Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jan B. Koenderink"'
Autor:
Li Yan Qiu, Herman G.P. Swarts, Jan B. Koenderink, Jan Joep H.H.M. De Pont, Elisa C.M. Tonk, Peter H.G.M. Willems
Publikováno v:
Journal of Biological Chemistry, 281, 13533-9
Journal of Biological Chemistry, 281, 19, pp. 13533-9
Journal of Biological Chemistry, 281, 19, pp. 13533-9
Contains fulltext : 49286.pdf (Publisher’s version ) (Open Access) P-type ATPases of the IIC subfamily exhibit large differences in sensitivity toward ouabain. This allows a strategy in which ouabain-insensitive members of this subfamily are used a
Publikováno v:
Journal of Biological Chemistry, 280, 33115-22
Journal of Biological Chemistry, 280, 39, pp. 33115-22
Journal of Biological Chemistry, 280, 39, pp. 33115-22
Contains fulltext : 48560.pdf (Publisher’s version ) (Open Access) We used the baculovirus/Sf9 expression system to gain new information on the mechanistic properties of the rat non-gastric H,K-ATPase, an enzyme that is implicated in potassium home
Autor:
Gijs Schaftenaar, Herman G.P. Swarts, Peter H.G.M. Willems, Jan B. Koenderink, Elmar Krieger, Jan Joep H.H.M. De Pont, Li Yan Qiu
Publikováno v:
Journal of Biological Chemistry, 280, 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-55
Journal of Biological Chemistry, 280, 32349-55
Journal of Biological Chemistry, 280, 37, pp. 32349-32355
Journal of Biological Chemistry, 280, 37, pp. 32349-55
Journal of Biological Chemistry, 280, 32349-55
Contains fulltext : 32914.pdf (Publisher’s version ) (Open Access) Contains fulltext : 189403.pdf (Publisher’s version ) (Open Access) Although cardiac glycosides have been used as drugs for more than 2 centuries and their primary target, the sod
Autor:
Jan Joep H.H.M. De Pont, Peter H.G.M. Willems, H.P.H. Hermsen, Jan B. Koenderink, Herman G.P. Swarts
Publikováno v:
Journal of Biological Chemistry. 276:36909-36916
Several mutations of residues Glu(795) and Glu(820) present in M5 and M6 of the catalytic subunit of gastric H(+),K(+)-ATPase have resulted in a K(+)-independent, SCH 28080-sensitive ATPase activity, caused by a high spontaneous dephosphorylation rat
Publikováno v:
Biochemistry, 39, pp. 1330-1337
Biochemistry, 39, 1330-1337
Biochemistry, 39, 1330-1337
To study the role of Glu795offresent in the fifth transmembrane domain of the alpha-subunit of gastric H+,K+-ATPase, several mutants were generated and expressed in Sf9 insect cells. The E795Q mutant had rather similar properties as the wild-type enz
Publikováno v:
Insect Biochemistry and Molecular Biology, 43, 1109-15
Insect Biochemistry and Molecular Biology, 43, 12, pp. 1109-15
Insect Biochemistry and Molecular Biology, 43, 12, pp. 1109-15
Item does not contain fulltext Mutagenesis analyses and a recent crystal structure of the mammalian Na,K-ATPase have identified amino acids which are responsible for high affinity binding of cardenolides (such as ouabain) which at higher doses block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835c0cd715f9430f3119fb36a7eb0a94
http://hdl.handle.net/2066/125223
http://hdl.handle.net/2066/125223
Publikováno v:
Mechanisms and Consequences of Proton Transport ISBN: 9781461353300
The Na,K-ATPase and gastric H,K-ATPase belong to the class of P-type ATPases, which use the energy from ATP for active transport of ions. Although both X,K-ATPases share many similarities, they have different ion specificities (Na+ vs. H+) and differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2788aa76ff1ca74f78b25cdb41a3493
https://doi.org/10.1007/978-1-4615-0971-4_7
https://doi.org/10.1007/978-1-4615-0971-4_7
Autor:
Peter H.G.M. Willems, H.P.H. Hermsen, J.J.H.H.M. De Pont, Herman G.P. Swarts, Jan B. Koenderink
Na + ,K + -ATPase and gastric H + ,K + -ATPase are two related enzymes that are responsible for active cation transport. Na + ,K + -ATPase activity is inhibited specifically by ouabain, whereas H + ,K + -ATPase is insensitive to this drug. Because it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd126f985a47d1fb0c3fea66e23d973
https://europepmc.org/articles/PMC17179/
https://europepmc.org/articles/PMC17179/
Autor:
Herman G.P. Swarts, Jan Joep H.H.M. De Pont, and Peter H. G. M. Willems, Jan B. Koenderink, H.P.H. Hermsen
Publikováno v:
Biochemistry, 39, 9959-9966
Biochemistry, 39, pp. 9959-9966
Biochemistry, 39, pp. 9959-9966
A series of six different mutants (D804A, D804E, D804G, D804N, D804Q, and D804S) of aspartate 804 present in transmembrane segment 6 of the rat Na(+),K(+)-ATPase alpha(1)-subunit were prepared and expressed in Sf9 cells by use of the baculovirus expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8528a7646e2197c34ef8a55e78b08773
http://hdl.handle.net/2066/265987
http://hdl.handle.net/2066/265987
Autor:
Masatomo Maeda, Herman G.P. Swarts, M. Raijmakers, L. Wassink, F.J. Dijk, C. H. W. Klaassen, H.P.H. Hermsen, Jan B. Koenderink, J.J.H.H.M. De Pont
Publikováno v:
Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology, 1480, 182-190
Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology, 1480, pp. 182-190
Biochimica et Biophysica Acta-Protein Structure and Molecular Enzymology, 1480, pp. 182-190
It is generally assumed that negatively charged residues present in the alpha-subunit of gastric H(+),K(+)-ATPase are involved in K(+) binding and transport. Despite the fact that there is no difference between various species regarding these negativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386a411814dd6cf69f2c88dde0a713ee
http://hdl.handle.net/2066/187197
http://hdl.handle.net/2066/187197