Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hansell A"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 312:F278-F283
Diabetes mellitus is associated with decreased nitric oxide bioavailability thereby affecting renal blood flow regulation. Previous reports have demonstrated that cellular uptake of l-arginine is rate limiting for nitric oxide production and that pla
Autor:
Malou Friederich-Persson, Fredrik Palm, Masaomi Nangaku, Erik Thörn, Max Levin, Peter Hansell
Publikováno v:
Hypertension. 62:914-919
Diabetic nephropathy is strongly associated with both increased oxidative stress and kidney tissue hypoxia. The increased oxidative stress causes increased kidney oxygen consumption resulting in kidney tissue hypoxia. To date, it has been difficult t
Autor:
Peter Hansell, Angelica Fasching, Liselotte Pihl, Patrik Persson, Gerald F. DiBona, Fredrik Palm
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 303:R39-R47
Glomerular filtration rate (GFR) and renal blood flow (RBF) are normally kept constant via renal autoregulation. However, early diabetes results in increased GFR and the potential mechanisms are debated. Tubuloglomerular feedback (TGF) inactivation,
Autor:
David Bergqvist, Rickard Nyman, Per Liss, Olof Hellberg, Peter Hansell, Per-Ola Carlsson, Fredrik Palm
Publikováno v:
Journal of Vascular and Interventional Radiology. 16:269-274
PURPOSE The renal medulla seems to be particularly vulnerable to vascular injection of iodinated contrast media, particularly in patients with preexisting renal dysfunction. The gas carbon dioxide is frequently used as an alternative to iodinated con
Publikováno v:
Diabetes/Metabolism Research and Reviews. 20:452-459
Diabetes-induced renal complications, i.e. diabetes nephropathy, are a major cause of morbidity and mortality. The exact mechanism mediating the negative influence of hyperglycaemia on renal function is unclear, although several hypotheses have been
Publikováno v:
Hypertension, 64(2), 323-329. Lippincott Williams and Wilkins
Persson, P, Fasching, A, Teerlink, T, Hansell, P & Palm, F 2014, ' L-Citrulline, But Not L-Arginine, Prevents Diabetes Mellitus-Induced Glomerular Hyperfiltration and Proteinuria in Rat ', Hypertension, vol. 64, no. 2, pp. 323-329 . https://doi.org/10.1161/HYPERTENSIONAHA.114.03519
Persson, P, Fasching, A, Teerlink, T, Hansell, P & Palm, F 2014, ' L-Citrulline, But Not L-Arginine, Prevents Diabetes Mellitus-Induced Glomerular Hyperfiltration and Proteinuria in Rat ', Hypertension, vol. 64, no. 2, pp. 323-329 . https://doi.org/10.1161/HYPERTENSIONAHA.114.03519
Diabetes mellitus–induced oxidative stress causes increased renal oxygen consumption and intrarenal tissue hypoxia. Nitric oxide is an important determinant of renal oxygen consumption and electrolyte transport efficiency. The present study investi
Autor:
Malou Friederich-Persson, Peter Hansell, Angelica Fasching, Fredrik Palm, Masaomi Nangaku, Patrik Persson
Publikováno v:
The FASEB Journal. 28
The proposed pathways for the development of nephropathy are many and likely to be complex and overlapping. Recent literature strongly supports a role of renal tissue hypoxia as a pathway to nephropathy but the evidence remains inconclusive as the ro
Publikováno v:
Acta Physiologica Scandinavica. 172:219-226
Dopamine (DA) is an intrarenal natriuretic hormone involved in sodium homeostasis, but the regulation of renal dopaminergic tonus is unclear. We evaluated different pathways for elevating DA tonus to determine which are important for the ability of t
Autor:
Malou Friederich-Persson, Peter Hansell, Patrik Persson, Lina Nordquist, Angelica Fasching, Fredrik Palm
Publikováno v:
Oxygen Transport to Tissue XXXV ISBN: 9781461472568
Intrarenal tissue hypoxia is an acknowledged common pathway to end-stage renal disease in clinically common conditions associated with development of chronic kidney disease, such as diabetes and hypertension. In diabetic kidneys, increased oxygen met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0e1cc9e569cc445a463c43d359970ea
https://doi.org/10.1007/978-1-4614-7411-1_2
https://doi.org/10.1007/978-1-4614-7411-1_2
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461447719
Alterations in glomerular filtration rate (GFR) are one of the earliest indications of altered kidney function in diabetes. Adenosine regulates GFR through tubuloglomerular feedback mechanism acting on adenosine A1 receptor. In addition, adenosine ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df36d55d4159903613d19f5121a69f69
https://doi.org/10.1007/978-1-4614-4989-8_31
https://doi.org/10.1007/978-1-4614-4989-8_31