Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Lester Packer"'
Publikováno v:
Toxicology. 179:171-180
Isoflavonoids are thought to be the biologically active components in soy that play a role in the prevention of coronary heart disease and breast and prostate cancer. Mechanisms to explain how isoflavonoids mediate beneficial effects have not yet bee
Publikováno v:
Journal of Agricultural and Food Chemistry. 50:166-171
Antioxidant activities of freeze-dried preparations of a 70% acetone extract of pomegranate (Punica granatum L.) and its three major anthocyanidins (delphinidin, cyanidin, and pelargonidin) were evaluated. Free radical scavenging activities were exam
Publikováno v:
Antioxidants & Redox Signaling. 3:711-719
Addition of glucose to activated RAW 264.7 macrophages or addition of mitochondrial electron-transfer chain inhibitors enhanced the cellular nitric oxide production. An additive effect of rotenone or antimycin A and glucose on enhancing nitric oxide
Publikováno v:
Biochemical Pharmacology. 61:547-554
The aim of this study was to investigate the effect of the mitochondrial cofactor alpha-lipoic acid [R (+) LA] or its lipoamide analogue, 2-(N,N-dimethylamine) ethylamido lipoate [R (+) LA-plus], on nitric oxide (NO) production in RAW 264.7 macrophag
Publikováno v:
Toxicology. 148:119-123
The free radical scavenging activities and inhibitory effect of lipid peroxidation of a delphinidin derivative in eggplant were investigated. Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside (nasunin), an anthocyanin, was isolated as purple colored
Autor:
Lester Packer, Qiong Guo
Publikováno v:
Redox Report. 4:105-111
The recycling of Trolox, a water-soluble vitamin E homologue, by coenzyme Q0 (CoQ0) during Cu2+-initiated oxidation of ascorbate in mouse skin homogenates was investigated using electron spin resonance (ESR) spectroscopy. In a mixture containing CoQ0
Autor:
Huibi Xu, Jingwu Hou, Lester Packer, Baolu Zhao, Taotao Wei, Wenjuan Xin, Chang Chen, Zhonghong Gao
Publikováno v:
IUBMB Life. 47:397-405
The present study was conducted to evaluate the different effects of the constituents of EGb761 (Ginkgo biloba Extract) on apoptosis in cerebellar granule cells induced by hydroxyl radicals. The total flavonoid component of EGb761, two pure EGb761 co
Autor:
Lester Packer, Sashwati Roy, Josef Pallauf, Fabio Virgili, Alexandra Fischer, D. Höhler, Gerald Rimbach
Publikováno v:
Archiv für Tierernaehrung. 52:203-222
Oxidative stress results from a disruption of the prooxidant/antioxidant cellular balance and monitoring free radical status becomes an interesting challenge in animal and human nutrition. In the present work, merits and limitations of different anal
Autor:
Masahiro Kohno, Kanae Fujii, Yuji Odagaki, Toshiki Masumizu, Lester Packer, Mamoru Imanari, Akitane Mori, Soichi Nagai
Publikováno v:
IUBMB Life. 46:707-717
In vivo electron spin resonance imaging (ESR imaging) was applied to living mice after peroral administration of a nitroxide radical spin probe. A 3D ESR imaging procedure was applied in vivo in order to obtain the exact distribution of the spin prob
Publikováno v:
Free Radical Biology and Medicine. 25:287-297
Mono-thiols can act either as pro- or anti-oxidants during metal-catalyzed low density lipoprotein (LDL) peroxidation, however investigation of the role of vicinal thiols has been neglected. Therefore dihydrolipoic acid (DHLA), a vicinal dithiol, and