Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Jose C. Florez"'
Autor:
Camille E Powe, Joseph J Locascio, Larraine Huston Gordesky, Jose C Florez, Patrick M Catalano
Publikováno v:
J Clin Endocrinol Metab
Background Oral glucose tolerance test (OGTT)-based measures of insulin secretory response have not been validated in pregnancy. Methods In a secondary analysis of a longitudinal study, participants were studied prepregnancy (n = 40), in early pregna
Publikováno v:
The Journal of clinical endocrinology and metabolism.
Context MicroRNAs (miRs) are short (ie, 18-26 nucleotide) regulatory elements of messenger RNA translation to amino acids. Objective The purpose of this study was to assess whether miRs are predictive of incident type 2 diabetes (T2D) in the Diabetes
Publikováno v:
J Clin Endocrinol Metab
Context Polymorphisms in the gene encoding the glucagon-like peptide-1 receptor (GLP1R) are associated with type 2 diabetes but their effects on incretin levels remain unclear. Objective We evaluated the physiologic and hormonal effects of GLP1R geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbe6672e0a9bb1ed31ef2576bb419de
https://europepmc.org/articles/PMC9387717/
https://europepmc.org/articles/PMC9387717/
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:e3965-e3966
Autor:
Tove Fall, Anubha Mahajan, Dmitry Shungin, B. Balkau, Gerjan Navis, A. Metspalu, Anneli Pouta, Andrew A. Hicks, Ilja M. Nolte, Ian Ford, Aroon D. Hingorani, Stefan R Bornstein, Anuj Goel, Rona J. Strawbridge, Niek Verweij, Sarah H. Wild, Patricia B. Munroe, T.B. Harris, Jaana Lindström, Johnson Pcd., Nita G. Forouhi, Pierre Meneton, Patricia A. Peyser, Sarin A-P., Andrea Ganna, Timothy M. Frayling, Patrik K. E. Magnusson, Joanne M. Meyer, Yongmei Liu, Jeanette M. Stafford, Christian Herder, L Zudina, Maria G. Stathopoulou, May E. Montasser, Nicholas D. Hastie, Inês Barroso, Schwarz Peh., James B. Meigs, Perttu Salo, George Davey Smith, Gonneke Willemsen, Christopher J. Groves, Erik P A Van Iperen, M. A. Province, Veikko Salomaa, Naveed Sattar, Serena Sanna, Maria Dimitriou, Joop Jukema, Ulrika Krus, Albert V. Smith, Markku Laakso, James F. Wilson, George Nicholson, Loic Yengo, Tatijana Zemunik, Per Eriksson, Harold Snieder, Peter P. Pramstaller, Claudia Langenberg, R. Rauramaa, Alan R. Shuldiner, Pau Navarro, Veronique Vitart, Ross M. Fraser, Aaron Isaacs, C. Lecoeur, Jesper R. Gådin, Jackie F. Price, Letizia Marullo, L.F. Bielak, Sirkka Keinänen-Kiukaanniemi, Amélie Bonnefond, Michael Stumvoll, Alessia Faggian, Anke Tönjes, Tomohiro Tanaka, Wieland Kiess, Harry Campbell, Josée Dupuis, David Altshuler, João Fadista, Winfried März, G K Hovingh, Thomas Illig, Toby Johnson, H Grallert, Kari Stefansson, Reedik Mägi, Palmer Cna., de Geus Ejcn., Martina Müller-Nurasyid, Karen Kapur, Philippe Froguel, Dorret I. Boomsma, Anders Franco-Cereceda, Marcus E. Kleber, Boehnke M, Olga D. Carlson, Ozren Polasek, Andrew P. Morris, Alex S. F. Doney, Najaf Amin, Sara M. Willems, Vilmundur Gudnason, Jose C. Florez, Jeffery R. O'Connell, Nancy L. Pedersen, T. Saaristo, Wolffenbuttel Bhr., M. I. J. Uusitupa, Longda Jiang, Iva Miljkovic, James S. Pankow, Caroline Hayward, Hugh Watkins, Vasiliki Lagou, Johanna Kuusisto, Jaakko Tuomilehto, Alan F. Wright, Josephine M. Egan, Perry Jrb., C M van Duijn, Valeriya Lyssenko, Leif Groop, Stefania Bandinelli, Nigel W. Rayner, Tõnu Esko, Stela McLachlan, Momoko Horikoshi, Eric Boerwinkle, Rick Jansen, Richard N. Bergman, Gudmar Thorleifsson, Lyle J. Palmer, Vilmantas Giedraitis, Peter Kovacs, Nicholas J. Wareham, Luigi Ferrucci, N J Timpson, D Rybin, Anne U. Jackson, Tiinamaija Tuomi, Gonçalo R. Abecasis, Harst Pvd., Meena Kumari, Albert Hofman, Chiara Scapoli, Evelin Mihailov, Josine L. Min, Anders Hamsten, Hottenga J-J., Loos Rjf., Lars Lind, Ulf de Faire, Jaakko Kaprio, Guo Li, Beate St Pourcain, C Gieger, Amanda J. Bennett, Anna Ulrich, Nabila Bouatia-Naji, Satu