Zobrazeno 1 - 10
of 40
pro vyhledávání: '"G. Caleb Alexander"'
Autor:
Jiajia Zhang, Jessica Y Islam, Jing Sun, Xueying Yang, Sharon Weissman, Qulu Zheng, Keith A. Crandall, Siyuan Guo, Todd T. Brown, Xiaoming Li, Kathleen M Andersen, Hana Akelsrod, Gregory D. Kirk, Bankole Olatosi, Roslyn B. Mannon, Evan French, Rena C Patel, Teresa Po-Yu Chiang, Richard A. Moffitt, Melissa Haendel, Nora Francheschini, Amy L. Olex, G Caleb-Alexander, Amanda J. Vinson, Christopher G. Chute
Publikováno v:
The Lancet. HIV
Background Evidence of whether people living with HIV are at elevated risk of adverse COVID-19 outcomes is inconclusive. We aimed to investigate this association using the population-based National COVID Cohort Collaborative (N3C) data in the USA. Me
Publikováno v:
Addiction. 117:969-976
BACKGROUND AND AIMS Despite prescribing declines between 2011 and 2019, opioid morbidity and mortality in the United States continued to rise during this period. We estimated the relationship between opioid prescribing, opioid use disorder (OUD) and
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 1, Pp 153-162 (2021)
Clinical and Translational Science, Vol 14, Iss 1, Pp 153-162 (2021)
Many academic institutions are collecting blood samples from patients seeking treatment for coronavirus disease 2019 (COVID‐19) to build research biorepositories. It may be feasible to extract pharmacogenomic (PGx) information from biorepositories
Autor:
Ken Ogasawara, G. Caleb Alexander
Publikováno v:
Clinical Pharmacology in Drug Development. 8:914-921
Biologics, especially monoclonal antibodies, are increasingly important in the pharmaceutical marketplace. Population pharmacokinetic (PK) analyses could be useful to guide the need for dose adjustments among special populations, yet it is unknown ho
Autor:
Matthew Daubresse, G. Caleb Alexander, Deidra C. Crews, Dorry L. Segev, Mara McAdams-DeMarco, Krista L. Lentine
Publikováno v:
BMC Nephrology
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
BMC Nephrology, Vol 22, Iss 1, Pp 1-10 (2021)
Background Individuals undergoing hemodialysis in the United States frequently report pain and receive three-fold more opioid prescriptions than the general population. While opioid use is appropriate for select patients, high-dose utilization may co
Publikováno v:
American Journal of Nephrology. 49:20-31
Background: Hemodialysis (HD) patients frequently experience pain. Previous studies of HD patients suggest increased opioid prescribing through 2010. It remains unclear if this trend continued after 2010 or declined with national trends. Methods: Lon
Autor:
Omar Mansour, Francine Chingcuanco, G. Caleb Alexander, Ellen Hu, David W. Dowdy, Jeromie Ballreich, Harold A. Pollack
Publikováno v:
JAMA Netw Open
Importance The US opioid epidemic is complex and dynamic, yet relatively little is known regarding its likely future impact and the potential mitigating impact of interventions to address it. Objective To estimate the future burden of the opioid epid
Tobacco control policies and smoking cessation treatment utilization: A moderated mediation analysis
Autor:
Joanna E. Cohen, Jon S. Vernick, Kira E. Riehm, Ramin Mojtabai, Johannes Thrul, G. Caleb Alexander
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0241512 (2021)
PLoS ONE, Vol 16, Iss 8, p e0241512 (2021)
Background Tobacco policies, including clean indoor air laws and cigarette taxes, increase smoking cessation in part by stimulating the use of cessation treatments. We explored whether the associations between tobacco policies and treatment use varie
Publikováno v:
Drug and alcohol dependence. 219
Background Evidence suggests that over 50 % of individuals who used prescription opioids non-medically obtained their prescription from friends or family. Despite its high consequence, reliable opioid diversion prevalence estimates are lacking due to
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
BMC Medicine
BMC Medicine
Background Previous studies on high-risk opioid use have only focused on patients diagnosed with an opioid disorder. This study evaluates the impact of various high-risk prescription opioid use groups on healthcare costs and utilization. Methods This