Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Michael E Boulton"'
Publikováno v:
Nitric Oxide
Low doses of nitrite, close to physiological levels, increase blood flow in normal and ischemic tissues through a nitric oxide (NO) dependent mechanism. Given that nitrite therapy and dietary supplementation with vegetables high in nitrate (e.g. beet
Autor:
Karina C. Ricart, Xiaoping Qi, Casey D. Morrow, William Van Der Pol, Kiyoung Kim, Rakesh P. Patel, Michael E. Boulton, Marcas M. Bamman, Pamela V. O'Neal, Khandaker Ahtesham Ahmed, Gordon Fisher, Christian E. Behrens
Publikováno v:
Nitric Oxide
Reduction of salivary nitrate to nitrite by oral nitrate reductase (NR) expressing bacteria has emerged as an integral pathway in regulating nitric oxide (NO) homeostasis and signaling. The oral microbiome is critical for this pathway. Variations in
Autor:
Julia V. Busik, Michael E. Boulton, Sayak K. Mitter, Yuanqing Yan, Maria B. Grant, Xiaoping Qi
Publikováno v:
Cells
Volume 9
Issue 4
Cells, Vol 9, Iss 905, p 905 (2020)
Volume 9
Issue 4
Cells, Vol 9, Iss 905, p 905 (2020)
Retinal homeostasis is under both diurnal and circadian regulation. We sought to investigate the diurnal expression of autophagy proteins in normal rodent retina and to determine if this is impaired in diabetic retinopathy. C57BL/6J mice and Bio-Bree
Autor:
Sergio Li Calzi, Bokkyoo Jun, Nicolas G. Bazan, Nilanjana Sengupta-Caballero, Lynn C Shaw, Mircea Ivan, Nan Li, Judith Quigley, Maria B. Grant, Michael E. Boulton, Leni Moldovan, Julia V. Busik, Josef Neu
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Low levels of the long chain polyunsaturated fatty acid (LCPUFA) docosahexaenoic acid (DHA) have been implicated in retinopathy of prematurity (ROP). However, oral DHA suffers from poor palatability and is associated with increased bleeding i
Autor:
Ana Leda F. Longhini, Michael E. Boulton, Jeffrey S. Thinschmidt, Maria B. Grant, Michael A. King
Publikováno v:
Diabetes. 67
Purpose: Since loss of retinal SST and circulating SST occurs in DR, we asked if loss of hypothalamic SST production would impact the innervation and function of the BM and influence DR in T2D rat model. Methods: Brain sections of BBZ/Wor rats with 4
Autor:
Fang-I Chu, Julia V. Busik, Qiuhong Li, Gavin Y. Oudit, Yaqian Duan, Steven D. Townsend, Caitlin Ryan, Ashay D. Bhatwadekar, Xiaoxin X. Wang, Ruli Gao, Hartmut Derendorf, Ram Prasad, Fletcher A. White, Raghavendra G. Mirmira, Emil G. Moldovan, Mervin C. Yoder, Moshe Levi, Daniel Morton, Leni Moldovan, Carmella Evans-Molina, Luisa Chan, Luciano Adorini, Michael E. Boulton, Maria B. Grant, Eleni Beli, Yuanqing Yan, Cristiano P. Vieira
Publikováno v:
Diabetes. 67(9)
Intermittent fasting (IF) protects against the development of metabolic diseases and cancer, but whether it can prevent diabetic microvascular complications is not known. In db/db mice, we examined the impact of long-term IF on diabetic retinopathy (
Autor:
Tatiana E. Salazar, Ruchi J. Vyas, Sugata Hazra, Patricia Parsons-Wingerter, Yaqian Duan, Jude Al-Sabah, Troy A. Markel, Judith Quigley, Leni Moldovan, Eleni Beli, Michael E. Boulton, Dongni Feng, Sergio Li Calzi, Maria B. Grant, Alexander G. Obukhov, Gavin Y. Oudit, Matthew C. Murray, Kakarla V. Chalam, Marya Meroueh, Rehae C. Miller, Thao Trinh
Publikováno v:
Stem cells (Dayton, Ohio). 36(9)
Angiotensin-converting enzyme 2 (ACE2) is the primary enzyme of the vasoprotective axis of the renin angiotensin system (RAS). We tested the hypothesis that loss of ACE2 would exacerbate diabetic retinopathy by promoting bone marrow dysfunction. ACE2
Autor:
Gabriel Virella, Junping Chen, Maria F. Lopes-Virella, Mei Du, Yanchun Li, Dongxu Fu, Jian Xing Ma, Jeremy Y. Yu, Michael E. Boulton, Mingyuan Wu, Timothy J. Lyons, Souzan A. Abdelsamie, Ying Chen
Publikováno v:
Journal of Lipid Research. 55:860-869
Recently it has been shown that levels of circulating oxidized LDL immune complexes (ox-LDL-ICs) predict the development of diabetic retinopathy (DR). This study aimed to investigate whether ox-LDL-ICs are actually present in the diabetic retina, and
Autor:
Dmitri O. Traktuev, Phillip L. Johnson, Stephanie D. Fitz, Marcelo Febo, Mervin C. Yoder, Todd O. McKinley, Jared A. Smith, Robyn K. Fuchs, Matthew R. Richardson, Jamie Case, Lung-Ji Chang, Maria B. Grant, Jeffrey S. Thinschmidt, Emily K. Sims, Yaqian Duan, Huisheng Xie, Xinzhong Dong, Bruce McDavitt, Keith L. March, Youngsook Kim, Alicia L. Bertone, Minsu Kim, Leni Moldovan, Keith G. Avin, Luis M. Colon-Perez, Eleni Beli, John George, Zhanguo Gao, Matthew S. Ripsch, Susan P. McGorray, Sergio Li Calzi, Julie A. Mund, Stuart J. Warden, Fletcher A. White, Song Lai, Xiaolin Deng, Jingfeng Ma, Michael E. Boulton, Vaishnavi Jadhav, Anantha Shekhar, Mikhail G. Kolonin, Tatiana Salazar, Ashay D. Bhatwadekar, Yuanqing Yan
Publikováno v:
Stem cells (Dayton, Ohio). 35(5)
Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI-4 and LI-11, and GV-14 and GV-20 (humans) and Bai-hui (rats) increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mese
Autor:
Tailoi Chan-Ling, Sergio Caballero, Julia V. Busik, Yuanqing Yan, Jeffrey S. Thinschmidt, Sugata Hazra, Andrea Zsombok, Andrei V. Derbenev, Jaleel A. Miyan, Wencheng Li, Daniel R. Saban, Ping Hu, Maria Tikhonenko, Tatiana Salazar, Mohan K. Raizada, James M. Dominguez, Ashay D Bhatwadekar, Michael E. Boulton, Maria B. Grant, Susan P. McGorray
Publikováno v:
The American Journal of Pathology. 183(5):1608-1620
By using pseudorabies virus expressing green fluorescence protein, we found that efferent bone marrow-neural connections trace to sympathetic centers of the central nervous system in normal mice. However, this was markedly reduced in type 1 diabetes,