Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kurt W. Evans"'
Autor:
Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W. Evans, Erkan Yuca, Stephen Scott, Bryce P. Kirby, Xiaofeng Zheng, Senthil Damodaran, Funda Meric-Bernstam
Publikováno v:
Cancer Research. 82:P5-08
Purpose: Several FGFR alterations have been found in breast cancer, however, their role as a therapeutic target in breast has been controversial. Futibatinib (TAS-120; Taiho) is a novel, selective pan-FGFR inhibitor which irreversibly binds to and in
Autor:
Kakajan Komurov, Prahlad T. Ram, Piyush Gupta, Jason I. Herschkowitz, Brett G. Hollier, Alicia Y. Zhou, Robert A. Weinberg, Kurt W. Evans, Tamer T. Onder, Sendurai A. Mani, Supriya Gupta, Joseph H. Taube, Jing Yang, Eric S. Lander, Jeffrey M. Rosen, Kimberly A. Hartwell
Publikováno v:
Proceedings of the National Academy of Sciences. 107:15449-15454
The epithelial-to-mesenchymal transition (EMT) produces cancer cells that are invasive, migratory, and exhibit stem cell characteristics, hallmarks of cells that have the potential to generate metastases. Inducers of the EMT include several transcrip
Autor:
Rui Yu Wang, Cathrin Brisken, Venkata Lokesh Battula, Brett G. Hollier, Rudy Guerra, Yuexi Shi, Ayyakkannu Ayyanan, Sendurai A. Mani, Kurt W. Evans, Michael Andreeff, Frank C. Marini
Publikováno v:
Stem Cells. 28:1435-1445
The epithelial-to-mesenchymal transition (EMT) is an embryonic process that becomes latent in most normal adult tissues. Recently, we have shown that induction of EMT endows breast epithelial cells with stem cell traits. In this report, we have furth
Autor:
Argun Akcakanat, Kurt W. Evans, Farrell Adkins, Filip Janku, Denái R. Milton, Kim Anh Do, Yisheng Li, Caimiao Wei, Funda Meric-Bernstam, Huiqin Chen, Ashley M. Holder
Publikováno v:
Oncotarget
Scopus-Elsevier
Scopus-Elsevier
// Ashley M. Holder 1, 2 , Argun Akcakanat 3 , Farrell Adkins 4 , Kurt Evans 3 , Huiqin Chen 5 , Caimiao Wei 5 , Denai R. Milton 5 , Yisheng Li 5 , Kim-Anh Do 5 , Filip Janku 3 , Funda Meric-Bernstam 1, 3 1 Department of Surgical Oncology, The Univer
Autor:
Kurt W. Evans, Changping Li, S. Jackson, Hui Gao, Massimo Cristofanilli, Gabriel N. Hortobagyi, Michal Mego, Antonio Giordano, Bang Ning Lee, James M. Reuben, Anthony Lucci, Sendurai A. Mani, Evan N. Cohen
Epithelial cancer cells are likely to undergo epithelial-mesenchymal transition (EMT) prior to entering the peripheral circulation. By undergoing EMT, circulating tumor cells (CTCs) lose epithelial markers and may escape detection by conventional met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a0154698eb05bba2ce83b677a113d2
https://europepmc.org/articles/PMC3169728/
https://europepmc.org/articles/PMC3169728/
The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies
Publikováno v:
Journal of mammary gland biology and neoplasia. 14(1)
During cancer progression, some cells within the primary tumor may reactivate a latent embryonic program known as epithelial-to-mesenchymal transition (EMT). Through EMT, transformed epithelial cells can acquire the mesenchymal traits that seem to fa