Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Makoto Endo"'
Autor:
Hiroshi Aoyama, Toshiyuki Hiramatsu, Takamitsu Hosoya, Makoto Endo, Kumi Takata, Masaaki Suzuki, Takaaki Ikemoto, Hirotaka Onoe
Publikováno v:
Diabetes
OBJECTIVE In skeletal muscles, dantrolene inhibits the exercise-induced membrane translocation of GLUT4. It has been postulated that the inhibitory action of dantrolene on Ca2+ release from the sarcoplasmic reticulum (SR) causes inhibition of exercis
Autor:
Takanobu Goto, Masahiro Hayashi, Masaharu Ukawa, Hisashi Murata, Makoto Endo, Hideo Hatate, Hirofumi Yamashita, Shusaku Takagi
Publikováno v:
Fisheries Science. 72:546-555
To elucidate the hemolytic suppression roles of taurine and the necessity of dietary taurine supplementation in yellowtail Seriola quinqueradiata fed a diet without fishmeal, juvenile fish with an initial body weight of 250 g were fed for 40 weeks in
Autor:
Takaaki Ikemoto, Makoto Endo
Publikováno v:
British Journal of Pharmacology. 134:719-728
1. To characterize the effect of clofibric acid (Clof) on the Ca(2+) release mechanism in the sarcoplasmic reticulum (SR) of skeletal muscle, we analysed the properties of Clof-induced Ca(2+) release under various conditions using chemically skinned
Autor:
Makoto Endo, Masaaki Suzuki, Hiroshi Aoyama, Yasutaka Kihara, Takamitsu Hosoya, Takaaki Ikemoto
Publikováno v:
British Journal of Pharmacology. 134:729-736
1. We analysed the effect of dantrolene (Dan) and five newly synthesized derivatives (GIFs) on Ca(2+) release from the sarcoplasmic reticulum (SR) of mouse skeletal muscle. 2. In intact muscles, GIF-0185 reduced the size of twitch contraction induced
Autor:
Tokio Yamaguchi, Hiroshi Nakajima, Kiyoshi Yamauchi, Mikio Fukudome, Hisashi Murata, Toshiyuki Shimomura, Takafumi Ito, Tadashi Sakai, Makoto Endo
Publikováno v:
Aquaculture. 160:205-214
The jaundiced yellowtail Seriola quinqueradiata had yellow discolored skin and hyperbilirubinemia. Histology revealed that hemosiderin and ceroid occurred in the spleen. In the vascular system, there were vasculitis and sinusoidal dilatation. Hepatic
Autor:
Takaaki Ikemoto, Tetsuo Noda, Makoto Endo, Hiroshi Takeshima, Miyuki Nishi, Shinji Komazaki, Masamitsu Iino
Publikováno v:
The Journal of Physiology. 501:305-312
1 We generated mice with targeted disruptions in the genes for both ryanodine receptor type 1 (RyR-1) and type 3 (RyR-3) to study the functional roles of RyR subtypes in skeletal muscle. 2 In permeabilized myocytes lacking both the RyRs, the Ca2+-ind
Publikováno v:
British Journal of Pharmacology. 118:690-694
1. Calmodulin (CaM) has a biphasic effect on Ca(2+)-induced Ca2+ release (CICR) from the sarcoplasmic reticulum (SR): potentiation and inhibition at low (pCa > 6.0) and high (pCa 5) Ca2+ concentrations, respectively. To characterize the mode of actio
Publikováno v:
The Journal of Physiology. 487:573-582
1. We analysed the effect of calmodulin on Ca(2+)-induced Ca2+ release (CICR) in the sarcoplasmic reticulum (SR) using chemically skinned fibres of rabbit psoas muscle. Ca2+ release was measured using fura-2 microfluorometry. 2. In saponin-skinned fi
Critical intracellular Ca2+ concentration for all-or-none Ca2+ spiking in single smooth muscle cells
Publikováno v:
The EMBO Journal. 12:5287-5291
Neurotransmitters induce contractions of smooth muscle cells initially by mobilizing Ca2+ from intracellular Ca2+ stores through inositol 1,4,5-trisphosphate (InsP3) receptors. Here we studied roles of the molecules involved in Ca2+ mobilization in s
Publikováno v:
The Journal of Physiology. 470:335-348
1. We studied the effects of ryanodine on the functions of the sarcoplasmic reticulum (SR) in skinned muscle fibres from Xenopus laevis. 2. Ryanodine treatment decreased the Ca2+ uptake capacity of the SR in a fixed Ca2+ loading condition. The extent