Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Ralph B. D'Agostino"'
Autor:
Annika Hoyer, Ralph Brinks, Thaddäus Tönnies, Sharon H. Saydah, Ralph B. D’Agostino, Jasmin Divers, Scott Isom, Dana Dabelea, Jean M. Lawrence, Elizabeth J. Mayer-Davis, Catherine Pihoker, Lawrence Dolan, Giuseppina Imperatore
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Incidence is one of the most important epidemiologic indices in surveillance. However, determining incidence is complex and requires time-consuming cohort studies or registries with date of diagnosis. Estimating incidence from pre
Externí odkaz:
https://doaj.org/article/06139bab0d6e4b108214ddd018f21ae7
Autor:
Roberto Elosua, Jose M. Ordovas, L. Adrienne Cupples, Chao-Qiang Lai, Serkalem Demissie, Caroline S. Fox, Joseph F. Polak, Philip A. Wolf, Ralph B. D'Agostino, Sr., Christopher J. O'Donnell
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 5, Pp 990-996 (2006)
Genetic variation at the apolipoprotein A5 gene (APOA5) is associated with increased triglyceride concentrations, a risk factor for atherosclerosis. Carotid intimal medial thickness (IMT) is a surrogate measure of atherosclerosis burden. We sought to
Externí odkaz:
https://doaj.org/article/58149b458b7545428f0771051665d54e
Publikováno v:
Stat Med
When comparing performances of two risk prediction models, several metrics exist to quantify prognostic improvement, including the change in the area under the Receiver Operating Characteristic curve, the Integrated Discrimination Improvement, the Ne
Autor:
Alex Dmitrienko, Ralph B. D'Agostino
Publikováno v:
Statistics in Medicine. 36:4423-4426
Publikováno v:
Statistics in Medicine. 36:3334-3360
The change in area under the curve (∆AUC), the integrated discrimination improvement (IDI), and net reclassification index (NRI) are commonly used measures of risk prediction model performance. Some authors have reported good validity of associated
Publikováno v:
Statistics in Medicine. 36:1334-1360
Clinical trials target patients who are expected to benefit from a new treatment under investigation. However, the magnitude of the treatment benefit, if it exists, often depends on the patient baseline characteristics. It is therefore important to i
Autor:
Daniel Levy, Patrice Sutherland, Geoffrey H. Tofler, Ralph B. D'Agostino, Joseph M. Massaro, Thomas Buckley
Publikováno v:
European Journal of Preventive Cardiology. 24:382-388
Background Although a higher heart rate is associated with an increased risk of cardiovascular disease, the mechanism is not well understood. As thrombosis has an important role in plaque development and acute coronary syndromes, the increase related
Publikováno v:
Statistics in Medicine. 36:4482-4490
Discrimination slope, defined as the slope of a linear regression of predicted probabilities of event derived from a prognostic model on the binary event status, has recently gained popularity as a measure of model performance. It is as a building bl
Publikováno v:
Statistics in medicineReferences. 39(22)
Statistical learning methods are widely used in medical literature for the purpose of diagnosis or prediction. Conventional accuracy assessment via sensitivity, specificity, and ROC curves does not fully account for clinical utility of a specific mod
Autor:
R. Paul Wadwa, Anwar T. Merchant, Ralph B. D'Agostino, Ronny A. Bell, Scott Isom, Elaine M. Urbina, Stephen R. Daniels, Amy S. Shah, Kristi Reynolds, Lawrence M. Dolan, Giuseppina Imperatore, Deborah A. Bowlby, Santica M. Marcovina, Dana Dabelea
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The incidence of type 1 diabetes mellitus (T1DM) in children is increasing, resulting in higher burden of cardiovascular diseases due to diabetes mellitus–related vascular dysfunction. Methods and Results We examined cardiovascular risk