Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mong Heng Wang"'
Publikováno v:
Prostaglandins & Other Lipid Mediators. 122:45-53
Arachidonic acid (AA) is metabolized by cyclooxygenase (COX) and cytochrome P450 (CYP) enzymes into eicosanoids, which are involved in cardiovascular diseases and stroke. Evidence has demonstrated the important functions of these eicosanoids in regul
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H2187-H2195
Previous studies have shown that the synthesis of renal cytochrome P-450 (CYP)-derived eicosanoids is downregulated in genetic or high-fat diet-induced obese rats. Experiments were designed to determine whether fenofibrate, a peroxisome proliferator-
Autor:
Yiqiang Zhou, Michael W. Brands, Cong-Yi Wang, John R. Falck, Juan Du, Venugopal T. Raju, Mong Heng Wang, Hui Huang, Hsin Hsin Chang
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F1116-F1122
We previously reported that inhibition of nitric oxide (NO) synthesis by N-nitro-l-arginine methyl ester (l-NAME) during late pregnancy leads to increased production of renal vascular 20-hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P-450 (CYP
Autor:
Anne M. Dorrance, Yiqiang Zhou, Songbai Lin, Zheng Dong, Michael W. Brands, Hsin Hsin Chang, Mong Heng Wang, Juan Du
Publikováno v:
American Journal of Hypertension. 18:530-537
Background Renal cytochrome P450 (CYP)-derived eicosanoids, hydroxyeicosatetraenoic acids (HETEs), epoxyeicosatrienoic acids (EETs), and dihydroxyeicosatrienoic acids (DHETs), have been shown to affect renal function and blood pressure (BP). We recen
Autor:
Songbai Lin, Anita Smith, Yiqiang Zhou, John D. Imig, Hsin Hsin Chang, Anne M. Dorrance, Mong Heng Wang, Xueying Zhao
Publikováno v:
Hypertension. 42:594-599
The incidence of essential hypertension increases with obesity; however, the mechanisms that link obesity with hypertension are unclear. Renal cytochrome P450 (CYP)-derived eicosanoids—hydroxyeicosatetraenoic acids (HETEs), epoxyeicosatrienoic acid
Autor:
Mong Heng Wang, V. Raj Gopal, Ji Shi Wang, Alberto Nasjletti, Michal Laniado-Schwartzman, John R. Falck, Fan Zhang, Jun Ichi Kaide
Publikováno v:
American Journal of Physiology-Renal Physiology. 284:F51-F56
20-HETE, a cytochrome P-450 4A (CYP4A1)-derived arachidonic acid metabolite, is a major eicosanoid formed in renal and extrarenal microcirculation. 20-HETE inhibits Ca2+-activated K+ channels in vascular smooth muscle cells and thereby may modulate v
Autor:
Krishna Rao Maddipati, Pengcheng Luo, Xuan Zheng, Weiguo Li, Mong Heng Wang, Yi Zhang, Nasrul Hoda, Tsugio Seki, Adviye Ergul
20-Hydroxyeicosatetraenoic acid (20-HETE), Cyp4a-derived eicosanoid, is a lipid mediator that promotes tumor growth, as well as causing detrimental effects in cerebral circulation. We determined whether concurrent inhibition of cyclooxygenase-2 (COX-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7324a046815e4dc74f61bcd0aebee19
https://europepmc.org/articles/PMC4214836/
https://europepmc.org/articles/PMC4214836/
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 276:R1691-R1700
20-Hydroxyeicosatetraenoic acid (HETE), the cytochrome P-450 (CYP) 4A ω-hydroxylation product of arachidonic acid, has potent biological effects on renal tubular and vascular functions and on the control of arterial pressure. We have expressed high
Autor:
Pengcheng Luo, Mong Heng Wang
Publikováno v:
Prostaglandinsother lipid mediators. 95(1-4)
Arachidonic acid (AA) is metabolized by cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes into eicosanoids, which are involved in diverse diseases, including type 1 and type 2 diabetes. During the last thirty years, evidence
Autor:
Fan Zhang, Mong Heng Wang, John R. Falck, U. Murali Krishna, Michal Laniado-Schwartzman, Alberto Nasjletti
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 38(6)
Small mesenteric arteries of spontaneously hypertensive (SHR) and Wistar-Kyoto rats (WKY) were compared for the production of 20-HETE and the effects of 20-HETE and N -methylsulfonyl-12,12-dibromododec-11-enamide (DDMS, 30 μmol/L), a 20-HETE synthes