Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elisa Araldi"'
Autor:
Yajaira Suárez, Christina Echagarruga, Emilie Montenont, Elisa Araldi, Nicole Allen, Jeffrey S. Berger
Publikováno v:
Blood. 128:2033-2042
Platelet activity plays a major role in hemostasis with increased platelet activity likely contributing to the pathogenesis of atherothrombosis. We sought to identify associations between platelet activity variability and platelet-related genes in he
Autor:
Erinn B. Rankin, Richa Khatri, Laura Mangiavini, Ernestina Schipani, Elisa Araldi, Rita Gerard-O'Riley, Amato J. Giaccia, Christophe Merceron, Tremika L.S. Wilson
Publikováno v:
Developmental Biology. 393(1):124-136
Adaptation to low oxygen tension (hypoxia) is a critical event during development. The transcription factors Hypoxia Inducible Factor-1α (HIF-1α) and HIF-2α are essential mediators of the homeostatic responses that allow hypoxic cells to survive a
Autor:
Abhishek Singh, Carlos Fernández-Hernando, Nathan L. Price, Gerald I. Shulman, Leigh Goedeke, Rafael de Cabo, Alberto Diaz-Ruiz, Allison Wing, Noemi Rotllan, Yajaira Suárez, Ángel Baldán, Matthew S. Rodeheffer, Elisa Araldi, Joao Paulo Camporez, Alberto Canfrán-Duque
Publikováno v:
Cell reports
Cell Reports, Vol 22, Iss 8, Pp 2133-2145 (2018)
Cell Reports, Vol 22, Iss 8, Pp 2133-2145 (2018)
SUMMARY While therapeutic modulation of miRNAs provides a promising approach for numerous diseases, the promiscuous nature of miRNAs raises concern over detrimental off-target effects. miR-33 has emerged as a likely target for treatment of cardiovasc
Autor:
Erinn B. Rankin, Elisa Araldi, Amato J. Giaccia, Tremika L.S. Wilson, Jenny Yuan, Colleen Wu, Andrew L. Rankin, Ernestina Schipani, Rebecca E. Andersen, Richa Khatri, Calvin J. Kuo
Publikováno v:
Cell. 149(1):63-74
Summary Osteoblasts are an important component of the hematopoietic microenvironment in bone. However, the mechanisms by which osteoblasts control hematopoiesis remain unknown. We show that augmented HIF signaling in osteoprogenitors results in HSC n
Autor:
Ernestina Schipani, Elisa Araldi
Publikováno v:
Bone. 47:190-196
Oxygen is not only an obviously important substrate, but it is also a regulatory signal that controls expression of a specific genetic program. Crucial mediator of the adaptive response of cells to hypoxia is the family of Hypoxia-Inducible Transcrip
Autor:
Jungsu Kim, Alexander V. Vlassov, Carlos Fernández-Hernando, Alberto Dávalos, Mu Li, Leigh Goedeke, Amarylis C. B. A. Wanschel, Juan F. Aranda, Cristina M. Ramírez, Daniel Cirera-Salinas, Elisa Araldi, Antonio Castrillo, Yajaira Suárez, Jiri Zavadil, Noemi Rotllan, Alessandro Salerno
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
PMCID: PMC3929583.-- et al.
[Rationale]: Foam cell formation because of excessive accumulation of cholesterol by macrophages is a pathological hallmark of atherosclerosis, the major cause of morbidity and mortality in Western societies. Liver X
[Rationale]: Foam cell formation because of excessive accumulation of cholesterol by macrophages is a pathological hallmark of atherosclerosis, the major cause of morbidity and mortality in Western societies. Liver X
Autor:
Elisa Araldi, Cristina M. Ramírez, Derek S. Gilchrist, Mariola Kurowska-Stolarska, Carlos Fernández-Hernando, Jagtar Singh Nijjar, Christopher A. Lavery, Iain B. McInnes, Ashley M. Miller
Publikováno v:
PLoS ONE; Vol 8
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72324 (2013)
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e72324 (2013)
Hepatic steatosis is a global epidemic that is thought to contribute to the pathogenesis of type 2 diabetes. MicroRNAs (miRs) are regulators that can functionally integrate a range of metabolic and inflammatory pathways in liver. We aimed to investig