Männistö, Antigone S. Dimas, Jarvelin M-R., Günther Silbernagel, F Karpe, A. Körner, David S. Siscovick, M Blüher, Rebecca J. Webster, Erik Ingelsson, Susan Campbell, Mika Kivimäki, Laura J. Rasmussen-Torvik, Heikki A. Koistinen, Sophie Visvikis-Siest, Bernhard O. Boehm, Inga Prokopenko, Ping An, Emmanouil T. Dermitzakis, Cecilia M. Lindgren, Kardia Slr., Richa Saxena, Igor Rudan, Richard M. Watanabe, Jian'an Luan, Marika Kaakinen, Shin S-Y., George Dedoussis, Panagiotis Deloukas, Mark I. McCarthy, Barbara Thorand, B.W.J.H. Penninx, Peter Vollenweider, Paul W. Franks, Leena Kinnunen, Markus Perola, Yvonne Boettcher, Timo A. Lakka, Nicole Soranzo, Stavroula Kanoni, Bakker Sjl., Winkelmann Br
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 2021, 12 (1), pp.24. ⟨10.1038/s41467-020-19366-9⟩
Nature Communications, 12(1):24, 1-18. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications, 12(1):24. Nature Publishing Group
Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9
Nature Communications, 12(1):24. Nature Publishing Group UK
Lagou, V, Mägi, R, Hottenga, J J, Jansen, R, Min, J L, Willemsen, G, De Geus, E J C N, Penninx, B W, Boomsma, D I, Barroso, I, Morris, A P, Prokopenko, I & MAGIC Collaboration 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24, pp. 1-18 . https://doi.org/10.1038/s41467-020-19366-9
Min, J L, St Pourcain, M U B, Timpson, N J, Davey Smith, G, Prokopenko, I & et al. 2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, 24 . https://doi.org/10.1038/s41467-020-19366-9
2021, ' Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability ', Nature Communications, vol. 12, no. 1, 24 . https://doi.org/10.1038/s41467-020-19366-9, https://doi.org/10.1038/s41467-021-21276-3
Nature communications, vol. 12, no. 1, pp. 24
Nature Communications, 12(1). NATURE RESEARCH
Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epidemiological studies established a higher prevalence of impaired fasting glucose in men and impaired glucose tolerance in women, however, the genetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5783e9d2579548e3deb52d1bbdf19db
https://hal.univ-lorraine.fr/hal-03105716
https://hal.univ-lorraine.fr/hal-03105716
Autor:
Peitao Wu, Giulianini Franco, Daniel I. Chasman, Jerome I. Rotter, Georgy Hindy, Tom G. Richardson, M. Arfan Ikram, Ping An, Rafael R C Cuadrat, Jørgen K. Kanters, Sridharan Raghavan, Paul M. Ridker, Rita R. Kalyani, Jonas L. Isaksen, Morten S. Olesen, Xiuqing Guo, André G. Uitterlinden, Marju Orho-Melander, Lluís Masana, Lisa R. Yanek, Iyas Daghlas, Mohsen Ghanbari, Mary F. Feitosa, Jennifer A. Brody, Jose C Florez, Ulrika Ericson, James S. Floyd, Bianca Porneala, Jianwen Cai, Dhananjay Vaidya, Jee-Young Moon, James B. Meigs, George Davey Smith, Ching-Ti Liu, Susanne Jäger, Maryam Kavousi, Josée Dupuis, Christina Ellervik, Qibin Qi, Fariba Ahmadizar, Matthias B. Schulze, Mark O. Goodarzi, Dipender Gill, Josep M Mercader, Bruce M. Psaty, Laura M. Raffield, Leslie A. Lange, Colleen M. Sitlani, Robert C. Kaplan, Jie Yao, Jordi Merino, Michael A. Province
Publikováno v:
Wu, P, Moon, J-Y, Daghlas, I, Franco, G, Porneala, B C, Ahmadizar, F, Richardson, T G, Isaksen, J L, Hindy, G, Yao, J, Sitlani, C M, Raffield, L M, Yanek, L R, Feitosa, M F, Cuadrat, R R C, Qi, Q, Arfan Ikram, M, Ellervik, C, Ericson, U, Goodarzi, M O, Brody, J A, Lange, L, Mercader, J M, Vaidya, D, An, P, Schulze, M B, Masana, L, Ghanbari, M, Olesen, M S, Cai, J, Guo, X, Floyd, J S, Jäger, S, Province, M A, Kalyani, R R, Psaty, B M, Orho-Melander, M, Ridker, P M, Kanters, J K, Uitterlinden, A, Davey Smith, G, Gill, D, Kaplan, R C, Kavousi, M, Raghavan, S, Chasman, D I, Rotter, J I, Meigs, J B, Florez, J C, Dupuis, J, Liu, C-T & Merino, J 2022, ' Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol ', Diabetes Care, vol. 45, no. 1, pp. 232-240 . https://doi.org/10.2337/dc21-1284
Diabetes Care
Diabetes Care, 45(1), 232-240. American Diabetes Association Inc.
