Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Hideo, Izawa"'
Autor:
Hideki Ishii, Toshimitsu Niwa, Kyosuke Takeshita, Soichiro Kumagai, Susumu Suzuki, Hideo Izawa, Daiji Yoshikawa, Toyoaki Murohara, Mutsuharu Hayashi
Publikováno v:
Circulation Journal. 78:2477-2482
Background:Indoxyl sulfate (IS), a uremic toxin, has cardiovascular as well as uremic toxicity. We evaluated the prognostic value of blood IS level for long-term outcome.Methods and Results:This study followed 311 patients with coronary artery diseas
Autor:
Gen Ukai, M Nomura, Kohsuke Kinoshita, Yukio Ozaki, Hiroatsu Yokoi, Junichi Ishii, Shin Ichiro Morimoto, Hideo Izawa, Wakaya Fujiwara, Daisuke Mukaide
Publikováno v:
Heart and Vessels. 28:316-322
Previous studies have shown highly effective lowering of blood pressure with thiazide diuretics in combination with angiotensin receptor blockers. However, thiazide diuretics may cause the development of diabetes and abnormal lipid metabolism. Little
Autor:
Takao Nishizawa, Xian Wu Cheng, Akiko Noda, Akihiro Hirashiki, Kyosuke Takeshita, Koji Obata, Takeshi Sasaki, Kohzo Nagata, Hideo Izawa, Guo-Ping Shi, Zhehu Jin, Toyoaki Murohara, Masafumi Kuzuya, Kenji Okumura
Publikováno v:
Journal of Hypertension. 28:1515-1526
Background The beneficial cardiac effects of some Ca(2+) channel blockers have been attributed to blood pressure reduction, but these pleiotropic effects require further investigation. We compared the effects of benidipine, which has beneficial cardi
Autor:
Masafumi Kitakaze, Hatsue Ishibashi-Ueda, Tomoko S. Kato, Hideo Izawa, Yoshihiko Ikeda, Kazuhiko Hashimura, Taka Aki Matsuyama, Kazuo Komamura, Masaki Asakura, Takeshi Nakatani, Toshiaki Shishido, Mitsuhiro Yokota, Yusuke Sata, Soichiro Kitamura
Publikováno v:
International Heart Journal. 51:259-263
The aim of the present study was to investigate the relationship between rejections and gene expression of Ca(2+)-handling proteins in heart transplant recipients. Thirty-seven heart transplant recipients underwent routine endomyocardial biopsy. Leve
Autor:
Toyoaki Murohara, Masakazu Kobayashi, Masahiro Nakatochi, Kohzo Nagata, Tatsuaki Matsubara, Keiko Naruse, Hideo Izawa, Satoshi Shintani, Mitsuhiro Yokota, Akihiro Hirashiki, Takao Nishizawa, Hiroyuki Asano, Daisuke Tanimura
Publikováno v:
Diabetologia. 53:234-246
Aims/hypothesis Resistin is a cytokine derived from adipose tissue and is implicated in obesity-related insulin resistance and type 2 diabetes mellitus. Polymorphisms of the resistin gene (RETN) have been shown to affect the plasma resistin concentra
Autor:
Hirotaka Kimata, Akiko Noda, Masako Saka, Xian Wu Cheng, Sahoko Ichihara, Hideo Izawa, Kohzo Nagata, Mitsuhiro Yokota, Koji Obata
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 33:1164-1171
SUMMARY 1 Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) manifest pleiotropic effects that may contribute to their therapeutic efficacy. However, the mechanism of the beneficial action of statins on cardiac hypertrophy and fi
Autor:
Takahiro Kimata, Xian Wu Cheng, Guo-Ping Shi, Eri Asai, Kohzo Nagata, Masako Saka, Hideo Izawa, Mitsuhiro Yokota, Akiko Noda, Toyoaki Murohara, Hai Jin, Tetsuro Nagasaka, Kae Nakamura, Masafumi Kuzuya, Akihisa Iguchi, Koji Obata
Publikováno v:
Hypertension. 48:979-987
Cathepsins are cysteine proteases that participate in various types of tissue remodeling. However, their expressions during myocardial remodeling have not been examined. In this study, we investigated their expressions in the left ventricular (LV) my
Autor:
Kohzo Nagata, Takao Nishizawa, Xian Wu Cheng, Toyoaki Murohara, Hirotaka Kimata, Masako Saka, Hideo Izawa, Koji Obata, Mitsuhiro Yokota, Akiko Noda, Sahoko Ichihara
Publikováno v:
Journal of Cardiovascular Pharmacology. 47:770-779
Statin therapy may be associated with lower mortality in patients with heart failure, but the underlying mechanism of such an association is unknown. We have evaluated the effects of pitavastatin on cardiac function and survival in a rat model of hyp
Autor:
Tetsuro Nagasaka, Kohzo Nagata, Hideo Izawa, Jinglan Xu, Mitsunori Iwase, Mitsuhiro Yokota, Tomoki Naoe, Koji Obata, Toyoaki Murohara, Akiko Noda, Sahoko Ichihara
Publikováno v:
Hypertension. 46:719-724
Long-term administration of vasodilators increases shear stress, which is thought to be important for vascular growth in the heart. Nicorandil, an activator of ATP-sensitive potassium channels with a nitrate-like action, is a potent vasodilator. We h
Publikováno v:
Molecular Genetics and Metabolism. 81:282-290
Given that a substantial proportion of individuals with coronary artery disease (CAD) also have type 2 diabetes, it is important to identify genes that confer susceptibility to CAD independently in subjects with type 2 diabetes and in those without t