Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ochi A"'
Autor:
Tsunehiro Ochi, Narufumi Suganuma, Nobuto Okamoto, Masafumi Ono, Toshiji Saibara, Shuhei Noguchi, Kosei Masuda, Kensuke Munekage
Publikováno v:
Hepatology Research. 47:983-990
Background Insulin resistance and type 2 diabetes mellitus (T2DM) contribute to the progression of nonalcoholic fatty liver disease (NAFLD). However, the relationship between glucose metabolic factors and the histological severity in NAFLD patients b
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 310:G273-G284
Feeding strategies to care for patients who transition from enteral nutrient deprivation while on total parenteral nutrition (TPN) to enteral feedings generally proceed to full enteral nutrition once the gastrointestinal tract recovers; however, an i
Autor:
Tsunehiro Ochi, Shuji Sakamoto, Nobuto Okamoto, Masafumi Ono, Masayuki Tsuda, Yoshihiro Hayashi, Kensuke Munekage, Takuma Higuchi, Katsumi Toda, Jude A. Oben, Toshiji Saibara
Publikováno v:
Hepatology Research. 46:584-592
AIM: Nonalcoholic steatohepatitis (NASH) is the major cause of chronic liver disease worldwide. Endoplasmic reticulum (ER) stress is considered to be an important pathological characteristic in NASH. A sequence variation (I148M) in the patatin-like p
Autor:
Hiroshi Aikata, Michio Imamura, Takayuki Fukuhara, Hideyuki Hyogo, Kazuaki Chayama, Hidenori Ochi, Tomokazu Kawaoka, Hiromi Kan, Yohji Honda, Yoshiiku Kawakami, Kikuko Hotta, Tomoki Kobayashi, Akira Hiramatsu, Masataka Tsuge, Noriaki Naeshiro
Publikováno v:
Hepatology Research. 46:E146-E153
Aim A genome-wide association study revealed that the single nucleotide polymorphism (SNP) rs738409 in the patatin-like phospholipase 3 gene (PNPLA3) was strongly associated with non-alcoholic fatty liver disease (NAFLD). Recent pilot studies investi
Autor:
Mark A. Moffat, Kazuyuki Inagaki, Hideaki Shimada, Bernard N. Violand, Shinji Ogawa, Robert H. Arch, Jaime L. Masferrer, Aisuke Nii, Isami Fujita, Madan Katragadda, Takashi Ochi
Publikováno v:
Hepatology Research. 40:1128-1141
Aim: To evaluate the usefulness of a platelet-derived growth factor (PDGF)-B specific monoclonal antibody (mAb) as a therapeutic agent to treat chronic liver fibrosis. Methods: Liver fibrosis was induced in ICR mice by bile duct ligation (BDL) or BAL
Publikováno v:
Journal of Gastroenterology and Hepatology. 25:S67-S74
Background and Aims: The effects of an EP4 agonist/antagonist on the healing of lesions produced by indomethacin in the small intestine were examined in rats, especially in relation to the expression of vascular endothelial growth factor (VEGF) and a
Autor:
Susumu Tazuma, Koji Arihiro, Masayoshi Takeuchi, Sho-ichi Yamagishi, Hideyuki Hyogo, Yoshitaka Nabeshima, Takashi Sato, Hidenori Ochi, Motoki Inoue, Kazuaki Chayama, Tomokazu Ishitobi, Michihiro Nonaka, Keiko Iwamoto
Publikováno v:
Journal of Gastroenterology and Hepatology. 22:1112-1119
Background and Aim: Advanced glycation end products (AGE), senescent macroprotein derivatives formed at an accelerated rate in diabetes, play important roles in the pathogenesis of diabetic vascular complications. Recently, AGE have also been found t
Publikováno v:
Hepatology Research. 25:287-295
It is known that diosgenin alters the lipid composition of hepatic plasma membranes as well as bile lipids. We recently reported that changes in the lipid composition of the canalicular membrane bilayer were associated with alterations of membrane fl
Publikováno v:
Hepatology Research. 25:38-47
Cyclosporine A (CsA) reduces liver canalicular membrane (CM) fluidity to cause a disproportionate reduction of biliary lipid secretion (the uncoupling phenomenon) without affecting adenosine triphosphate-dependent (ABC) transporters except for Mdr1.
Autor:
Motohiro Yokoyama, Norio Koide, Toshiyuki Shinji, Takaaki Mizushima, Mine Harada, Mitsuko Ichimura, Hideaki Hasuoka, Koji Ochi, Tetsuya Tsurumi
Publikováno v:
Pancreas. 24:344-347
INTRODUCTION Matrix metalloproteinase-2 (MMP-2) has an activity to degrade type IV collagen and is associated with invasion angiogenesis of malignant tumor. AIM A diagnostic value of MMP-2 in pancreatic juice was studied in the diagnosis of pancreati