite sequencing and high-density arrays, we observed regional DNA hypermethylation embedded in extensive global hypomethylation. In contrast to the wid
Autor:
Jose A. Martinez-Climent, Giancarlo Castellano, Xabier Agirre, María José García-Barchino, Estíbaliz Miranda, Victor Segura, Ander Estella-Hermoso de Mendoza, Edurne San José-Enériz, Matías A. Avila, Ramón Campos-Olivas, Clara M. Santiveri, José I. Martín-Subero, Juan A. Sánchez-Arias, Rosa María Alvarez, Juan José Lasarte, Juan R. Rodriguez-Madoz, Ana Ugarte, François-Xavier Ogi, Obdulia Rabal, Bruno Paiva, Sergio Roa, Maite Garcia Fernandez de Barrena, Felipe Prosper, Julen Oyarzabal, Amaia Vilas-Zornoza, Pierre Soule, Noelia Casares
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Repisalud
Instituto de Salud Carlos III (ISCIII)
The indisputable role of epigenetics in cancer and the fact that epigenetic alterations can be reversed have favoured development of epigenetic drugs. In this study, we design and synthesize potent novel, selective and reversible chemical probes that
Publikováno v:
Epigenomics. 5:525-538
Acute lymphoblastic leukemia (ALL) is a heterogeneous cancer that is characterized by rapid and uncontrolled proliferation of immature B- or T-lymphoid precursors. Although ALL has been regarded as a genetic disease for many years, the crucial import
Autor:
Felipe Prosper, Francisco Cervantes, Jose A. Martinez-Climent, Vicente Fresquet, Antonio Torres, Xabier Agirre, Victor Arqueros, Jose Roman-Gomez, Edurne San José-Enériz, Vanesa Martin, Leire Garate, Antonio Jiménez-Velasco, Lucia Cordeu, Anabel Heiniger
Publikováno v:
European Journal of Cancer. 45:1877-1889
Background Expression of the pro-apoptotic BCL-2-interacting mediator ( BIM ) has recently been implicated in imatinib-induced apoptosis of BCR-ABL1 + cells. However, the mechanisms involved in the regulation of BIM in CML and its role in the clinica
Autor:
Felipe Prosper, Juan A. Castillejo, Francisco Cervantes, Lucia Cordeu, Jose Roman-Gomez, German Navarro, Leire Garate, Anabel Heiniger, Xabier Agirre, Antonio Jiménez-Velasco, Edurne San José-Enériz, Antoni Torres
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
instname
instname
Journal Article; BACKGROUND AND OBJECTIVES Cancer testis antigens (CTA) provide attractive targets for cancer-specific immunotherapy. Although CTA genes are expressed in some normal tissues, such as the testis, this immunologically protected site lac
Autor:
Miguel A. Sanz, José Cervera, Edurne San José-Enériz, Antoni Torres, Jose Roman-Gomez, Paula Rodriguez-Otero, Vanesa Martín, Amaia Vilas-Zornoza, Xabier Agirre, Concepción Herrera, Felipe Prosper, Ana Valencia
Wnt5a is a member of the Wnt family of proteins that signals through the non-canonical Wnt ⁄ Ca2+pathway to suppress cyclin D1. Deregulation of this pathway has been found in animal models suggesting that it acts as tumour suppressor in acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04337c6a8672348df0fa11a2d4661041
https://hdl.handle.net/10171/18158
https://hdl.handle.net/10171/18158
Autor:
Amaia Vilas-Zornoza, Anabel Heiniger, José Rifón, Paula Rodriguez-Otero, Leire Garate, Felipe Prosper, Xabier Agirre, Vanesa Martín, Jose Roman-Gomez, Eva Bandrés, Edurne San José-Enériz, Lucia Cordeu, Antoni Torres, Antonio Jiménez-Velasco, Puri Fortes, Reiner Siebert, María José Calasanz, Gloria Abizanda, José I. Martín-Subero
Publikováno v:
Cancer research. 69(10)
Whereas transcriptional silencing of genes due to epigenetic mechanisms is one of the most important alterations in acute lymphoblastic leukemia (ALL), some recent studies indicate that DNA methylation contributes to down-regulation of miRNAs during