Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stephanie R. Villa"'
Autor:
Annette Gilchrist, Stephanie R. Villa, Rama K. Mishra, Gary E. Schiltz, Medha Priyadarshini, Joseph L. Zapater, Helena Mancebo, Brian T. Layden
Publikováno v:
Journal of Investigative Medicine. 65:1116-1124
Critical aspects of maintaining glucose homeostasis in the face of chronic insulin resistance and type 2 diabetes (T2D) are increased insulin secretion and adaptive expansion of beta cell mass. Nutrient and hormone sensing G protein-coupled receptors
Autor:
Raghavendra G. Mirmira, Medha Priyadarshini, Charles R. Mackay, Thierry Alquier, Annette Gilchrist, Helena Mancebo, Barton Wicksteed, Vincent Poitout, Miles Fuller, Stephanie R. Villa, Brian T. Layden
Publikováno v:
Molecular Endocrinology. 29:1055-1066
G protein-coupled receptors have been well described to contribute to the regulation of glucose-stimulated insulin secretion (GSIS). The short-chain fatty acid-sensing G protein-coupled receptor, free fatty acid receptor 2 (FFAR2), is expressed in pa
Autor:
Medha Priyadarshini, Anthony R. Angueira, Maureen Gannon, Sarah A. Tersey, Miles Fuller, Bethany A. Carboneau, Tanya Bhardwaj, Annette Gilchrist, Raghavendra G. Mirmira, Rockann E. Mosser, Brian T. Layden, Michael R. Brodsky, Stephanie R. Villa, Helena Mancebo
Publikováno v:
Scientific Reports
The regulation of pancreatic β cell mass is a critical factor to help maintain normoglycemia during insulin resistance. Nutrient-sensing G protein-coupled receptors (GPCR) contribute to aspects of β cell function, including regulation of β cell ma
Autor:
Heather A. Bimonte-Nelson, Candy W. S. Tsang, Cheryl D. Conrad, B. Blair Braden, Jazmin I. Acosta, Ann N. Hoffman, Stephanie R. Villa, Julia E. Gerson, Bryan W. Camp
Publikováno v:
European Journal of Neuroscience. 36:3086-3095
After natural menopause in women, androstenedione becomes the primary hormone secreted by the residual follicle-depleted ovaries. In two independent studies, in rodents that had undergone ovarian follicular depletion, we found that higher endogenous
Autor:
Heather A. Bimonte-Nelson, Alexandra N. Garcia, Alain R. Simard, B. Blair Braden, Stephanie R. Villa, Natalie Lefort, Sarah E. Mennenga, Jazmin I. Acosta, Laszlo Prokai
Publikováno v:
Psychopharmacology. 218:405-418
The synthetic progestin medroxyprogesterone acetate (MPA), widely used in hormone therapy (HT) and as the contraceptive Depo Provera, is implicated in detrimental cognitive effects in women. Recent evidence in aged ovariectomized (Ovx) rodents shows