Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Trant, A. (A.)"'
Autor:
Takeshi Miura, Sonoko Yamaguchi, Shinji Adachi, Kohei Yamauchi, Chiemi Miura, Yukinori Kazeto, John M. Trant, Mayuko Kohara
Publikováno v:
Biology of Reproduction. 79:938-946
Two gonadotropins (Gths), follicle-stimulating hormone (Fsh) and luteinizing hormone (Lh), control gonadal steroidogenesis and gametogenesis in vertebrates, including teleost fish. Here, we report on the production of biologically active recombinant
Autor:
J M Trant, Yukinori Kazeto
Publikováno v:
Journal of Molecular Endocrinology. 35:571-583
Cytochrome P450 aromatase (CYP19) converts androgens to estrogens. Unlike mammals, teleosts have two CYP19 genes, expressed differentially in ovary (CYP19A1) and neuronal tissues (CYP19A2). The primary purpose of this study was to demonstrate the pot
Autor:
R. Sampath Kumar, John M. Trant
Publikováno v:
General and Comparative Endocrinology. 136:82-89
A determination of the seasonal changes in the expression of the genes encoding the subunits of gonadotropic hormones is an important first step in the understanding of the molecular control of the onset of puberty and the reproductive cycle in fish.
Publikováno v:
Fish Physiology and Biochemistry. 28:29-32
Cytochrome P450-aromatase (CYP19) is the critical steroidogenic enzyme controlling estrogen biosynthesis. In teleosts, two genes for CYP19 are found with CYP19A1 expressed mainly in the ovary and CYP19A2 expressed in both brain and pituitary. The pro
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 129:375-380
Perciforms have three forms of gonadotropin-releasing hormone (GnRH) in their brain. All three GnRHs are potent secretogogues for luteinizing hormone (LH) from the pituitary. The pivotal role of GnRH-R-GnRH interactions in reproductive homeostasis is
Publikováno v:
Biology of Reproduction. 63:1676-1682
In vertebrates, the growth and maturation of the ovarian follicle is dependent on the appropriate dynamics of sex steroid secretion, which is dictated by gene expression of the steroidogenic enzymes. The molecular aspects of steroid regulation are po
Publikováno v:
Molecular and Cellular Endocrinology. 168:65-75
Gonadotropin-releasing hormones (GnRHs) bind to the specific receptor present on the gonadotrophs to activate the synthesis and release of gonadotropins (follicle stimulating hormone or FSH and luteinizing hormone or LH), which in turn control gonada
Autor:
Deoraj Alok, Andrew H. Dittman, John M. Trant, Yonathan Zohar, R. Sampath Kumar, Katherine E. Kight, Shigeho Ijiri, Penny Swanson
Publikováno v:
Molecular and Cellular Endocrinology. 167:1-9
The thyroid stimulating hormone receptor (TSHR) mediates the pituitary control of the development, growth and function of the thyroid. The expression of the gene encoding this receptor is known only in the thyroid, lymphocytes, fibroblasts, retro-orb
Autor:
John M. Trant, S. Nunez
Publikováno v:
Fish Physiology and Biochemistry. 19:293-304
The conversion of 3b-hydroxy-δ5 steroids into their respective biologically active 3-keto-δ4 steroid counterparts is catalyzed by a microsomal enzyme, 3β-hydroxysteroid dehydrogenase /5-ene-4-ene isomerase (3β-HSD). In order to study this enzyme
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 61:393-397
The cDNA encoding the catfish ovarian aromatase has previously been isolated and described (accession number S75715). As demonstrated previously, the predicted amino acid sequence and enzymatic activity of the encoded protein share a significant degr