Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ingrid B. Borecki"'
Autor:
Donna K. Arnett, Kari E. North, Ingrid B. Borecki, Steven C. Hunt, M. A. Province, Cora E. Lewis, Hilary Coon, Albert Oberman, R C Ellison, Michael B. Miller, Stephen S. Rich
Publikováno v:
International Journal of Obesity. 29:639-649
To conduct a full genome search for genes potentially influencing two related phenotypes: body mass index (BMI, kg/m2) and percent body fat (PBF) from bioelectric impedance in men and women. A total of 3383 participants, 1348 men and 2035 women; recr
Autor:
Tuomo Rankinen, James S. Skinner, Ingrid B. Borecki, Claude Bouchard, Mary F. Feitosa, Arthur S. Leon, D. C. Rao, Jack H. Wilmore
Publikováno v:
Metabolism. 52:35-41
The relationship between sex hormone-binding globulin (SHBG) concentrations and body fat accumulation and distribution is governed by complex dynamic factors, which may involve common genetic and/or environmental factors. The current study investigat
Autor:
Jacques Gagnon, Louis Pérusse, Treva Rice, Claude Bouchard, James S. Skinner, Dabeeru C. Rao, Greg Collier, Jack H. Wilmore, Arthur S. Leon, Yvon C. Chagnon, Ingrid B. Borecki
Publikováno v:
Obesity Research. 10:351-360
Objective: Previous studies show a wide range in the percentage of variance in leptin levels attributable to genetic factors. These studies differ markedly with respect to ethnicity, study design, and statistical methodology. Therefore, the purpose o
Autor:
Arthur S. Leon, James S. Skinner, Claude Bouchard, Dabeeru C. Rao, Ingrid B. Borecki, Ping An, Roland Rosmond, Jacques Gagnon, Jack H. Wilmore, Treva Rice, Mary F. Feitosa
Publikováno v:
Metabolism. 51:360-365
The aim of this study was to investigate whether there are familial influences on cortisol levels at baseline and in response to endurance exercise training and, if so, whether there is evidence for a major gene effect. There were 476 white individua
Autor:
Jacques Gagnon, Ping An, Tuomo Rankinen, Olavi Ukkola, Roland Rosmond, James S. Skinner, Treva Rice, Dabeeru C. Rao, Arthur S. Leon, Ingrid B. Borecki, Jack H. Wilmore, Claude Bouchard
Publikováno v:
Metabolism. 50:1315-1322
A genome-wide linkage scan was performed to identify genomic regions that influence levels of dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), and DHEA fatty acid esters (DHEA-FA) at baseline and in response to 20 weeks of endurance exercise trai
Autor:
Ani Manichaikul, Alexis C. Frazier-Wood, Dariush Mozaffarian, Nita G. Forouhi, Terho Lehtimäki, Lu Qi, J. C. M. Witteman, Julius S. Ngwa, Edmond K. Kabagambe, Caren E. Smith, Mary K. Wojczynski, Qibin Qi, Kari E. North, Ingrid B. Borecki, NJ Wareham, Mika Kähönen, Stefania Bandinelli, Georgia Saylor, Olli T. Raitakari, A.G. Uitterlinden, Frank B. Hu, F. J.A. Van Rooij, Jennifer S. Anderson, Denise K. Houston, Vera Mikkilä, Ruth J. F. Loos, Rozenn N. Lemaitre, Yongmei Liu, A. Hofman, Nicola M. McKeown, Luc Djoussé, Claudia Langenberg, Donna K. Arnett, L. A. Cupples, C M van Duijn, Kenneth J. Mukamal, Stephen B. Kritchevsky, Toshiko Tanaka, Jose M. Ordovas, Zheng Ye, Luigi Ferrucci, Jennifer A. Nettleton, Jerome I. Rotter, Y. Di Chen, M. C. Zillikens, David S. Siscovick, Michael Y. Tsai, Jorma Viikari
Publikováno v:
International Journal of Obesity, 37(9), 1211-1220. Nature Publishing Group
Low-density lipoprotein-related receptor protein 1 (LRP1) is a multi-functional endocytic receptor and signaling molecule that is expressed in adipose and the hypothalamus. Evidence for a role of LRP1 in adiposity is accumulating from animal and in v
Autor:
D. C. Rao, Michael A. Province, Aldi T. Kraja, Ulrich Broeckel, Heather A. Lawson, Lisa de las Fuentes, Ingrid B. Borecki, Steven C. Hunt, James M. Cheverud, Donna K. Arnett
Publikováno v:
Metabolism: clinical and experimental. 61(8)
Identifying metabolic syndrome (MetS) genes is important for novel drug development and health care. This study extends the findings on human chromosome 3p26-25 for an identified obesity–insulin factor QTL, with an LOD score above 3. A focused asso
Autor:
Michael A. Province, Bibiana Garcia-Bailo, Laurence D. Parnell, Michael Y. Tsai, Robert J. Straka, Donna K. Arnett, Chao-Qiang Lai, Ingrid B. Borecki, Ping An, Edmond K. Kabagambe, Jose M. Ordovas, Katherine L. Tucker
Publikováno v:
Obesity (Silver Spring, Md.). 17(3)
Adipose (adp) is an obesity gene in Drosophila and mice with crucial functions in fat metabolism. We investigated the correlation between genetic variation of the WDTC1 locus, the ortholog of adp, and human obesity. Five WDTC1 single-nucleotide polym
Autor:
James S. Pankow, Jun Wu, Mary E. Feitosa, Ingrid B. Borecki, Michael A. Province, Richard H. Myers, Russell P. Tracy, Kari E. North
It has been recognized that obese individuals are intrinsically in a state of chronic inflammation, as indicated by positive correlations between serum levels of C-reactive protein (CRP) and various anthropometric measures of obesity. To explore the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c031b731402004baa4f74f31fe6654
Autor:
Jacques Gagnon, Jack H. Wilmore, Christophe Garenc, James S. Skinner, Arthur S. Leon, Ingrid B. Borecki, Yvon C. Chagnon, D. C. Rao, Tuomo Rankinen, Louis Pérusse, Claude Bouchard
Publikováno v:
Obesity research. 11(5)
We investigated whether the Arg16Gly and Gln27Glu polymorphisms of the beta2-adrenergic receptor gene were associated with body-fat and fat-distribution phenotypes measured before and in response to a 20-week endurance-training program. BMI, fat mass