Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wim, Vanden"'
Autor:
Claudine Heinrichs, Muriel Thomas, De Schepper J, Van Hul, Ken Declerck, Geert Mortier, Olimpia Chivu, Dominique Beckers, Raoul Rooman, Silke Peeters, de Zegher F, Eveline Boudin, Koenraad Devriendt, Berghe, Wim Vanden
Publikováno v:
The journal of clinical endocrinology and metabolism
The Journal of clinical endocrinology and metabolism, Vol. 105, no. 12, p. dgaa465 (2020)
The Journal of clinical endocrinology and metabolism, Vol. 105, no. 12, p. dgaa465 (2020)
Purpose In a significant proportion of children born small for gestational age (SGA) with failure of catch-up growth, the etiology of short stature remains unclear after routine diagnostic workup. We wanted to investigate if extensive analysis of the
Autor:
Joke Vanden Berghe, Karolien De Bosscher, Jorma J. Palvimo, Guy Caljon, Charlotte Wallaeys, Ville Paakinaho, Deepika Watts, Tineke Vanderhaeghen, Bart Ghesquière, Louise Nuyttens, Lise Van Wyngene, Melanie Eggermont, Steven Timmermans, Joey De Backer, Claude Libert, Sylviane Dewaele, Wim Vanden Berghe, Jolien Vandewalle, Laura Dirkx, Ben Wielockx, Kelly Van Looveren, Rudi Beyaert, Kelly Lemeire
Publikováno v:
EMBO reports
EMBO Rep
EMBO Rep
Here, we investigate the impact of hypoxia on the hepatic response of glucocorticoid receptor (GR) to dexamethasone (DEX) in mice via RNA-sequencing. Hypoxia causes three types of reprogramming of GR: (i) much weaker induction of classical GR-respons
Autor:
Oksana Ryabtsova, Hans De Winter, Wim Vanden Berghe, Jurgen Joossens, Koen Augustyns, Pieter Van der Veken
Publikováno v:
Bioorganic and medicinal chemistry letters
The synthesis and in vitro properties of six analogues of the selective glucocorticoid receptor (GR) agonist GSK866, bearing a warhead for covalent linkage to the glucocorticoid receptor, is described.
Autor:
Tim S. Nawrot, Charlotte Vanpoucke, Nelly D. Saenen, Karen Vrijens, Bram G. Janssen, Harry Roels, Wilfried Gyselaers, Patrick De Boever, Kristof Y. Neven, Wim Vanden Berghe, Wouter Lefebvre
Publikováno v:
Environmental health perspectives
Environmental Health Perspectives
Environmental Health Perspectives
Background: Particulate matter with a diameter ≤ 2.5 μm (PM2.5) affects human fetal development during pregnancy. Oxidative stress is a putative mechanism by which PM2.5 may exert its effects. Leptin (LEP) is an energy-regulating hormone involved
Autor:
Patrick De Boever, Tim S. Nawrot, Harry A. Roels, Nelly D. Saenen, Charlotte Vanpoucke, Wim Vanden Berghe, Wilfried Gyselaers, Karen Vrijens, Bram G. Janssen, Kristof Y. Neven
Publikováno v:
ISEE Conference Abstracts. 2016
Background: Particulate matter with a diameter ≤ 2.5 µm (PM2.5) affects fetal human development during pregnancy. Oxidative stress is one putative mechanism by which PM2.5 may exert its effects. Le...
Autor:
Wim Vanden Berghe, Fatima Allie-Reid, Koch Visser, Guy Haegeman, Donita Africander, Michael Vismer, Steven Robertson, Karolien De Bosscher, Ann Louw, A Binder, Janet P. Hapgood
Publikováno v:
Journal of Biological Chemistry. 285:8061-8075
Compound A (CpdA), a dissociated glucocorticoid receptor modulator, decreases corticosteroid-binding globulin (CBG), adrenocorticotropic hormone (ACTH), and luteneinizing hormone levels in rats. Whether this is due to transcriptional regulation by Cp
Autor:
Frank, Eertmans, Olivier, De Wever, De Wever, Olivier, Willem, Dhooge, Dhooge, Willem, Wim, Vanden Berghe, Vanden Berghe, Wim, Veerle, Bogaert, Bogaert, Veerle, Marc, Bracke, Bracke, Marc, Guy, Haegeman, Haegeman, Guy, Frank, Comhaire, Comhaire, Frank, Jean-Marc, Kaufman, Kaufman, Jean-Marc
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2007, 273 (1-2), pp.16. ⟨10.1016/j.mce.2007.04.009⟩
Molecular and Cellular Endocrinology, Elsevier, 2007, 273 (1-2), pp.16. ⟨10.1016/j.mce.2007.04.009⟩
The murine, gonadotropic LbetaT2 cell line was assessed as a potential in vitro model to analyze estrogen receptor (ER)-mediated regulation of luteinizing hormone (LH) synthesis and secretion. In agreement with limited literature data, repeated expos
Publikováno v:
Molecular and Cellular Endocrinology. 221:75-85
Although medroxyprogesterone acetate (MPA) is used as an injectable contraceptive, in hormone replacement therapy (HRT) and in treatment of certain cancers, the steroid receptors and their target genes involved in the actions of MPA are not well unde
Publikováno v:
Endocrine Reviews. 24:488-522
The inflammatory response is a highly regulated physiological process that is critically important for homeostasis. A precise physiological control of inflammation allows a timely reaction to invading pathogens or to other insults without causing ove
Autor:
Wim Vanden Berghe, Robert Hooghe, E. L. Hooghe-Peters, Karolien De Bosscher, Ellinor R. S. Bauer, Bart Staels, Sabrina Devos, Guy Haegeman, Frank Roels
Publikováno v:
Biochemical Pharmacology. 65:303-308
The hematological toxicity of the commonly used triazine herbicides is a cause for concern. In a search for molecular targets of these compounds, as their effects paralleled those seen with dexamethasone (DEX), we first looked for interaction with th