Diabetes Care
Diabetes Care, 45(1), 232-240. American Diabetes Association Inc.
OBJECTIVE LDL cholesterol (LDLc)-lowering drugs modestly increase body weight and type 2 diabetes risk, but the extent to which the diabetogenic effect of lowering LDLc is mediated through increased BMI is unknown. RESEARCH DESIGN AND METHODS We cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec7b0060cf74d3856c84b0064ada0e0
https://doi.org/10.2337/figshare.16826305.v1
https://doi.org/10.2337/figshare.16826305.v1
Autor:
Sarah Jeanfavre, Kerry A. Pierce, Eitan Hoch, Alina Ainbinder, Suzanne B.R. Jacobs, Federico Centeno-Cruz, Courtney Dennis, Karen Gelinas-Roa, Amy Deik, Lorena Orozco, Patricia Glover, Kevin Bullock, Jesse Krejci, Francisco Barajas-Olmos, Anthony N. Hollenberg, Jose C. Florez, Carlos Zerrweck, Liping Zhao, Clary B. Clish, Eric S. Lander, Jinyoung Choi, Alycen Harney, Victor Rusu
SUMMARYGenetic variation at the SLC16A11 locus contributes to the disproportionate impact of type 2 diabetes (T2D) on Latino populations. We recently demonstrated that T2D risk variants reduce SLC16A11 liver expression and function of MCT11, the mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe176c8174e9997c0a00611592c8eb5f
https://doi.org/10.1101/2021.09.08.459307
https://doi.org/10.1101/2021.09.08.459307
Autor:
Laura N. Brenner, James B. Meigs, Jose C. Florez, Aaron Leong, Josep M. Mercader, Joanne B. Cole
Publikováno v:
PLoS Medicine
PLoS Medicine, Vol 18, Iss 3, p e1003553 (2021)
medRxiv
PLoS Medicine, Vol 18, Iss 3, p e1003553 (2021)
medRxiv
Background Epidemiological studies report associations of diverse cardiometabolic conditions including obesity with COVID-19 illness, but causality has not been established. We sought to evaluate the associations of 17 cardiometabolic traits with COV
Autor:
Luz E. Guillen Pineda, Ernesto Roldan-Valadez, Jannette Furuzawa-Carballeda, Suzanne B.R. Jacobs, Patricia Clark, Ivette Cruz-Bautista, Ma. Luisa Ordonez-Sanchez, Alexandro J Martagón Rosado, Jose C. Florez, Elena Zambrano, Tannia Viveros Ruiz, Paloma Almeda-Valdes, Joaquin Azpiroz, Alicia Huerta-Chagoya, Donaji V Gómez Velasco, Magdalena del Rocío Sevilla-González, Claudia J Bautista, Carlos A. Aguilar-Salinas, Karen Guadalupe Rodríguez-Álvarez, Liliana Muñoz Hernandez, Hortensia Moreno-Macías, Miguel Herrera-Hernandez, Olimpia Arellano Campos, Geoffrey A. Walford, María Teresa Tusié Luna, Omar Yaxmehen Bello-Chavolla
Publikováno v:
European Journal of Endocrinology. 180:99-107
Objective A haplotype at chromosome 17p13 that reduces expression and function of the solute carrier transporter SLC16A11 is associated with increased risk for type 2 diabetes in Mexicans. We aim to investigate the detailed metabolic profile of SLC16
Autor:
Marie-France Hivert, Jose C. Florez, Michael Nodzenski, Catherine Allard, Luigi Bouchard, Denise M. Scholtens, Camille E. Powe, Catherine M. Briggs, Marysa V. Leya, Patrice Perron, William L. Lowe, Octavious Talbot
Publikováno v:
Diabetes
Many common genetic polymorphisms are associated with glycemic traits and type 2 diabetes (T2D), but knowledge about genetic determinants of glycemic traits in pregnancy is limited. We tested genetic variants known to be associated with glycemic trai