Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Regine Heller"'
Autor:
Andreas Henke, Jürgen Rödel, Sarah Böttcher, Franziska Hornung, Michael Schacke, Mike Marquet, Bettina Löffler, Paul M. Jordan, Regine Heller, Johannes Jungwirth, Sandor Nietzsche, Alexander S. Mosig, Mathias W. Pletz, Liane Giebeler, Oliver Werz, Roland Zell, Christian Brandt, Clio Häring, Christina Ehrhardt, Stefanie Deinhardt-Emmer
Publikováno v:
Journal of Virology
SARS-CoV-2 challenges health care systems and societies worldwide in unprecedented ways. Although numerous new studies have been conducted, research to better understand the molecular pathogen-host interactions are urgently needed.
Infections wi
Infections wi
Autor:
Karoline Frieda Haupt, Zoltán Cseresnyés, Marc Thilo Figge, Maximilian Windolph, Alexander S. Mosig, Fatina Siwczak, Michael Schacke, Stefanie Deinhardt-Emmer, Christina Ehrhardt, Elisabeth Schicke, Knut Rennert, Regine Heller, Swen Carlstedt, Sandor Nietzsche, Bettina Löffler
Publikováno v:
Biofabrication
Pneumonia is one of the most common infectious diseases worldwide. The influenza virus can cause severe epidemics, which results in significant morbidity and mortality. Beyond the virulence of the virus itself, epidemiological data suggest that bacte
Autor:
Cynthia Weigel, Andreas Henke, Sara Marzo, Christina Ehrhardt, Fawad Khan, Karina Graber, Markus H. Gräler, Brigitte Glück, Regine Heller, Heena Doshi
Publikováno v:
Virus Research. 276:197835
Infections with the herpes simplex virus type 1 (HSV-1) are common and widespread. Most infections remain undetected but severe forms may develop in newborns and in immunocompromised patients. Moreover, HSV-1 might be involved in the pathogenesis of
Autor:
Cora Weigert, Kei Sakamoto, Katrin Spengler, Mark Peggie, Karina Mariño, Olga Göransson, Franck Vandermoere, Anne Knierim, Darya Zibrova, Benoit Viollet, Nicholas A. Morrice, Regine Heller
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2017, 474 (6), pp.983-1001. ⟨10.1042/BCJ20160980⟩
Biochem. J. 474, 983-1001 (2017)
Biochemical Journal, Portland Press, 2017, 474 (6), pp.983-1001. ⟨10.1042/BCJ20160980⟩
Biochem. J. 474, 983-1001 (2017)
Activation of AMP-activated protein kinase (AMPK) in endothelial cells regulates energy homeostasis, stress protection and angiogenesis, but the underlying mechanisms are incompletely understood. Using a label-free phosphoproteomic analysis, we ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9cf91a6472ceb8ae0ea89dadd05423
https://hal.archives-ouvertes.fr/hal-02366087/document
https://hal.archives-ouvertes.fr/hal-02366087/document
Autor:
Sherry N Hsieh, Qing Chang, Peter J Kuhlencordt, Gunter Ehrlich, Regine Heller, Klaus T. Preissner, Simone M. Schoenwaelder, Reinhard Wetzker, Emilio Hirsch
Publikováno v:
Cardiovascular Research. 80:96-105
Sphingosine-1-phosphate (S1P), a key regulator of vascular homeostasis and angiogenesis, promotes endothelial cell migration via stimulation of phosphoinositide 3-kinase (PI3K). The aim of this study was to identify the role of PI3Kbeta and gamma iso
Publikováno v:
European Journal of Clinical Pharmacology. 62:21-28
Oxidative stress in the vasculature has been suggested to contribute to the development of endothelial dysfunction via different mechanisms including LDL oxidation, nitric oxide (NO) scavenging, or oxidation of tetrahydrobiopterin, a critical cofacto
Publikováno v:
Annals of the New York Academy of Sciences. 1031:74-85
Nitric oxide (NO), a central regulator of vascular tone and homeostasis, is generated upon activation of endothelial NO synthase (eNOS), which is mediated by an increase of intracellular calcium and/or by eNOS phosphorylation. A reduction of NO bioav
Publikováno v:
Experimental Biology and Medicine. 228:1291-1302
In previous minireviews in this journal, we discussed work on induction of tetrahydrobiopterin biosynthesis by cytokines and its significance for nitric oxide (NO) production of intact cells as well as functions of H4-biopterin identified at this tim
Autor:
Rolf Gräbner, Ernst Malle, Regine Heller, Gunther Marsche, Alexander Nuszkowski, Anett Unbehaun
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
Hypochlorous acid/hypochlorite, generated by the myeloperoxidase/H(2)O(2)/halide system of activated phagocytes, has been shown to oxidize/modify low density lipoprotein (LDL) in vitro and may be involved in the formation of atherogenic lipoproteins
Autor:
Regine Heller, A. Kühnl, Christian Rien, Katrin Spengler, Andreas Sauerbrei, Nderim Kryeziu, Andreas Henke
Publikováno v:
Medical microbiology and immunology. 203(4)
After successful invasion of susceptible hosts, systemic distribution of coxsackievirus B3 (CVB3) most likely requires interactions with the endothelial system. Thereby, infection of endothelial cells occurs directly or viruses and/or virus-infected