Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ji, Ke"'
Publikováno v:
Science China. Life sciences. 64(7)
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit prostaglandin (PG) formation by targeting cyclooxygenase (COX) 1 and 2. Long-term use of NSAIDs that selectively inhibit COX2 increases the risk for thrombotic events, cardiac failure, and hypert
Autor:
Jia Luo, Jacqueline A. Frank, Haiping Wang, Fanmuyi Yang, Zun-Ji Ke, Zhenhua Ren, Siying Wang, Xin Wang, Mei Xu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:2746-2761
Ethanol exposure during development causes fetal alcohol spectrum disorders (FASD). A large body of evidence shows that ethanol produces multiple abnormalities in the developing central nervous system (CNS), such as smaller brain size, reduced volume
Publikováno v:
Molecular Neurobiology. 54:5440-5448
Thiamine (vitamin B1) is an essential nutrient and indispensable for normal growth and development of the organism due to its multilateral participation in key biochemical and physiological processes. Humans must obtain thiamine from their diet since
Publikováno v:
Oncotarget
// Zhenhua Ren 1,2 , Xin Wang 2 , Mei Xu 2 , Fanmuyi Yang 2 , Jacqueline A. Frank 2 , Zun-ji Ke 3 and Jia Luo 2,3 1 Department of Anatomy, School of Basic Medicine, Anhui Medical University, Hefei, China 2 Department of Pharmacology and Nutritional S
Publikováno v:
Ann Transl Med
BACKGROUND: Ulcerative colitis (UC) is a non-specific chronic intestinal inflammatory disease with unclear etiology. Previous studies have suggested that the imbalance of Treg/Thl7 cells may be involved in the development of UC. It was found that 6-g
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Heavy alcohol exposure causes profound damage to the adolescent brain, particularly the hippocampus, which underlie some behavioral deficits. However, the underlying molecular mechanisms remain inconclusive. The current study sought to determine whet
Publikováno v:
Neurological Research. 36:224-233
The herbal extract 3-n-butylphthalide (NBP) is used in clinical practice for ischemic patients in China. It has been shown to have various neuroprotective effects both in vitro and in vivo. In the present study, the effects of NBP on learning and mem
Autor:
Xianglin Shi, Zhenhua Ren, Fanmuyi Yang, Yongchao Wang, Jia Luo, Xin Wang, Zun-Ji Ke, Jacqueline A. Frank, Mei Xu, Zhuo Zhang
Alcohol abuse increases the risk for pancreatitis. The pattern of alcohol drinking may impact its effect. We tested a hypothesis that chronic ethanol consumption in combination with binge exposure imposes more severe damage to the pancreas. C57BL/6 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fcaedf88d24e0bd4732f9c00e231a4
https://europepmc.org/articles/PMC5023495/
https://europepmc.org/articles/PMC5023495/
Publikováno v:
Neuroscience. 167:174-184
The protective effect of an iridoid catalpol extracted and purified from the traditional Chinese medicinal herb Rehmannia glutinosa on the neuronal degeneration of nigral-striatal dopaminergic pathway was studied in a chronic 1-methyl-4-phenyl-1,2,3,
Autor:
Lety Gonzalez, Wen-Jun Li, Jia You, Wenxia Li, Yong(刘勇) Liu, Cai Li, Lei Jiang, Zun-Ji Ke, Guoqing Yang, Yue Yu, Xinxin Yu
Publikováno v:
Molecular and Cellular Biology. 30:1650-1659
Leptin regulates energy homeostasis through central activation of multiple signaling pathways mediated by Ob-Rb, the long form of leptin receptor. Leptin resistance underlies the pathogenic development of obesity, which is closely associated with env