Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Beka Solomon"'
Autor:
Beka Solomon, Polina Rabinovich-Toidman, María Inés Becker, Myra Gartner, Michal Arbel-Ornath
Publikováno v:
Journal of Alzheimer's Disease. 22:469-482
Among the different paradigms aimed at interfering with amyloid-β (Aβ)-related pathology, the attenuation of amyloid-β protein precursor (AβPP) processing to limit Aβ levels seems to be a promising one. Along with the development of BACE1 inhibi
Publikováno v:
Proceedings of the National Academy of Sciences. 102:7718-7723
Amyloid-beta peptide (AbetaP) that accumulates in the Alzheimer's diseased brain is derived from proteolytic processing of the amyloid precursor protein (APP) by means of beta- and gamma-secretases. The beta-secretase APP cleaving enzyme (BACE), whic
Autor:
Fidi Schwartz, Beka Solomon
Publikováno v:
Journal of Molecular Recognition. 8:72-76
The availability of monoclonal antibodies which bind to a specific antigen at distinct and well-defined sites has led to a better understanding of the effects of highly specific enzyme–antibody interactions on enzyme behaviour. By appropriate selec
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 662:191-196
Ca2+ -dependent mannose-binding proteins (MBPs) belong to the family of animal lectins. They perform in vivo as defence molecules that act as opsonins by enhancing the clearance of mannose rich pathogens and have been used in vitro for the purificati
Publikováno v:
Diabetes Care. 15:1451-1454
OBJECTIVE To develop a reliable, simple, and sensitive assay for microalbuminuria, based on covalent attachment of anti-HSA to oxirane-bearing polymethylmethacrylate beads (Eupergit CB6200). RESEARCH DESIGN AND METHODS Anti-HSA antibodies were couple
Publikováno v:
Journal of Immunoassay. 11:215-234
Two enzyme-linked immunosorbent assays were established and compared for the estimation of plasma aldosterone. In the first method immobilized aldosterone-protein complexes on the ELISA plates compete with aldosterone to be determined for the binding
Publikováno v:
Journal of neuroscience research. 84(2)
Intravenous immunoglobulin (IVIg), a purified immunoglobulin fraction manufactured from the blood of healthy humans, is an FDA-approved treatment for many immune and inflammatory diseases. Recent studies have demonstrated that IVIg therapy has severa
Autor:
Rela Koppel, Beka Solomon
Publikováno v:
Journal of biochemical and biophysical methods. 49(1-3)
Ca 2+ -dependent mannose-binding proteins (MBPs) belong to the family of animal lectins isolated from the liver and serum of rabbits, humans and rodents. They perform in vivo as defense molecules that act as opsonins by enhancing the clearance of man
Publikováno v:
Journal of neuroimmunology. 95(1-2)
Monoclonal antibodies raised against the N-terminal of Alzheimer's beta-amyloid peptide (betaAP) were found to modulate its fibrillar aggregation. While mAbs 6C6 and 10D5 inhibit the formation of beta-amyloid fibrils, trigger disaggregation and rever
Publikováno v:
Journal of inorganic biochemistry. 69(3)
Anti-aluminium monoclonal antibodies (mAbs) were prepared using aluminium chloride-bovine serum albumin complex (Al-BSA) as immunogen. Competitive enzyme-linked immunosorbant assay (ELISA), using an Al-BSA coated immunoplate, demonstrated that mice i