Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hisashi Oishi"'
Autor:
Kaushalya Kulathunga, Shayida Maimaiti, Masami Ojima, Hisashi Oishi, Ryusuke Koshida, Satoru Takahashi
Publikováno v:
Experimental Animals. 68:435-442
Mammalian postnatal growth is regulated primarily by the growth hormone (GH)/insulin-like growth factor I (IGF-I) axis. MafB is a basic leucine zipper (bZip) transcription factor that has pleiotropic functions. Although MafB plays a critical role in
Autor:
Abdelaziz E. Ibrahim, Youhei Hiromori, Megumi C. Katoh, Tsuyoshi Nakanishi, Hisashi Oishi, Al-Sayed Al-Soudy, Seiya Mizuno, Fumihiro Sugiyama, Atsushi Yoshiki, Walaa A Basha, Hossam H. Shawki, Satoru Takahashi, Yoshikazu Hasegawa, Hany A. El-Shemy, Hiroyoshi Iseki, Hisamitsu Nagase
Publikováno v:
genesis. 54:389-397
Spermatogenesis is a complex and highly regulated process by which spermatogonial stem cells differentiate into spermatozoa. To better understand the molecular mechanisms of the process, the Cre/loxP system has been widely utilized for conditional ge
Autor:
Satoru Takahashi, Chioma M. Ugboma, Yunshin Jung, Hisashi Oishi, Walaa A Basha, Miki Shimbo, Akihiro Kuno, Takashi Kudo, Megumi C. Katoh
Publikováno v:
Molecular and cellular biology. 38(8)
The MafB transcription factor is expressed in pancreatic α and β cells during development but becomes exclusive to α cells in adult rodents. Mafb-null (Mafb-/- ) mice were reported to have reduced α- and β-cell numbers throughout embryonic devel
Autor:
Megumi C. Katoh, Ahmed A. H. Abdellatif, Satoru Takahashi, Salah E. El-Morsy, Gulibaikelamu Xiafukaiti, Hisashi Oishi, Takashi Kudo, Yu-Hsin Chang, Kiyohito Ogata
Publikováno v:
Experimental Animals
The members of the MAF family of transcription factors are homologs of v-Maf -the oncogenic component of the avian retrovirus AS42. The MAF family is subdivided into 2 groups, small and large MAFs. To elucidate the role of the large MAF transcription
Autor:
Satoru Takahashi, Wataru Nishimura, Kazuki Yasuda, Hisashi Oishi, Nobuaki Funahashi, Toshiyoshi Fujiwara
Publikováno v:
Endocrine Journal. 62:37-51
MafA and MafB are basic leucine zipper transcription factors expressed in mature pancreatic β- and α-cells, respectively. MafA is not only an insulin gene transcription factor but is also critical for the maturation and maintenance of β-cell funct
Autor:
Satoru Takahashi, Margarete M. S. Heck, Jeffrey K Usui, Hisashi Oishi, Yunshin Jung, Ruyi Zhou, Toshiki Kato, Masafumi Muratani
Publikováno v:
Endocrinology. 159(2)
Adenoviral gene transfer of key β cell developmental regulators including Pdx1, Neurod1, and Mafa (PDA) has been reported to generate insulin-producing cells in the liver. However, PDA insulin secretion is transient and glucose unresponsive. Here, w
Publikováno v:
Biochemical and biophysical research communications. 483(1)
The choroid plexus (ChP) is a non-neural epithelial tissue that produces cerebrospinal fluid (CSF). The ChP differentiates from the roof plate, a dorsal midline structure of the neural tube. However, molecular mechanisms underlying ChP development ar
Autor:
Takashi Moriguchi, Miwako Kajihara, Michito Hamada, Satoru Takahashi, Masayuki Yamamoto, Ritsuko Esaki, Hisashi Oishi, Kazuteru Hasegawa, Chuan Zhang, Homare Shimohata, James Douglas Engel, Ayako Harada, Naoki Morito, Takashi Kudo
Publikováno v:
Molecular and Cellular Biology. 25:4969-4976
MafA is a transcription factor that binds to the promoter in the insulin gene and has been postulated to regulate insulin transcription in response to serum glucose levels, but there is no current in vivo evidence to support this hypothesis. To analy
Autor:
Masashi Yanagisawa, Yoshiharu Miyamoto, Joji Yamamoto, Mitsuyo Okazaki, Katsumi Imaizumi, Shinichi Usui, Minoru Okubo, Takahiro Fujino, Hisashi Oishi, Yukio Ikeda, Masao Ono, Kenta Magoori, Hiroko Tomoyori, Hideyuki Sone, Sadao Takahashi, Shinji Takada, Masato Nose, Akihisa Kamataki, Hiroshi Asaba, Ryoichi X. Ioka, Juro Sakai, Toshio Murase, Dong Ho Kim, Tokuo T. Yamamoto, Man Jong Kang
Publikováno v:
Proceedings of the National Academy of Sciences. 100:229-234
A Wnt coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) plays an essential role in bone accrual and eye development. Here, we show that LRP5 is also required for normal cholesterol and glucose metabolism. The production of mice lac
Autor:
Satoru Takahashi, Masaki Hiramoto, Wataru Nishimura, Kazuki Yasuda, Miho Kawaguchi, Hisashi Oishi, Koki Eto, Toshiyoshi Fujiwara, Haruhide Udagawa
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104184 (2014)
PLoS ONE
PLoS ONE
The postnatal proliferation and maturation of insulin-secreting pancreatic β-cells are critical for glucose metabolism and disease development in adults. Elucidation of the molecular mechanisms underlying these events will be beneficial to direct th