Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ayako Suzuki"'
Autor:
Jun Zhang, Roger J. Davis, Meng Li, Christopher Q. Chen, Anna Mae Diehl, Mariam Aghajan, Ying Wang, Robert Win Maw Min, Tin Aung Than, Sanda Win, Neil Kaplowitz, Yibu Chen, Manal F. Abdelmalek, Filbert W.M. Aung, Ayako Suzuki
Publikováno v:
Journal of Clinical Investigation. 129:5278-5293
SH3 domain–binding protein that preferentially associates with Btk (SAB) is an outer-membrane docking protein for JNK-mediated impairment of mitochondrial function. Deletion of Sab in hepatocytes inhibits sustained JNK activation and cell death. Th
Autor:
Sanda Win, Neil Kaplowitz, Brad Wanken, Ying Wang, Robert W.M. Min, Meng Li, Gary Kanel, Filbert W.M. Aung, Ayako Suzuki, Yibu Chen, Tin Aung Than, Susan F. Murray, Mariam Aghajan, Jun Zhang
Publikováno v:
Hepatology
BACKGROUND AND AIMS The hepatic mitogen-activated protein kinase (MAPK) cascade leading to c-Jun N-terminal kinase (JNK) activation has been implicated in the pathogenesis of nonalcoholic fatty liver (NAFL)/NASH. In acute hepatotoxicity, we previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83508583500ef97455ec6feb4fe5aab6
https://europepmc.org/articles/PMC8639630/
https://europepmc.org/articles/PMC8639630/
Autor:
Elana B Mitchel, Cynthia Behling, Ayako Suzuki, Katherine P. Yates, Tiange Liu, Noel T. Mueller, Joel E. Lavine
Publikováno v:
J Clin Endocrinol Metab
Context Sex hormones have been linked with presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults, but it is unknown if they affect severity of pediatric NAFLD. Objective To examine associations of circulating SHBG, estrogens, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14cfa3fddea199bf5073923dfcc6cfc
https://europepmc.org/articles/PMC7494240/
https://europepmc.org/articles/PMC7494240/
Autor:
Ayako Suzuki, Kenji Izumi, Tomohito Sato, Reimu Fukui, Osamu Sakata, Tomoaki Kahyo, Shumpei Sato, Eiji Naru, Takashi K. Ito, Ariful Islam, Makoto Horikawa, Mitsutoshi Setou, Emi Hoshikawa, Md. Al Mamun
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2807, p 2807 (2020)
Volume 21
Issue 8
International Journal of Molecular Sciences, Vol 21, Iss 2807, p 2807 (2020)
The vermilion of the human lip is a unique facial area because of certain distinguishing features from the adjacent tissues such as the white lip (skin) and oral mucosa. However, the distinction in terms of molecular distribution between the vermilio
Autor:
Ayako Suzuki, Cynthia D. Guy, Jagpal Singh Klair, Ju Dong Yang, Jeanne M. Clark, Katherine P. Yates, Anna Mae Diehl, Ryan M. Gill, Aynur Unalp-Arida, Manal F. Abdelmalek, Joel E. Lavine
Publikováno v:
Hepatology. 64:85-91
UNLABELLED Postmenopausal women with nonalcoholic steatohepatitis are at an increased risk of hepatic fibrosis compared with premenopausal women. Whether duration of estrogen deficiency in postmenopausal state dictates an individual's fibrosis risk r
Autor:
Anna Mae Diehl, Gregory A. Michelotti, Cynthia D. Guy, Thiago A. Pereira, Mariana Verdelho Machado, Ann Marie Zavacki, Dawn Piercy, Leandi Krüger, Manal F. Abdelmalek, Brittany N. Bohinc, Herbert Pang, Guanhua Xie, Marzena Swiderska-Syn, Ayako Suzuki
Publikováno v:
Endocrinology
Thyroid hormone (TH) is important for tissue repair because it regulates cellular differentiation. Intrahepatic TH activity is controlled by both serum TH levels and hepatic deiodinases. TH substrate (T4) is converted into active hormone (T3) by deio
Autor:
Yamato Mashimo, Toshio Ishikawa, Shin Fujimori, Tomomi Maeda, Maiko Numakura, Yuko Fujimaki, Kazuhiro Eto, Ayako Suzuki, Nakayuki Yoshimura
Publikováno v:
Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 7:143-147
Summary Aims Dipeptidyl-peptidase 4 inhibitors have become one of the most popular antidiabetic drugs. However, what kind of combinations with other drugs were advantageous was not known. Here, we tried to elucidate it in a real-life clinical setting
Autor:
Joseph A. Galanko, Karen D. Corbin, Manal F. Abdelmalek, Kerry Ann Da Costa, Melanie D. Spencer, Cynthia D. Guy, Wei Sha, Ayako Suzuki, Anna Mae Diehl, Steven H. Zeisel, Alfonso Torquati, Diana M. Cardona
Publikováno v:
The FASEB Journal. 27:1674-1689
Choline metabolism is important for very low-density lipoprotein secretion, making this nutritional pathway an important contributor to hepatic lipid balance. The purpose of this study was to assess whether the cumulative effects of multiple single n
Autor:
Cynthia D. Guy, Manal F. Abdelmalek, Arun J. Sanyal, Jeffrey B. Schwimmer, Aynur Unalp–Arida, Anna Mae Diehl, Joel E. Lavine, Katherine P. Yates, Ann O. Scheimann, Ayako Suzuki
Publikováno v:
Clinical Gastroenterology and Hepatology. 10:786-794
Physiological changes that occur during puberty might affect pathologic features of nonalcoholic fatty liver disease (NAFLD). We investigated associations between pubertal development and clinical and histopathologic features of NAFLD.We studied 186
Autor:
Cynthia D, Guy, Ayako, Suzuki, Marzena, Zdanowicz, Manal F, Abdelmalek, James, Burchette, Aynur, Unalp, Anna Mae, Diehl, Katherine, Yates
Publikováno v:
Hepatology. 55:1711-1721
The Hedgehog (Hh) signaling pathway mediates several processes that are deregulated in patients with the metabolic syndrome (e.g., fat mass regulation, vascular/endothelial remodeling, liver injury and repair, and carcinogenesis). The severity of non