Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Chenxin Cai"'
Publikováno v:
Analytical Chemistry. 92:5302-5310
MicroRNAs (miRNAs) in cancer cell-derived exosomes are important cancer biomarkers. Herein, a sensitive hybridization chain reaction (HCR) electrochemical assay was fabricated for the detection of exosomal microRNA-122 (miR-122). The hairpin DNA (hpD
Publikováno v:
Analytica Chimica Acta. 1064:33-39
The detection of sequence-specific microRNAs (miRNAs) is an important factor to the diseases diagnosis. Herein, a triple signal amplification electrochemical biosensor for highly sensitive detection of miRNA-21 was developed based on a duplex-specifi
Autor:
Bin Qiao, Juqian Jiang, Bangshun He, Qunqun Guo, Jian Shen, Chenxin Cai, Hui Zhang, Yunlong Qi
Publikováno v:
The Analyst. 144:3668-3675
Exosomes are non-invasive biomarkers for cancer diagnosis. Herein, we describe an electrochemiluminescent (ECL) aptasensor for the detection of exosomes from breast tumor cells. Mercaptopropionic acid (MPA)-modified Eu3+-doped CdS nanocrystals (MPA-C
Publikováno v:
Analytica chimica acta. 1130
Exosomes are extracellular nanovesicles for transferring and delivering membrane and cytosolic molecules between cells. Detection and profiling of exosomal proteins can provide direct information on disease progression, which is important to the earl
Publikováno v:
The Analyst. 143:3353-3359
In this paper, a dual-signal ratiometric electrochemiluminescence (ECL) assay was developed to detect human DNA (cytosine-5)-methyltransferase1 (DNMT1) activity. Mercaptopropionic acid (MPA)-modified Eu3+-doped CdS nanocrystals (MPA-CdS:Eu NCs) and l
Publikováno v:
The Analyst. 143:2051-2056
The levels of 5-methylcytosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) in DNA (5-mC-DNA and 5-hmC-DNA) are strongly correlated with cancer occurrence and development. The ability to distinguish and quantitatively detect them is important for cance
Publikováno v:
Analytical Chemistry. 88:3935-3944
Hematin-induced fluorescence quenching of boron-doped graphene quantum dots (BGQDs) allows for determination of hematin concentration in human erythrocytes with no need for separating hematin from hemoglobin before performing the assay. The BGQDs are
Publikováno v:
Biosensors and Bioelectronics. 74:98-103
The expression profile of vascular endothelial growth factor (VEGF) is highly correlated with the occurrence and development of cancer. This work reports an electrochemiluminescence (ECL) approach for highly sensitive detection of VEGF165. This appro
Publikováno v:
Analytical chemistry. 90(7)
Sensitive and specific detection of tumor exosomes is of great significance for early cancer diagnosis. In this paper, we report an aptamer strategy for exosome detection based on aptamer recognition-induced multi-DNA release and cyclic enzymatic amp
Publikováno v:
Analytical chemistry. 88(22)
Effective detection of DNA methyltransferase (DNMT) activity is significant for cancer research. Herein, we developed a sensitive electroanalytical method to detect human DNA (cytosine-5)–methyltransferase 1 (DNMT1) from crude lysates of cancer cel