Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sandrine Billet"'
Publikováno v:
Kidney International. 74(11):1379-1384
Numerous clinical studies and experimental investigations using cell culture and animal models suggest that angiotensin II (AngII) via AT(1) receptor activation might induce cardiovascular hypertrophy, fibrosis and atherosclerosis resulting in vascul
Autor:
Jon W. Adams, Ellen A. Bernstein, Sebastien Fuchs, Derick Okwan-Duodu, Chentao Lin, Ping Li, Kenneth E. Bernstein, Sandrine Billet, Xiao Z. Shen, Yi Xu, Hong D. Xiao
Publikováno v:
Journal of Molecular Medicine. 86:679-684
Angiotensin-converting enzyme (ACE) has been well-recognized for its role in blood pressure regulation. ACE is made by many tissues, though it is most abundantly expressed on the luminal surface of vascular endothelium. ACE knockout mice show a profo
Autor:
Eric Clauser, Brigitte Escoubet, Evelyne Souil, Sonia Verp, Sophie Conchon, Jean Marie Gasc, Sandrine Billet, Pierre Corvol, Martine Muffat-Joly, Véronique Baudrie, Jean-Luc Elghozi, Ghislaine Hamard, Kenneth E. Bernstein, Annie Michaud, Sabine Bardin
Publikováno v:
Journal of Clinical Investigation. 117:1914-1925
The role of the renin-angiotensin system has been investigated by overexpression or inactivation of its different genes in animals. However, there is no data concerning the effect of the constitutive activation of any component of the system. A knock
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 290:E840-E848
The renin-angiotensin-aldosterone system (RAAS) is central to cardiovascular and renal physiology. However, there is no animal model in which the activation of the RAAS only reflects the activation of the angiotensin II (ANG II) AT1receptor. As a fir
Autor:
Kenneth E. Bernstein, Ryousuke Satou, Catherine Kim, Romer A. Gonzalez-Villalobos, Sandrine Billet, L. Gabriel Navar, Sebastien Fuchs
The contribution of the intrarenal renin-angiotensin system to the development of hypertension is incompletely understood. Here, we used targeted homologous recombination to generate mice that express angiotensin-converting enzyme (ACE) in the kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970037224b157cb861baad2a62dd809a
https://europepmc.org/articles/PMC3060439/
https://europepmc.org/articles/PMC3060439/
Autor:
Sebastien Fuchs, Sandrine Billet, Kenneth E. Bernstein, Derick Okwan-Duodu, Vivekanand Datta, Chentao Lin, Xiao Z. Shen, Randa Alsabeh, Xu Chen
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 25(4)
Inhibition of angiotensin-converting enzyme (ACE) induces anemia in humans and mice, but it is unclear whether ACE is involved in other aspects of hematopoiesis. Here, we systemically evaluated ACE-knockout (KO) mice and found myelopoietic abnormalit