Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Akiko Okada"'
Autor:
Yoshiki Imamura, Asako Kubo, Masamichi Shinoda, Jui Yen Chen, Akiko Okada-Ogawa, Koichi Iwata
Publikováno v:
Journal of Oral Science. 62:13-17
Although xerostomia can cause persistent oral pain, the mechanisms underlying such pain are not well understood. To evaluate whether a phosphorylated p38 (pp38)-TRPV4 mechanism in trigeminal ganglion (TG) neurons has a role in mechanical hyperalgesia
Autor:
Hiroki Hamano, Chie Fukuda, Masahiko Takahata, Dai Sato, Yoshiharu Hiruma, Tomohiro Shimizu, Norimasa Iwasaki, Tomoka Hasegawa, Masahiro Ota, Shigeto Hiratsuka, Eisuke Tsuda, Akiko Okada, Ryo Fujita, Norio Amizuka
Publikováno v:
Bone. 116:172-180
The treatment of juvenile osteoporosis has not been established due to a lack of data regarding the efficacy and adverse effects of therapeutic agents. The possible adverse effects of the long-term use of antiresorptive therapies on skeletal growth i
Autor:
Chie Fukuda, Tsuyoshi Karibe, Yoshitaka Isumi, Tomomaya Yamamoto, Tomoka Hasegawa, Seiichiro Kumakura, Nana Takagi, Norio Amizuka, Eisuke Tsuda, Yoshiharu Hiruma, Masanori Koide, Akiko Okada, Shunsuke Uehara, Nobuyuki Udagawa
Publikováno v:
Bone. 155
Recent studies have established the idea that Siglec-15 is involved in osteoclast differentiation and/or function, and it is anticipated that therapies suppressing Siglec-15 function can be used to treat bone diseases such as osteoporosis. We have pr
Autor:
Akiko Okada, Dai Sato, Yoshiharu Hiruma, Chie Fukuda, Norio Amizuka, Masahiro Ota, Tomoka Hasegawa, Norimasa Iwasaki, Ryo Fujita, Eisuke Tsuda, Tomomaya Yamamoto, Masahiko Takahata
Publikováno v:
Bone. 135
Effective treatment of juvenile osteoporosis, which is frequently caused by glucocorticoid (GC) therapy, has not been established due to limited data regarding the efficacy and adverse effects of antiresorptive therapies on the growing skeleton. We p
Autor:
Akiko Okada-Ogawa, Yoshiyuki Tsuboi, Koichi Iwata, Barry J. Sessle, Yoshiki Imamura, Masamichi Shinoda, Masaaki Kiyomoto, Noboru Noma, Kazuo Shibuta
Publikováno v:
The Journal of Neuroscience. 33:7667-7680
Fractalkine (FKN) signaling is involved in mechanical allodynia in the facial skin following trapezius muscle inflammation. Complete Freund's adjuvant (CFA) injection into the trapezius muscle produced mechanical allodynia in the ipsilateral facial s
Publikováno v:
Brain Research. 1359:81-89
The kappa-opioid receptor (KOR) antagonist norbinaltorphimine (nor-BNI) attenuates behavioral antinociception produced by spinal administration of the cannabinoid receptor agonist delta-9-tetrahydorcannabinol (THC). The present study examined the abi
Autor:
Ursula Höpner, Thomas Fischer, Akiko Okada, Naotoshi Yamamura, Kazuki Yano, Yasushi Yoshigae, Juergen Mueller, Osamu Okazaki, Motoko Saito-Yabe, Shinichi Mochizuki, Fumihiko Okada, Yuki Nagayama, Junichi Okada, Yukie Suzuki, Atsushi Kurihara, Yuji Kasuya, Masashi Honma, Toshihiko Ikeda, Silvia Zaja, Nao Fukuda, Eisuke Tsuda
Publikováno v:
Journal of Pharmacy and Pharmacology. 62:985-994
Objectives Our aim was to investigate the effect of PEGylation on the uptake of osteoprotegerin/osteoclastogenesis inhibitory factor (OPG/OCIF) into rat liver, kidney and spleen, and human liver. Methods Copolymer of polyethyleneglycol allylmethyleth
Publikováno v:
Pharmacology. 84:340-345
We studied the effect of scopolamine on radial maze performance during both light and dark periods in sham and suprachiasmatic nucleus (SCN)-lesioned rats. Scopolamine dose-dependently caused a significant increase in the number of total, reference m
Autor:
Akiko Okada-Ogawa, Yoshiki Imamura, Koichi Iwata, Masayuki Kobayashi, Barry J. Sessle, Masamichi Shinoda, Yuka Nakaya, Kozue Kita
Publikováno v:
Experimental neurology. 267
In order to determine if the functional changes in the GABAergic system in the trigeminal spinal subnucleus caudalis (Vc) are involved in the mechanisms underlying extraterritorial neuropathic pain in the orofacial region following inferior alveolar
Autor:
Eli Eliav, Yoshiki Imamura, Takahiro Shinozaki, Kazuhiko Hara, Akiko Okada-Ogawa, Koichi Iwata, Masamichi Shinoda, Kazuyoshi Koike, Noboru Noma, Masatake Asano, Richard H. Gracely
Publikováno v:
The Clinical journal of pain. 30(2)
Objectives: Research suggests that varied etiologic factors areresponsible for burning mouth syndrome (BMS). We examined therole of immune and endocrine function in the pathology of BMS.Methods: We conducted a case-control study to evaluate immune(ly